Oncology Topic Homepage

Prostate Cancer Learning Hub

,Prostate Cancer Learning Hub

Prostate cancer is the third most frequently diagnosed cancer in Europe and the most common cancer among European men,1 making it a major cause of morbidity. Risk factors for prostate cancer include, increasing age, genetic susceptibility, glucose intolerance and environmental factors.2

The Prostate Cancer Learning Hub has been designed with the busy healthcare professional in mind. The resource conveniently organises a range of up-to-date education content, reference materials and decision support tools, all focussing on prostate cancer.

The disease awareness section provides you with access to a Prostate Cancer Knowledge Centre, which has been developed to provide you with easy to digest best practice guidance for the treatment and management of patients with prostate cancer. In addition access to editorials of key journal publications, an events calendar, video channel, patient materials and interactive healthcare professionals tools are also available.

References

  1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403. EUCAN fact sheet. Estimated incidence, mortality & prevalence, 2012.
  2. Tewari R, Rajender S, Natu SM et al. Diet, obesity, and prostate health: are we missing the link? J Androl 2012;33:763-776.

     

Soft Tissue Sarcoma

Soft Tissue Sarcoma

Soft Tissue Sarcomas (STS) are malignant (cancerous) tumors that develop in tissues which connect, support, or surround other structures and organs of the body. Muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues are types of soft tissue.

Management of soft tissue sarcoma depends on the stage of disease and histological subtype.1 Surgery is the mainstay of treatment for patients with localised disease and is often curative. However, as recurrence is likely to occur when tumour cells remain after surgery, adjuvant radiotherapy is often also considered, especially for patients with intermediate or high-grade tumours. Radiotherapy, uses high energy rays to help cure cancers, is also often administered for patients in whom surgery is inappropriate or who decline surgery.1

For soft tissue sarcomas, the specialist healthcare professional may recommend radiotherapy to shrink sarcomas before surgery, help stop the sarcoma returning after surgery, to help slow the growth rate of advanced sarcomas and help relieve symptoms.

Discover classification of sarcomas by histopathology, look at prevalence and more by visiting the The Soft Tissue Sarcoma Knowledge Centre.


References

  1. . Clark MA, Fisher C et al. (2005) “Soft-tissue sarcomas in adults.” N Engl JMed 353(7): 701–11.

Clinical Case Studies

Mediastinal Mass: Bronchogenic Cyst

Respiratory Medicine & Allergy: Lung Cancer

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK

Case History
A 24-year-old woman was seen in the chest clinic with an eight-week history of cough with occasional sputum, fever and malaise. She also described an occasional nagging pain under her sternum and palpitations.

Smoking Cessation

Respiratory Medicine & Allergy: Lung Cancer

Suma Kumar, Guy's and St Thomas' NHS Foundation Trust, London, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
The wife and daughter of a patient you are treating for lung cancer are concerned about their risk of developing cancer. The wife is an ex-smoker having stopped six months ago.

Medical Videos

An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
Eribulin Trial Success
Eribulin Trial Success
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
HPV Vaccine
HPV Vaccine
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma

Recent Drug Updates

Medical Journal Abstracts on Oncology

Overexpression of periostin in stroma positively associated with aggressive prostate cancer

Tue 17 Mar 2015 -  Overexpression of periostin in stroma positively associated with aggressive prostate cancer

Background: Periostin is an important extracellular matrix protein involved in cell development and adhesion. Previously, we identified periostin to be up-regulated in aggressive prostate cancer ...

Improving Prediction of Prostate Cancer Recurrence using Chemical Imaging

Wed 04 Mar 2015 -  Improving Prediction of Prostate Cancer Recurrence using Chemical Imaging

Precise outcome prediction is crucial to providing optimal cancer care across the spectrum of solid cancers. Clinically-useful tools to predict risk of adverse events (metastases, recurrence), ...

Medical Images

Hematoxylin and eosin stain
Hematoxylin and eosin stain
Bronchogenic cyst
Bronchogenic cyst
Pulmonary nodule
Pulmonary nodule
Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis
Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC)
Amiodarone Pulmonary Toxicity
Amiodarone Pulmonary Toxicity
Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - chest radiograph
Sarcoidosis - chest radiograph

Clinical Guidelines

EAU Guidelines on Prostate Cancer

Aug 2014

The European Association of Urology (EAU) Guidelines Group for Prostate Cancer have prepared this..

... guidelines document to assist medical professionals assess the evidence-based management of prostate cancer (PCa). The multidisciplinary guidelines panel includes urologists, radiation oncologists, a medical oncologist, a radiologist and a pathologist.

Early and locally advanced breast cancer: Diagnosis and treatment

Jul 2014

This guideline offers best practice advice on the care of patients with early or locally advanced..

... breast cancer.

Online CME

Managing patients at risk of prostate cancer

After completing this module, you should know: How to advise men who are worried about prostate cancer, what information you should give them, and the treatment options available to men...

Prostate cancer: understanding the patient pathway and treatment options - in association with Prostate Cancer UK

After completing this module you should, regarding prostate cancer: Know what treatment options are available for each stage of the disease, be able to discuss the risks and benefits of...

Prostate cancer screening and the management of clinically localized disease

Learning outcomes: 1) Recognize who is at risk of prostate cancer; 2) Review the current recommendations on prostate cancer screening; 3) Recognize the harms associated with prostate cancer biopsy; 4)...

Clinical Trials

PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not? (PRECISION)

-31 days ago

This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy. Each participant will be ...

Evaluation of Clarity Ultrasound Guidance for Prostate Therapy (Clarity-Pro)

-1 days ago

Radiotherapy (RT) is an important treatment for prostate cancer with over 10,000 men receiving RT per year in the UK. Prostate RT aims to deliver radiation dose to the prostate to kill cancer cells ...

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