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April 2008 News
- Clinical news: Genentech, Biogen Idec say Rituxan study fails to meet endpoints
Rituxan (rituximab) has failed to meet the primary endpoint in a Phase II/III trial involving patients with systemic lupus erythematosus (SLE), Genentech and Biogen Idec have announced. The...
Published Wednesday 30 April 2008 - CACS indicate likelihood of cardiovascular events in type 2 diabetes
High coronary artery calcification scores (CACS) may indicate an increased risk of cardiovascular events in patients with type 2 diabetes, research claims. The findings, reported by DGDispatch, were...
Published Wednesday 30 April 2008 - Parkinson's disease: Spheramine 'well-tolerated'
A novel cell therapy using retinal pigment epithelial (ROE) cells attached to gelatine bead microcarriers implanted in the brain appears to improve moderate to advanced Parkinson's disease symptoms....
Published Tuesday 29 April 2008 - Pharmaceutical industry news: Angiotensin II receptor antagonists' safety in early pregnancy questioned
Product information for all centrally authorised angiotensin II receptor antagonists must be altered to reflect safety concerns regarding their use during pregnancy, the European Medicines Agency (EMEA) has...
Published Monday 28 April 2008 - Disease specific news: EU gives backing to hepatitis B Viread
The European Commission has given its approval to the marketing of Viread (tenofovir disoproxil fumarate) as a treatment for chronic hepatitis B. Viread has received approval for use...
Published Monday 28 April 2008 - UK trial: Uptake of HPV vaccine 'encouraging'
A study to assess the feasibility and acceptability of delivering a human papillomavirus vaccine to adolescent girls has resulted in 'encouraging' results. The prospective cohort study, published in...
Published Friday 25 April 2008 - Pharmaceutical industry news: EU application for Tygacil withdrawn
Wyeth has announced the withdrawal of an application to expand EU authorisation of antibiotic Tygacil (tigecycline) to include community-acquired pneumonia. The move comes after the European Medicines Agency...
Published Friday 25 April 2008 - Sweden: Dutasteride plus Tamsulosin approved for BPH
Dutasteride (Avodart) in combination with tamsulosin for the treatment of patients with moderate to severe benign prostatic hyperplasia (BPH) has been given approval in Sweden. Approval for the...
Published Thursday 24 April 2008 - Disease specific news: VAP, ARDS patients display no added mortality risk
There appears to be no association between mortality and ventilator-associated pneumonia (VAP) among patients with trauma or acute respiratory distress syndrome (ARDS), a study claims. It is believed...
Published Thursday 24 April 2008 - Pharmaceutical Industry News: Novartis lowers Coartem price
Novartis has announced it is to lower the price of malaria drug Coartem (artemether/lumefantrine) by an average of 20 per cent. In a statement the drug manufacturer cited...
Published Thursday 24 April 2008 - Pharmaceutical industry news: Combination drug for essential hypertension given EU backing
European marketing authorisation has been granted for the antihypertensive fixed-dose combination drug 80 mg telmisartan/25 mg hydrochlorothiazide (T80/H25). Marketed as PritorPlus 80/25 and Kinzalkomb 80/25, the formulation will...
Published Wednesday 23 April 2008 - ADHD heart tests 'should precede stimulant drug treatment'
Patients with attention deficit hyperactivity disorder (ADHD) should receive cardiac evaluation prior to treatment with stimulant medication, experts state. The statement by the American Heart Association (AHA) follows...
Published Wednesday 23 April 2008 - Sumatriptan, naproxen combination offers 'significant' headache relief
A combination of anti-migraine drug sumatriptan and NSAID naproxen appears to aid headache pain for 24 hours without adverse events better than placebo. Findings were presented at the...
Published Tuesday 22 April 2008 - Disease specific news: Herceptin prior to surgery eradicates HER2-positive breast tumours
Herceptin (trastuzumab) in combination with chemotherapy before surgery helps to eradicate HER2-positive breast tumours, research suggests. Drug maker Roche announced the results of the Phase III study presented...
Published Tuesday 22 April 2008 - Barbiturate, opioid use linked to chronic migraine
Users of barbiturates and opioids to treat migraine appear to be at an increased risk of developing a chronic form of the condition. A study questioned 24,000 people...
Published Saturday 19 April 2008 - Pharmaceutical industry news: AstraZeneca patent dispute settled
AstraZeneca has announced that it has entered into an agreement to settle a patent infringement litigation against Ranbaxy Laboratories. Legal action involving Ranbaxy and AstraZeneca has been ongoing...
Published Thursday 17 April 2008 - Parkinson's disease: Entacapone addition improves levodopa/carbidopa benefit
Levodopa/carbidopa/entacapone (LCE) appears to improve symptoms of Parkinson's disease in its early stages more than levodopa/carbidopa (LC), a study suggests. Findings reported at the American Academy of Neurology...
Published Thursday 17 April 2008 - Anti-cholesterol statins linked to blood pressure reduction
Statins prescribed for high cholesterol appear to result in a "modest but significant" reduction in blood pressure, a report claims. A double-blind placebo-controlled study was carried out on...
