NICE positive for Procoralan (Servier) for Heart Failure - 24-Oct-2012
The National Institute for Health and Clinical Excellence (NICE) has now published final draft guidance recommending Procoralan (ivabradine) from Servier Labs, as an option for treating Chronic Heart Failure, specified as NYHA class II to IVi. It has, however, stipulated that the drug should only be used in patients with systolic dysfunction, those who are in sinus rhythm, when the heart rate is 75 beats per minute or more, and for those who have a left ventricular ejection fraction of 35% or less.
The draft guidelines also state that Procoralan should be taken with standard therapy, such as including beta-blockers or angiotensin-converting enzyme (ACE) inhibitors, or when a patient is unable to take/tolerate beta-blockers.
Related News
FDA approves Viva and Evera defibrillators for Heart Failure
Phase II study of CQR 1 (Cardio3Biosciences) published in Journal of the American College of Cardiology
Phase III trial of Aranesp (Amgen) in anemic Heart Failure patients shows drug offers no real benefit
Xarelto enters Phase III trial for Heart Failure and CAD
EU approves Ilesto 7 (Biotronik) for patients with Heart Failure
Aranesp (Amgen) fails Heart Failure trial
EU awards CE mark to Revivent Myocardial Anchoring System (BioVentrix) for Heart Failure patients
RELAX-AF trial positive for serelaxin (Novartis) for Acute Heart Failure
Related Cardiology Information
Cardiology Clinical Guidelines
Atrial fibrillation: National clinical guideline for management in primary and secondary care
NICEHypertension: management of hypertension in adults in primary care
NICECardiology Clinical Trials
A Pilot Study of a Novel Technique for Cardiac Resynchronisation Therapy to Treat Heart Failure (LV-CONSEPT)
Clinicaltrials.gov 19 March 2013A Study to Assess the Pharmacokinetics and Pharmacodynamics of JNJ-54452840 in Participants With Heart Failure and Anti-beta1-adrenergic Receptor Autoantibodies
Clinicaltrials.gov 22 February 2013Cardiology Medical Journal Abstracts
Local Versus Epidural Anesthesia in Fast-Track Abdominal Aortic Surgery
Journal of Cardiothoracic and Vascular Anesthesia 02 January 2013β-Blockers and Volatile Anesthetics May Attenuate Cardioprotection by Remote Preconditioning in Adult Cardiac Surgery: A Meta-analysis of 15 Randomized Trials
Journal of Cardiothoracic and Vascular Anesthesia 02 January 2013Cardiology Medical Apps
Cardiac CT imaging - Diagnosis of Cardiovascular disease
£3.99
Cardio3 ECHO Lite
Free
Related Cardiology Drugs
- HELIXATE
- NATRILIX SR
- CORDARONE X INTRAVENOUS
- APRESOLINE AMPOULES 20 MG
- LASIX INJECTION 20MG/2ML
- BEZALIP 200MG TABLETS
- LOPRESOR (HYPERTENSION)
- TARKA
- SIMVADOR 10MG, 20MG, 40MG, 80MG
- TENSIPINE MR
- HEPARIN CALCIUM 25,000 I.U./ML SOLUTION FOR INJECTION OR CONCENTRATE FOR SOLUTION FOR INFUSION
