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Medical Journal Abstracts on Pain Management

Transcutaneous supraorbital neurostimulation in "de novo" patients with migraine without aura: the first Italian experience.

-94 days ago -  Transcutaneous supraorbital neurostimulation in "de novo" patients with migraine without aura: the first Italian experience.

BACKGROUND: Transcutaneous supraorbital neurostimulation (tSNS) has been recently found superior to sham stimulation for episodic migraine prevention in a randomized trial. We evaluated both the ...

A phase 3, multi-center, randomized, double-blind, placebo-controlled, safety, tolerability, and efficacy study of Xtampza ERTM in patients with moderate-to-severe chronic low back pain.

Thu 06 Aug 2015 -  A phase 3, multi-center, randomized, double-blind, placebo-controlled, safety, tolerability, and efficacy study of Xtampza ERTM in patients with moderate-to-severe chronic low back pain.

Opioid analgesics are commonly used for the treatment of chronic low back pain (CLBP), however abuse potential is a major concern. This study used a randomized, double-blind, placebo-controlled, ...

Clinical Guidelines

Guidelines on Chronic Pelvic Pain

Mar 2015

The European Association of Urology (EAU) Guidelines Working Group for Chronic Pelvic Pain prepared..

... this guidelines document to assist urologists and medical professionals from associated specialties, such as gynaecologists, psychologists, gastroenterologists and sexologists, in assessing the evidence-based management of CPP and to incorporate evidence-based recommendations into their every-day clinical practice.

Management of chronic pain

Dec 2013

This guideline provides recommendations based on current evidence for best practice in the..

... assessment and management of adults with chronic non-malignant pain in non-specialist settings. It does not cover: - interventions which are only delivered in secondary care. - treatment of patients with headache - children. While chronic pain occurs in children, some of their treatment options are different to those of adults, and evidence on the paediatric population has not been included in this remit. - underlying conditions. Chronic pain is caused by many underlying conditions. The treatment of these conditions is not the focus of this guideline so the search strategies were restricted to the treatment of chronic pain, not specific conditions.

Clinical Trials

Impact of Physical Activity and Vitamin D on Osteoarthritic Knee Pain

Thu 13 Nov 2014

Knee Osteoarthritis (KOA) is a major cause of pain and disability, particularly in those of increasing age and body fat. As there are no very effective therapies for KOA, disease often progresses ...

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003

Mon 10 Nov 2014

The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as Monotherapy compared with placebo in participants with signs and symptoms of osteoarthritis of ...

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