Assessment
Spirometry tests
- FEV1 and forced vital capacity (FVC): the recommended method of measuring airflow limitation and reversibility to establish a diagnosis of asthma
- The degree of FEV1 reversibility that indicates a diagnosis of asthma is generally accepted as ≥12% (or ≥200 ml) from the pre-bronchodilator value. However, as most patients do not exhibit reversibility at each assessment, particularly those on treatment, the test lacks sensitivity (repeated testing at different visits is advised)
- Spirometry is reproducible, but effort-dependent. Therefore, proper instructions on how to perform the forced expiratory maneuver must be given to patients, and the highest value of three recordings taken
- Ethnic differences in spirometric values have been demonstrated, and the normal range of values is wider and predicted values are less reliable in subjects <20 years and >70 years of age
- Many lung diseases may result in reduced FEV1. A useful assessment of airflow limitation is the ratio of FEV1 to FVC. This ratio is normally >0.75 to 0.80, and possibly >0.90 in children.
Any values less than these suggest airflow limitation.