Ixazomib (Takeda/Millennium) enters Phase III trials for Multiple Myeloma - 05-Jul-2012

Takeda and Millennium Oncology have begun a Phase III development programme for ixazomib citrate (MLN 9708), the first oral proteasome inhibitor to enter clinical trials for Multiple Myeloma and to be a possible successor to the Velcade. The trial is TOURMALINE-MM1 which will assess MLN 9708 in patients with relapsed and/or refractory Multiple Myeloma at sites in North and South America, Europe and the Asia-Pacific region. A once weekly dose will be administered in combination with lenalidomide and dexamethasone therapy and compared with placebo plus the latter two drugs against the primary endpoint of progression-free survival.Ixazomib has improved and broader activity and pharmacokinetics compared with Velcade which is intravenously administered whereas Ixazomib is orally administered.

Related News

Back to top

Latest News

18 Nov 2014
17 Nov 2014
17 Nov 2014