Sexual Health Topic Homepage

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The Hypogonadism Knowledge Centre is a free resource for healthcare professionals involved in the diagnosis, treatment and monitoring of patients with the condition. Users can expect to find disease awareness sections covering epidemiology, pathophysiology, signs and symptoms and current best practice treatment guidelines. 

The publications digest section of this resource is regularly updated with analysis and commentary on recent scientific articles related to male hypogonadism. There are currently over 50 articles available in the publications digest area, which can be filtered by year or by the following comorbidities:

  • Diabetes
  • Obesity
  • Cardiovascular
  • Mood and behaviour
  • Sexual health

A resources area also contains downloadable materials and links to useful tools, societies and other external websites. 

This resource has been produced in collaboration with Bayer AG, with content provided by Bayer AG.
G.MKT.GM.MH.01.2016.0364

Clinical Case Studies

HIV and Syphilis in Pregnancy

Infection: Genitourinary Infection

Nneka Nwokolo, Consultant in Genitourinary Medicine, Chelsea and Westminster Hospital, Chelsea and Westminster NHS Foundation Trust, London, UK

Case History
A 35-year-old Ethiopian woman was referred from the antenatal clinic with the following results from her booking blood tests: human immunodeficiency virus type 1 (HIV-1) antibody-positive, venereal disease research laboratory (VDRL) test 1:64, syphilis immunoglobulin G/immunoglobulin M positive, Treponema pallidum particle agglutination (TPPA) positive. She was 20 weeks pregnant with her fourth child.

Cryptococcal Disease in HIV

Infection: HIV Infection

Neil D. Ritchie, Clinical Lecturer in Infectious Diseases, Medical Faculty, University of Glasgow, Glasgow, UK

Case History
A 43-year-old Zimbabwean woman presented with headache and meningism of several weeks' duration.

Latest News

Medical Videos

The Risk Factors Associated With Sexually Transmitted Diseases
The Risk Factors Associated With Sexually Transmitted Diseases

Recent Drug Updates

Medical Journal Abstracts on Sexual Health

Comparing blastocyst quality and live birth rates of intravaginal culture using INVOcell™ to traditional in vitro incubation in a randomized open-label prospective controlled trial.

Wed 03 Feb 2016 -  Comparing blastocyst quality and live birth rates of intravaginal culture using INVOcell™ to traditional in vitro incubation in a randomized open-label prospective controlled trial.

Purpose: The purpose of this study is to to compare the efficacy of intravaginal culture (IVC) of embryos in INVOcell™ (INVO Bioscience, MA, USA) to traditional in vitro fertilization (IVF) ...

Sofosbuvir treatment and hepatitis C virus infection.

Thu 28 Jan 2016 -  Sofosbuvir treatment and hepatitis C virus infection.

Hepatitis C virus (HCV) infection is a serious problem worldwide. The use of interferon-based therapy has made HCV eradication challenging. The recent appearance of direct-acting antiviral agents ...

Medical Images

HIV-1 genome
HIV-1 genome
gp120 and the CCR5 co-receptor
 gp120 and the CCR5 co-receptor
HIV envelope glycoprotein
HIV envelope glycoprotein
HIV-1 group M subtypes and CRFs
HIV-1 group M subtypes and CRFs
Pneumocystis jirovecii pneumonia
Pneumocystis jirovecii pneumonia
Key events leading up to the era of HAART
Key events leading up to the era of HAART

Clinical Guidelines

Guidelines on Male Sexual Dysfunction

Mar 2016

These guidelines include 4 sections. The aim of the first two sections is to present the current..

... evidence for the diagnosis and treatment of patients suffering from erectile dysfunction (ED) and premature ejaculation (PE). ED and PE are the two main complaints in male sexual medicine. Pharmacological therapies have completely changed the diagnostic and therapeutic approach to ED.

The aim of the third section is to provide the practicing urologist with the most recent evidence on the diagnosis and management of penile curvature in order to assist in their decision-making. Penile curvature is a common urological disorder which can be congenital or acquired. Congenital curvature is briefly discussed in these guidelines as a distinct pathology in the adult population without any other concomitant abnormality present (such as urethral abnormalities). For paediatric congenital penile curvature, please refer to the EAU Guidelines on Paediatric Urology, Chapter on Congenital Penile Curvature. Acquired curvature is mainly due to Peyronie’s disease but can also be due to the development of fibrosis following penile fracture.

The aim of the fourth section is to present the current evidence for the diagnosis and treatment of patients suffering from priapism.

2015 UK national guideline for the management of infection with Chlamydia trachomatis

Mar 2016

This guideline offers recommendations on the diagnostic tests, treatment regimens and health..

... promotion principles needed for the effective management of Chlamydia trachomatis genital infection. It covers the management of the initial presentation, as well the prevention of transmission and future infection. The guideline is aimed at individuals aged 16 years and older presenting to healthcare professionals working in departments offering Level 3 care in sexually transmitted infections management within the UK. However, the principles of the recommendations should be adopted across all levels, using local care pathways where appropriate.

Clinical Trials

Miami Membrane for Potency (MMEP) Trial (MMEP)

Fri 01 Apr 2016

The use of dehydrated human amnionic membrane allograft will result in an absolute 20% increase (from 40-60%) in the proportion of men considered potent (Sexual History Inventory for Men (SHIM) ...

True NTH Sexual Recovery Intervention for Prostate Cancer Survivors and Their Partners

Tue 01 Mar 2016

There is increasing evidence that sexual activity is associated with greater resilience and higher well-being in older adults. Even at a time of stress, and even during a late stage of illness, men ...

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