Oncology Topic Homepage

Prostate Cancer Learning Hub

,Prostate Cancer Learning Hub

Prostate cancer is the third most frequently diagnosed cancer in Europe and the most common cancer among European men,1 making it a major cause of morbidity. Risk factors for prostate cancer include, increasing age, genetic susceptibility, glucose intolerance and environmental factors.2

The Prostate Cancer Learning Hub has been designed with the busy healthcare professional in mind. The resource conveniently organises a range of up-to-date education content, reference materials and decision support tools, all focussing on prostate cancer.

The disease awareness section provides you with access to a Prostate Cancer Knowledge Centre, which has been developed to provide you with easy to digest best practice guidance for the treatment and management of patients with prostate cancer. In addition access to editorials of key journal publications, an events calendar, video channel, patient materials and interactive healthcare professionals tools are also available.

References

  1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403. EUCAN fact sheet. Estimated incidence, mortality & prevalence, 2012.
  2. Tewari R, Rajender S, Natu SM et al. Diet, obesity, and prostate health: are we missing the link? J Androl 2012;33:763-776.

     

Soft Tissue Sarcoma

Soft Tissue Sarcoma

Soft Tissue Sarcomas (STS) are malignant (cancerous) tumors that develop in tissues which connect, support, or surround other structures and organs of the body. Muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues are types of soft tissue.

Management of soft tissue sarcoma depends on the stage of disease and histological subtype.1 Surgery is the mainstay of treatment for patients with localised disease and is often curative. However, as recurrence is likely to occur when tumour cells remain after surgery, adjuvant radiotherapy is often also considered, especially for patients with intermediate or high-grade tumours. Radiotherapy, uses high energy rays to help cure cancers, is also often administered for patients in whom surgery is inappropriate or who decline surgery.1

For soft tissue sarcomas, the specialist healthcare professional may recommend radiotherapy to shrink sarcomas before surgery, help stop the sarcoma returning after surgery, to help slow the growth rate of advanced sarcomas and help relieve symptoms.

Discover classification of sarcomas by histopathology, look at prevalence and more by visiting the The Soft Tissue Sarcoma Knowledge Centre.


References

  1. . Clark MA, Fisher C et al. (2005) “Soft-tissue sarcomas in adults.” N Engl JMed 353(7): 701–11.

Anti-Infectives Knowledge Network CDI

,AIKN CDI

The Anti-Infectives Knowledge Network – Clostridium difficile infections (AIKN-CDI), an initiative by Astellas Pharma EMEA, shares the expertise and experience of thought leaders in the area of anti-infectives.

Recent content updates include:

  • Data presentations from the 35th International Symposium on Intensive Care and Emergency Medicine (ISICEM), held in Brussels, Belgium 17–20 March 2015
  • Data from the largest ever European clinician consensus report on Clostridium difficile infection
  • Updates from the European Commission following the event hosted by CDI Europe and the European Hospital and Healthcare Federation (HOPE) on healthcare-associated infections and Clostridium difficile infection

Also available – interactive annotated treatment guidelines for the management of Clostridium difficile infection.

Please remember to return often to read updated news, clinical insights, and essential information from the latest anti-infectives congresses.

March 2015 FDX/15/0024/EUb

Anti-Infectives Knowledge Network IFI

,AIKN IFI

The Anti-Infectives Knowledge Network – Invasive Fungal Infections (AIKN-IFI), an initiative by Astellas Pharma EMEA, assembles the experience and expertise of a number of thought leaders in the area of anti-infectives, with particular focus on invasive fungal infections.

This free resource is regularly updated with congress highlights, industry reports, policy changes, clinical guidelines and downloadable material (e.g. presentation slides) from major medical events.

The latest update to the AIKN-IFI is a summary of recent ESCMID-led recommendations into the prevention and management of infections in solid organ transplantation. These new recommendations are available in the guidelines section.

