Oncology Topic Homepage

Prostate Cancer Learning Hub

,Prostate Cancer Learning Hub

Prostate cancer is the third most frequently diagnosed cancer in Europe and the most common cancer among European men,1 making it a major cause of morbidity. Risk factors for prostate cancer include, increasing age, genetic susceptibility, glucose intolerance and environmental factors.2

The Prostate Cancer Learning Hub has been designed with the busy healthcare professional in mind. The resource conveniently organises a range of up-to-date education content, reference materials and decision support tools, all focussing on prostate cancer.

The disease awareness section provides you with access to a Prostate Cancer Knowledge Centre, which has been developed to provide you with easy to digest best practice guidance for the treatment and management of patients with prostate cancer. In addition access to editorials of key journal publications, an events calendar, video channel, patient materials and interactive healthcare professionals tools are also available.

References

  1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer 2013;49:1374-1403. EUCAN fact sheet. Estimated incidence, mortality & prevalence, 2012.
  2. Tewari R, Rajender S, Natu SM et al. Diet, obesity, and prostate health: are we missing the link? J Androl 2012;33:763-776.

     

Soft Tissue Sarcoma

Soft Tissue Sarcoma

Soft Tissue Sarcomas (STS) are malignant (cancerous) tumors that develop in tissues which connect, support, or surround other structures and organs of the body. Muscles, tendons (bands of fiber that connect muscles to bones), fibrous tissues, fat, blood vessels, nerves, and synovial tissues are types of soft tissue.

Management of soft tissue sarcoma depends on the stage of disease and histological subtype.1 Surgery is the mainstay of treatment for patients with localised disease and is often curative. However, as recurrence is likely to occur when tumour cells remain after surgery, adjuvant radiotherapy is often also considered, especially for patients with intermediate or high-grade tumours. Radiotherapy, uses high energy rays to help cure cancers, is also often administered for patients in whom surgery is inappropriate or who decline surgery.1

For soft tissue sarcomas, the specialist healthcare professional may recommend radiotherapy to shrink sarcomas before surgery, help stop the sarcoma returning after surgery, to help slow the growth rate of advanced sarcomas and help relieve symptoms.

Discover classification of sarcomas by histopathology, look at prevalence and more by visiting the The Soft Tissue Sarcoma Knowledge Centre.


References

  1. . Clark MA, Fisher C et al. (2005) “Soft-tissue sarcomas in adults.” N Engl JMed 353(7): 701–11.

Anti-Infectives Knowledge Network CDI

,AIKN CDI

The Anti-Infectives Knowledge Network – Clostridium difficile infections (AIKN-CDI), an initiative by Astellas Pharma EMEA, shares the expertise and experience of thought leaders in the area of anti-infectives.

Recent content updates include:

  • Presentation slides from recent congresses including ECCMID, EBMT and ISICEM 2015
  • News articles from key industry thinkers located within the ‘CDI perspectives’ section
  • An animation sequence showing gut microflora and the effects of antibiotics on CDI
  • Opportunity to participate in the second round of the largest ever clinician consensus report through completing a questionnaire. Subsequent recommendations will be made based on the data collected from this questionnaire

Please remember to return often to read updated news, clinical insights, and essential information from the latest congresses.

May 2015 MYC/15/0020/EUb

Anti-Infectives Knowledge Network IFI

,AIKN IFI

The Anti-Infectives Knowledge Network – Invasive Fungal Infections (AIKN-IFI), an initiative by Astellas Pharma EMEA, assembles the experience and expertise of a number of thought leaders in the area of anti-infectives, with particular focus on invasive fungal infections.

This free resource is regularly updated with congress highlights, industry reports, policy changes, clinical guidelines and downloadable material (e.g. presentation slides) from major medical events.

The latest update to the AIKN-IFI is a summary of recent ESCMID-led recommendations into the prevention and management of infections in solid organ transplantation. These new recommendations are available in the guidelines section.

May 2015 MYC/15/0020/EUb

Clinical Case Studies

Sarcoidosis (Radiographic Stages II and III)

Respiratory Medicine & Allergy: Non granuloma interstitial lung disease

Richard Leach , Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
A 44-year-old black lady presented with an eight-month history of tiredness, rapidly progressive breathlessness and bilateral interstitial, perihilar shadowing on a chest radiograph (CXR). Non-caseating granulomas were detected in transbronchial biopsies consistent with a diagnosis of sarcoidosis.

