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Podiatry Topic Homepage
Podiatry Overview
Podiatry is the medical science detailing the study, prevention, diagnosis and appropriate management of diseases of the foot and ankle.
The foot plays an essential role in standing and locomotion.1 It supports the body's weight during standing, levers it forward during walking, and absorbs shock during running and jumping.1 The foot is exposed to forces between two and four times a person's bodyweight...
... during running, and jumping.2 This intense and repeated exposure makes the foot the site of many problems.2
The foot can be affected by a variety of congenital, inflammatory, infectious, degenerative, and neoplastic disorders.1 Foot pain is a highly prevalent condition reported by at least one in five people in the general population.3 The prevalence of foot pain increases with age, and is more prevalent in women and the obese.3 It can be quite disabling as it can interfere with the ability to work, perform daily tasks, and participate in recreational activities.2 Many patients with common chronic diseases like osteoporosis, diabetes and obesity, have foot problems that limit their ability to treat their disease with physical exercises.2
Disease of the foot represents a major health problem in patients with diabetes, and is the source of enormous cost to healthcare services.4 Healing is delayed and uncertain, and the incidence of amputation has been reported to be as high as 27%, even in expert centres.4 Since the options for specific therapy are limited, greater emphasis is placed on prevention, and on foot care education in particular.4
1. Bianchi S. et al. Ultrasound of the musculoskeletal system. Medical Radiology. Edition Springer. 2007 ; 2-3 : 835-888
2. Shahady E. Primary care of musculoskeletal problems in the outpatient setting. Edition Springer. 2006 ; 15 : 310
3. Menz H.B. et al. Predictors of podiatry utilisation in Australia: the North West Adelaide Health Study. Journal of Foot and Ankle Research. August 2008 ; 1 : 8
4. Lincoln N.B. et al. Education for secondary prevention of foot ulcers in people with diabetes: a randomised controlled trial. Diabetologia. August 2008 ; 51 : 1954-1961
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Drug News
Phase III trials of DSC 127 (Derma Sciences) start for Diabetic Foot Ulcers
15-02-2013Derma Sciences, Inc. has announced enrollment of patients has commenced in the first of two Phase III clinical trials with the Company’s investigational topical drug candidate DSC 127.
DSC 127 is an analog of a naturally occurring peptide, Angiotensin. It has been shown to increase keratinocyte proliferation, increase extracellular matrix production, and increase vascularization. ...
Tavaborole (Anacor Pharma) success in Phase III for Onychomycosis
02-02-2013
Anacor Pharmaceuticals has announced positive preliminary results from the first of two Phase III trials of tavaborole, its topical anti-fungal for Onychomycosis, a fungal infection of the nail and nail bed that affects approximately 35 million people in the United States. Tavaborole achieved a high degree of statistical significance on all primary and secondary endpoints.
In this...
Two Phase III studies of efinaconazole (Valeant Pharma) show positive results in patients with Onychomycosis
28-11-2012Positive results have been published from two pivotal, Phase III multicenter, randomized, double-blind, vehicle-controlled studies of efinaconazole, from Valeant Pharma, that were conducted in 1,655 subjects with Onychomycosis. The study's primary endpoint was the complete cure rate at Week 52, meaning the target nail showed no clinical involvement and no evidence of fungus present by both KOH...
Podiatry Drug Data - A-Z
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Clinical Trials
Medico-economical Assessment of Telemedicine During Chronic Diabetes-related Foot Wound Management (AIRPEDIA)
15-03-2013The aim of the study is to assess the cost-effectiveness of telemedicine in the care of chronic diabetic foot ulcers.
An Open,Single-centre Pilot Study of Efficacy and Safety of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)
15-03-2013Assess efficacy and safety of topical MOB015B, applied daily during 48 weeks, in adults with fungal nail infection.
Medical Videos
Medical Journal Abstracts
Compressive tibiofemoral force during crouch gait
Gait & Posture
Dec 2011
Crouch gait, a common walking pattern in individuals with cerebral palsy, is characterized by excessive flexion of the hip and knee. Many subjects with crouch gait experience knee pain, perhaps because of elevated muscle forces and joint loading. The goal of this study was to examine how muscle forces and compressive..
Do Weight-bearing Films Affect Decision Making in Hallux Valgus Surgery?
Journal of Foot and Ankle Surgery
Dec 2011
Hallux valgus is a complex deformity of the first ray and forefoot that can be surgically treated using different procedures and osteotomies. Preoperative planning includes anteroposterior and lateral plain films. The effect of weight-bearing on the results of the standardized measurements is still the subject of..
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