Oncology Topic Homepage

Prostate Cancer Learning Hub

,Prostate Cancer Learning Hub

Prostate cancer is the third most frequently diagnosed cancer in Europe and the most common cancer among European men,1 making it a major cause of morbidity. Risk factors for prostate cancer include, increasing age, genetic susceptibility, glucose intolerance and environmental factors.2

The Prostate Cancer Learning Hub has been designed with the busy healthcare professional in mind. The resource conveniently organises a range of up-to-date education content, reference materials and decision support tools, all focussing on prostate cancer.

The disease awareness section provides you with access to a Prostate Cancer Knowledge Centre, which has been developed to provide you with easy to digest best practice guidance for the treatment and management of patients with prostate cancer. In addition access to editorials of key journal publications, an events calendar, video channel, patient materials and interactive healthcare professionals tools are also available.

References

  1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403. EUCAN fact sheet. Estimated incidence, mortality & prevalence, 2012.
  2. Tewari R, Rajender S, Natu SM et al. Diet, obesity, and prostate health: are we missing the link? J Androl 2012;33:763-776.

     

Soft Tissue Sarcoma

Soft Tissue Sarcoma

Soft Tissue Sarcomas (STS) are malignant (cancerous) tumors that develop in tissues which connect, support, or surround other structures and organs of the body. Muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues are types of soft tissue.

Management of soft tissue sarcoma depends on the stage of disease and histological subtype.1 Surgery is the mainstay of treatment for patients with localised disease and is often curative. However, as recurrence is likely to occur when tumour cells remain after surgery, adjuvant radiotherapy is often also considered, especially for patients with intermediate or high-grade tumours. Radiotherapy, uses high energy rays to help cure cancers, is also often administered for patients in whom surgery is inappropriate or who decline surgery.1

For soft tissue sarcomas, the specialist healthcare professional may recommend radiotherapy to shrink sarcomas before surgery, help stop the sarcoma returning after surgery, to help slow the growth rate of advanced sarcomas and help relieve symptoms.

Discover classification of sarcomas by histopathology, look at prevalence and more by visiting the The Soft Tissue Sarcoma Knowledge Centre.


References

  1. . Clark MA, Fisher C et al. (2005) “Soft-tissue sarcomas in adults.” N Engl JMed 353(7): 701–11.

Clinical Case Studies

Mediastinal Mass: Bronchogenic Cyst

Respiratory Medicine & Allergy: Lung Cancer

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK

Case History
A 24-year-old woman was seen in the chest clinic with an eight-week history of cough with occasional sputum, fever and malaise. She also described an occasional nagging pain under her sternum and palpitations.

Smoking Cessation

Respiratory Medicine & Allergy: Lung Cancer

Suma Kumar, Guy's and St Thomas' NHS Foundation Trust, London, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
The wife and daughter of a patient you are treating for lung cancer are concerned about their risk of developing cancer. The wife is an ex-smoker having stopped six months ago.

Medical Videos

An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
Eribulin Trial Success
Eribulin Trial Success
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
HPV Vaccine
HPV Vaccine
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma

Recent Drug Updates

Medical Journal Abstracts on Oncology

Cigarette smoking during external beam radiation therapy for prostate cancer is associated with an increased risk of prostate cancer-specific mortality and treatment-related toxicity

Thu 23 Oct 2014 -  BJU International

Purpose: To evaluate whether a history of smoking or smoking during therapy after external beam radiotherapy (EBRT) for clinically localized prostate cancer is associated with increased ...

The outcome of cryoablation in treating advanced pancreatic cancer: A comparison with palliative bypass surgery alone

Thu 16 Oct 2014 -  Journal of Digestive Diseases

Objective: This study aimed to investigate the efficacy and safety of palliative bypass surgery combined with cryoablation in treating patients with advanced pancreatic cancer and compare this ...

Medical Images

Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Sarcoidosis - chest radiograph
Sarcoidosis - chest radiograph
Bronchogenic cyst
Bronchogenic cyst
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - radiograph showing interstitial shadowing
Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis
Hematoxylin and eosin stain
Hematoxylin and eosin stain
Amiodarone Pulmonary Toxicity
Amiodarone Pulmonary Toxicity
Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC)
Pulmonary nodule
Pulmonary nodule

Online CME

Clinical Review - Acoustic neuroma

This activity covers the diagnosis and management of acoustic neuroma.

Diagnosing osteosarcomas and brain tumours in children: communication skills - in association with the Department of Health

Diagnosing osteosarcomas and brain tumours in children: communication skills - in association with the Department of Health. For GPs, GP trainees, Foundation doctors.

Chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in adults in the Western world. About three quarters of patients diagnosed with chronic lymphocytic leukaemia are over 55 years old....

Clinical Trials

OSCA - Olaparib Standard of CAre Study

06-10-2014

This study will be carried out as a retrospective, non-interventional observational review of medical records for patients in multiple countries with platinum-sensitive recurrent serous ovarian cancer. The objectives are to describe in a real-world..

... population, treatment patterns, BRCA mutation testing and results, overall survival, health care utilization and also to estimate rates of selected treatment- and/or disease-related side effects

A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Patients With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma

02-10-2014

This study is a multicenter, open-label study of polatuzumab vedotin administere d by intravenous (IV) infusion in combination with standard doses of bendamustin e (B) and rituximab (R) or obinutuzumab (G) in patients with relapsed or refract ory..

... follicular lymphoma (FL) or diffuse large B-cell lymphoma (DLBCL). The study comprises two stages: a Phase 1b dose-escalation stage and a Phase 2 stage. The anticipated time on treatment is 18-24 weeks.

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