Published Wednesday 16 April 2008 - Clinical news: Experimental breast cancer vaccine 'reduces death risk'
An experimental treatment designed to stimulate the immune system to fight breast cancer appears to reduce the risk of death by half, a study shows. Research conducted by...
Published Tuesday 15 April 2008 - Disease-specific news: Vitamin analogue MC-1 appears not to provide benefits to heart surgery patients
Investigative drug MC-1 provides no added benefit for patients undergoing coronary artery bypass graft (CABG) surgery, researchers have claimed. Findings presented at the American College of Cardiology 57th...
Published Tuesday 15 April 2008 - Pharmaceutical industry news: Novartis late-stage trial for NSCLC drug
Novartis AG has announced the start of a late-stage trial for its ASA404 drug in the treatment of lung cancer. The launch of the Phase III Antivascular Targeted...
Published Saturday 12 April 2008 - Mid-life diabetes linked to Alzheimer's disease risk
Men who develop diabetes in mid-life appear to have a greater risk of developing Alzheimer's disease. A long-term study in Sweden followed 2,269 men who were tested at...
Published Saturday 12 April 2008 - Disease specific news: Gene variant increases asthma risk
A variation in the CHI3L1 gene increases susceptibility to asthma, bronchial hyper-responsiveness and decline in lung function, a study claims. Researchers studied a genetically isolated population, the Hutterites...
Published Saturday 12 April 2008 - Disease related news: Omega-3 free fatty acids 'do not prevent Crohn's disease relapse'
Omega-3 free fatty acids supplements do not appear to prevent relapse in Crohn's disease patients, a study shows. A team at the University of Western Ontario conducted two...
Published Thursday 10 April 2008 - Pharmaceutical industry news: EC approves aripiprazole for bipolar I disorder
The European Commission (EC) has granted marketing approval for aripiprazole (Abilify) for the treatment of moderate to severe manic episodes in bipolar I disorder. The approval for the...
Published Thursday 10 April 2008 - Parkinson's Disease: Foetal cells may not function long term
Neurons grafted onto a Parkinson's disease (PD) patient 14 years ago have developed Lewy body pathology, it has been reported. The research published in Nature Medicine appears to...
Published Thursday 10 April 2008 - Pharmaceutical industry news: Forsteo approved by European Commission
Eli Lilly has received approval from the European Commission for Forsteo to be used in the treatment of glucocorticoid induced osteoporosis (GIOP). The drugs maker announced that approval...
Published Tuesday 08 April 2008 - Disease related news: Diagnostic test for Alzheimer's disease to be launched
A diagnostic test designed to give early diagnosis of neurodegenerative diseases including Alzheimer's and Parkinson's disease could be launched in Europe by this summer. The test, NuroPro, could...
Published Tuesday 08 April 2008 - Diabetes stem cell discovery
Embryonic stem cells have been turned into insulin-producing pancreatic tissue using a new technique. Researchers from the Universities of Manchester and Sheffield genetically manipulated stem cells to produce...
Published Saturday 05 April 2008 - Pioglitazone appears to prevent atherosclerosis in type 2 diabetes patients
Pioglitazone may prevent the progression of atherosclerosis in patients with type 2 diabetes, findings suggest. A study compared the effects of two classes of oral hypoglycaemic agents on...
Published Friday 04 April 2008 - ADHD stimulant link to substance abuse 'unlikely'
Children treated with stimulants for attention deficit hyperactivity disorder (ADHD) at ages six and seven are unlikely to demonstrate increased risk of substance abuse as adults. A study...
Published Friday 04 April 2008 - Calcium channel blockers effective antihypertensive therapy in osteoarthritis
Antihypertensive effects of calcium channel blockers (CCB) do not diminish when taken in conjunction with anti-inflammatory drug (NSAID) therapy in osteoarthritis patients, a study suggests. CCBs were also...
Published Thursday 03 April 2008 - High blood pressure-lowering treatment shows reduced mortality in elderly
Elderly patients given a diuretic indapamide slow release 1. 5 mg with the ACE inhibitor perindopril in tablet form once per day appear to show reduced mortality rates...
Published Thursday 03 April 2008 - Pharmaceutical industry news: Taranabant appears to significantly aid weight loss
Patients taking Merck & Co's experimental obesity drug taranabant experienced statistically significant weight loss, it has been reported. The drug maker presented 52-week findings from a phase II...
Published Wednesday 02 April 2008 - Study questions neuroleptic drug effectiveness in Alzheimer's patients
A UK study appears to show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in Alzheimer's patients. A randomised, blinded placebo-controlled trial analysed 165 patients...
Published Wednesday 02 April 2008 - Sexual dysfunction in women increased by LUTS
Lower urinary tract symptoms (LUTS) appear to increase rates of sexual dysfunction in women. Research has previously been undertaken into the condition in male sexual disorders yet knowledge...
Published Wednesday 02 April 2008 - Gene findings show diabetes prostate cancer link
Research has offered up six further genetic variants involved in type 2 diabetes, with one of these new variants also appearing to be implicated as a cause of...
Published Wednesday 02 April 2008