May 2015 MYC/15/0020/EUb

Clinical Case Studies

Amiodarone Pulmonary Toxicity

Respiratory Medicine & Allergy: Non granuloma interstitial lung disease

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK
Boris Lams, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK
Christopher Kosky, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London , UK

Case History
A 72-year-old woman presented to hospital with shortness of breath. Two years prior to presentation she had been commenced on amiodarone 200 mg a day for non-sustained ventricular tachycardia.

Sarcoidosis (Radiographic Stages II and III)

Respiratory Medicine & Allergy: Non granuloma interstitial lung disease

Richard Leach , Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
A 44-year-old black lady presented with an eight-month history of tiredness, rapidly progressive breathlessness and bilateral interstitial, perihilar shadowing on a chest radiograph (CXR). Non-caseating granulomas were detected in transbronchial biopsies consistent with a diagnosis of sarcoidosis.

Latest News

Medical Videos

Eribulin Trial Success
Eribulin Trial Success
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
HPV Vaccine
HPV Vaccine

Recent Drug Updates

Medical Journal Abstracts on Oncology

Cost-effectiveness of a behavioral intervention for persistent urinary incontinence in prostate cancer patients.

Wed 13 May 2015 -  Cost-effectiveness of a behavioral intervention for persistent urinary incontinence in prostate cancer patients.

Background: The aim of this study was to evaluate the cost-effectiveness of a behavioral intervention for urinary incontinence of prostate cancerpatients. Study subjects were either ...

Androgen receptor: acting in the three-dimensional chromatin landscape of prostate cancer cells

Wed 13 May 2015 -  Androgen receptor: acting in the three-dimensional chromatin landscape of prostate cancer cells

Androgen receptor (AR) acts as a hormone-controlled transcription factor that conveys the messages of both natural and synthetic androgens to the level of genes and gene programs. Defective AR ...

Medical Images

Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Bronchogenic cyst
Bronchogenic cyst
Sarcoidosis - chest radiograph
Sarcoidosis - chest radiograph
Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis
Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC)
Hematoxylin and eosin stain
Hematoxylin and eosin stain
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - radiograph showing interstitial shadowing
Pulmonary nodule
Pulmonary nodule
Amiodarone Pulmonary Toxicity
Amiodarone Pulmonary Toxicity

Clinical Guidelines

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

Apr 2015

The European Association of Urology (EAU) Guidelines Panel for Muscle-invasive and Metastatic..

... Bladder Cancer (MIBC) has prepared these guidelines to help urologists assess the evidence-based management of MIBC and to incorporate guideline recommendations into their clinical practice.

Guidelines for the Management of Tumour Lysis Syndrome in Adults and Children with Haematological Malignancies on Behalf of the British Committee for Standards in Haematology

Mar 2015

The objective of this guideline is to provide healthcare professionals with clear guidance on the..

... management of patients with tumour lysis syndrome (TLS). The guidance may not be appropriate to every patient and in all cases individual patient circumstances may dictate an alternative approach.

Online CME

Managing patients at risk of prostate cancer

After completing this module, you should know: How to advise men who are worried about prostate cancer, what information you should give them, and the treatment options available to men...

Prostate cancer: understanding the patient pathway and treatment options - in association with Prostate Cancer UK

After completing this module you should, regarding prostate cancer: Know what treatment options are available for each stage of the disease, be able to discuss the risks and benefits of...

Prostate cancer screening and the management of clinically localized disease

Learning outcomes: 1) Recognize who is at risk of prostate cancer; 2) Review the current recommendations on prostate cancer screening; 3) Recognize the harms associated with prostate cancer biopsy; 4)...

Clinical Trials

Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations

-32 days ago

Olaparib administered as monotherapy in the maintenance setting improves progression free survival compared to placebo in patients whose tumours carry loss of function (deleterious or suspected ...

PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not? (PRECISION)

Fri 01 May 2015

This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy. Each participant will be ...

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