Mediastinal Mass: Bronchogenic Cyst

Respiratory Medicine & Allergy: Lung Cancer

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK

Case History
A 24-year-old woman was seen in the chest clinic with an eight-week history of cough with occasional sputum, fever and malaise. She also described an occasional nagging pain under her sternum and palpitations.

Latest News

Medical Videos

Eribulin Trial Success
Eribulin Trial Success
An Overview of Pancreatic NET and the Available Treatments
An Overview of Pancreatic NET and the Available Treatments
Surviving Advanced Breast Cancer
Surviving Advanced Breast Cancer
New Developments in the Treatment of Breast Cancer
New Developments in the Treatment of Breast Cancer
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
In the podcast, Dr. Crawford describes current and upcoming options available to urologists for treating this group of patients.
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
Metastatic Breast Cancer - A Patient's View of Various Treatments Including Eribulin
HPV Vaccine
HPV Vaccine
Cancer Vaccines- Dr. Kelvin Lee
Cancer Vaccines- Dr. Kelvin Lee
An Animation Explaining the Development of Lymphoma
An Animation Explaining the Development of Lymphoma

Recent Drug Updates

Medical Journal Abstracts on Oncology

Circulating tumor cell biomarker panel as an individual-level surrogate for survival in metastatic castration-resistant prostate cancer.

Tue 23 Jun 2015 -  Circulating tumor cell biomarker panel as an individual-level surrogate for survival in metastatic castration-resistant prostate cancer.

Purpose: Trials in castration-resistant prostate cancer (CRPC) need new clinical end points that are valid surrogates for survival. We evaluated circulating tumor cell (CTC) enumeration ...

Cognitive existential couple therapy (CECT) in men and partners facing localised prostate cancer: a randomised controlled trial.

Tue 23 Jun 2015 -  Cognitive existential couple therapy (CECT) in men and partners facing localised prostate cancer: a randomised controlled trial.

Objectives: To assess the efficacy of cognitive existential couple therapy (CECT) for relationship function, coping, cancer distress and mental health in men with ...

Medical Images

Small Cell Lung Cancer (SCLC)
Small Cell Lung Cancer (SCLC)
Bronchogenic cyst
Bronchogenic cyst
Sarcoidosis - radiograph showing interstitial shadowing
Sarcoidosis - radiograph showing interstitial shadowing
Amiodarone Pulmonary Toxicity
Amiodarone Pulmonary Toxicity
Sarcoidosis - chest radiograph
Sarcoidosis - chest radiograph
Hematoxylin and eosin stain
Hematoxylin and eosin stain
Pulmonary nodule
Pulmonary nodule
Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer (NSCLC)
Hypersensitivity Pneumonitis
Hypersensitivity Pneumonitis

Clinical Guidelines

Guidelines on Muscle-invasive and Metastatic Bladder Cancer

Apr 2015

The European Association of Urology (EAU) Guidelines Panel for Muscle-invasive and Metastatic..

... Bladder Cancer (MIBC) has prepared these guidelines to help urologists assess the evidence-based management of MIBC and to incorporate guideline recommendations into their clinical practice.

Guidelines for the Management of Tumour Lysis Syndrome in Adults and Children with Haematological Malignancies on Behalf of the British Committee for Standards in Haematology

Mar 2015

The objective of this guideline is to provide healthcare professionals with clear guidance on the..

... management of patients with tumour lysis syndrome (TLS). The guidance may not be appropriate to every patient and in all cases individual patient circumstances may dictate an alternative approach.

Online CME

Managing patients at risk of prostate cancer

After completing this module, you should know: How to advise men who are worried about prostate cancer, what information you should give them, and the treatment options available to men...

Prostate cancer: understanding the patient pathway and treatment options - in association with Prostate Cancer UK

After completing this module you should, regarding prostate cancer: Know what treatment options are available for each stage of the disease, be able to discuss the risks and benefits of...

Prostate cancer screening and the management of clinically localized disease

Learning outcomes: 1) Recognize who is at risk of prostate cancer; 2) Review the current recommendations on prostate cancer screening; 3) Recognize the harms associated with prostate cancer biopsy; 4)...

Clinical Trials

Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations

4 days ago

Olaparib administered as monotherapy in the maintenance setting improves progression free survival compared to placebo in patients whose tumours carry loss of function (deleterious or suspected ...

PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not? (PRECISION)

Fri 01 May 2015

This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy. Each participant will be ...

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