Oncology Topic Homepage

Learning Zones

,CLL Knowledge Centre and CME

The CLL Knowledge Centre and CME provide healthcare professionals with important information to aid the treatment and management of patients with the disease. Content is arranged within four main areas: Disease awareness, Events, Resources and CME.

Healthcare professionals will find sections on pathophysiology, signs and symptoms of CLL, diagnosis, prognosis, treatment, management, an upcoming events calendar and useful external links.

The CME activity ‘Treatment Optimisation in Chronic Lymphocytic Leukaemia’ allows you to read case studies and improve your knowledge of CLL by answering quiz questions based on a variety of scenarios. This module has been EACCME-accredited and is worth 1 European CME credit. There is no cost to complete this educational activity.

,Prostate Cancer Learning Hub

Prostate cancer is the third most frequently diagnosed cancer in Europe and the most common cancer among European men,1 making it a major cause of morbidity. Risk factors for prostate cancer include, increasing age, genetic susceptibility, glucose intolerance and environmental factors.2

The Prostate Cancer Learning Hub has been designed with the busy healthcare professional in mind. The resource conveniently organises a range of up-to-date education content, reference materials and decision support tools, all focussing on prostate cancer.

The disease awareness section provides you with access to a Prostate Cancer Knowledge Centre, which has been developed to provide you with easy to digest best practice guidance for the treatment and management of patients with prostate cancer. In addition access to editorials of key journal publications, an events calendar, video channel, patient materials and interactive healthcare professionals tools are also available.

References

  1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403. EUCAN fact sheet. Estimated incidence, mortality & prevalence, 2012.
  2. Tewari R, Rajender S, Natu SM et al. Diet, obesity, and prostate health: are we missing the link? J Androl 2012;33:763-776.

     

Clinical Case Studies

Mediastinal Mass: Bronchogenic Cyst

Respiratory Medicine & Allergy: Lung Cancer

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK

Case History
A 24-year-old woman was seen in the chest clinic with an eight-week history of cough with occasional sputum, fever and malaise. She also described an occasional nagging pain under her sternum and palpitations.

Pulmonary Nodules

Respiratory Medicine & Allergy: Lung Cancer

Burhan Khan, Consultant Respiratory Physician, Darent Valley Hospital, Dartford and Gravesham NHS Trust, Dartford, Kent, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust , London, UK

Case History
51-year-old man presented with a six-month history of paroxysmal cough following a viral upper respiratory tract infection. Apart from an episode of pneumonia as a child he had no other significant medical history, no allergies and he was on no medications.

Latest News

Blog

Overdiagnosis is the diagnosis of disease that will cause neither morbidity nor mortality during a patient’s lifetime. Doctors are trained to listen, examine, test, diagnose and treat patients, but we are not warned of the possible dangers of “diseases”, the diagnosis of which will not benefit the patient and may also lead to harm. I would argue the Hippocratic oath, in particular “Primum non nocere” (first, do no harm) should be at the forefront of every clinician’s mind when seeing patients. 

In this blog, I shall outline precisely what overdiagnosis is, why it is important and why we all need to take note of this crisis in healthcare. 

Medical Videos

Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Eribulin Trial Success
Eribulin Trial Success
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
HPV Vaccine
HPV Vaccine
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma

Recent Drug Updates

Medical Journal Abstracts on Oncology

Imatinib: a breakthrough of targeted therapy in cancer.

-15 days ago -  Imatinib: a breakthrough of targeted therapy in cancer.

Deregulated protein tyrosine kinase activity is central to the pathogenesis of human cancers. Targeted therapy in the form of selective tyrosine kinase inhibitors (TKIs) has transformed the approach ...

Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

5 days ago -  Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

Background: Ixazomib is an oral proteasome inhibitor that is currently being studied for the treatment of multiple myeloma. Methods: In this double-blind, placebo-controlled, phase 3 trial, we ...

Medical Images

Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - radiograph showing interstitial shadowing
Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Sarcoidosis - chest radiograph
Sarcoidosis - chest radiograph
Bronchogenic cyst
Bronchogenic cyst
Hematoxylin and eosin stain
Hematoxylin and eosin stain
Amiodarone Pulmonary Toxicity
Amiodarone Pulmonary Toxicity
Pulmonary nodule
Pulmonary nodule
Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC)

Clinical Guidelines

Myeloma: diagnosis and management

Feb 2016

This guideline covers the diagnosing and managing of myeloma (including smouldering myeloma and..

... primary plasma cell leukaemia) in people aged 16 and over. It aims to improve care for people with myeloma by promoting the most effective tests and treatments for myeloma and its complications.

This guideline includes recommendations on:
   - communication and support
   - laboratory investigations
   - imaging investigations
   - managing newly-diagnosed and relapsed myeloma
   - preventing and managing bone disease and other complications
   - monitoring

Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over

Feb 2016

This guideline covers assessing and managing cancers of the upper aerodigestive tract in young..

... people (aged 16 and over) and adults. It aims to reduce variation in practice and improve survival.

Recommendations
    - information and support
    - investigation
    - treatment of early and advanced stage disease
    - HPV-related disease
    - less common upper aerodigestive tract cancers
    - optimising rehabilitation and function
    - follow-up and treatment of late effects

Online CME

Treatment Optimisation in Chronic Lymphocytic Leukaemia

A new CME activity ‘Treatment Optimisation in Chronic Lymphocytic Leukaemia’ has been added to the CLL Knowledge Centre on epgonline.org. Read case studies and improve your knowledge of CLL by...

Challenges and Best Practices in the Use of Radionuclide Therapy in mCRPC

This activity is intended for radiation oncologists, medical oncologists, nuclear medicine specialists, urologists, and other clinicians who comprise the team of interprofessionals caring for men with metastatic castration-resistant prostate cancer....

Managing the side effects of treatment for prostate cancer - in association with Prostate Cancer UK

"After you have completed this module you should: Know what the acute and chronic side effects of treatment for prostate cancer are Understand why side effects occur Know how to...

Clinical Trials

Oral THU-Decitabine + Nivolumab for Advanced Non-Small Cell Lung Cancer

-58 days ago

This study looks at the effect of three drugs on lung cancer tumors. This study includes two groups of patients randomized to either Nivolumab, which is the standard of care for this lung cancer, or ...

A Trial to Evaluate Pemetrexed Clinical Responses in Relation to Tumor MTAP Gene Status in Patients With Previously Treated Metastatic Urothelial Carcinoma

-28 days ago

The goal of this clinical research study is to learn if Alimta (pemetrexed) can help to control urothelial cancer. The safety of this drug will also be studied. Researchers will also study how a ...

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