- TRASIDREX
- BISOPROLOL 2.5MG/5MG/10MG FILM COATED TABLET
- COVERSYL ARGININE PLUS TABLETS
- NAVISPARE
- HYPOLOC 5 MG TABLETS
- ZOCOR 10MG, 20MG, 40MG AND 80MG FILM-COATED TABLETS
- GRANOCYTE
- RAMIPRIL 10MG TABLETS
- SPIRONOLACTONE 100MG TABLETS
- TENORMIN LS 50MG TABLETS
- AMIODARONE 200MG TABLETS
- CATAPRES TABLETS 100MCG
- OPTISON
- NYOGEL 0.1% EYE GEL
- FRUSENE
- SLOW TRASICOR
- RANEXA PROLONGED-RELEASE TABLETS
- SIMVASTATIN 40MG
- TENORMIN INJECTION 0.5MG/ML
- CANDESARTAN CILEXETIL 16 MG TABLETS
- LISINOPRIL 10MG TABLETS
- ADRENALINE [EPINEPHRINE] 1 IN 1,000
- GLYCERYL TRINITRATE
- TOREM
- ARYTHMOL
- ADIPINE MR
- TELMISARTAN ACTAVIS 20 MG TABLETS
- CLIVARINE
- FERROUS SULPHATE TABLETS, COMPOUND
- INDOCID PDA
- LIPOBAY
- MEXITIL
- PRIMACOR 1MG/ML SOLUTION FOR INJECTION
- FRU-CO
- SECTRAL 400MG TABLETS
- DOBUTAMINE 5 MG/ML, SOLUTION FOR INFUSION
- EMCOR
- SIMVASTATIN 20MG/5ML ORAL SUSPENSION
- NEBILET 5 MG TABLETS
- FERROUS SULPHATE ORAL SOLUTION
- LOPRESOR SR
- REFLUDAN 50 MG POWDER FOR SOLUTION FOR INJECTION OR INFUSION
- MODURETIC
- QUIXIDAR 2.5 MG/0.5 ML
- DEPONIT 5
- MONOZIDE 10
- ISIB
- REOPRO
- VIAZEM XL 120MG / 180MG / 240MG / 300MG / 360MG
- INDIPAM XL
- ISOSORBIDE MONONITRATE 20MG TABLETS
- CARDURA XL TABLETS
- DILZEM SR
- PERSANTIN RETARD 200 MG
- TENORETIC
- MINITRAN
- FIRAZYR SOLUTION FOR INJECTION
- SIMVASTATIN 10MG FILM-COATED TABLETS
- ELANTAN (HEART FAILURE)
- PERSANTIN 100 MG TABLETS
- INDERAL LA 160MG
- EZETROL TABLETS
- ZAPAIN
- AMIAS TABLETS
- PRITOR
- SOLIRIS SOLUTION FOR INFUSION
- ASASANTIN RETARD
- DIGOXIN INJECTION BP 500 MICROGRAMS/2ML
- PEDEA 5 MG/ML SOLUTION FOR INJECTION
- LANOXIN
- UNIVER 240MG PROLONGED RELEASE CAPSULES
- KERLONE
- LOPID 300MG HARD CAPSULES & 600MG FILM-COATED TABLETS
- NIMOTOP 0.02% SOLUTION FOR INFUSION
- TENORMIN SYRUP
- PERCUTOL
- ENALAPRIL MALEATE 5MG TABLETS
- SOLOC 5 MG TABLETS
- LASILACTONE
- CARACE (CARDIAC FAILURE)
- KALTEN
- CALCIUM CHLORIDE INTRAVENOUS INFUSION, 10% W/V
- SECURON SR
- NEORECORMON (SOLUTION FOR INJECTION)
- BEZALIP MONO / CALBERZOL XL
- TRITACE 2.5MG TABLETS
- HYDROSALURIC
- PRONESTYL
- MODURET 25
- LESCOL XL 80 MG PROLONGED RELEASE TABLETS
- ISMO RETARD
- DOBUTAMINE CONCENTRATE 250MG/20ML
- QUIXIDAR 1.5 ML/0.3 ML
- SEVIKAR
- EUCARDIC 25MG TABLETS
- CORACTEN XL (ANGINA)
- SIMVASTATIN 80MG
- ZANIDIP 20 MG TABLETS
- SLOZEM
- LERCANIDIPINE HYDROCHLORIDE 20 MG FILM-COATED TABLETS
- XIGRIS SOLUTION FOR INFUSION
- ISOKET INFUSION
- LOSARTAN POTASSIUM 50 MG FILM-COATED TABLETS
- NEUPOGEN
- REPLENINE
- FRUSOL
- CLOPIDOGREL 75 MG FILM-COATED TABLETS
- PERSANTIN AMPOULES 10 MG/2 ML SOLUTION FOR INFUSION
- CORDARONE 100MG AND 200MG TABLETS
- ISMELIN
- FERROUS GLUCONATE 300MG TABLETS
- OXPRENOLOL
- EPINEPHRINE (ADRENALINE) INJECTION 1:10,000
- DYTAC 50MG CAPSULES
- COLESTID
- DOPACARD
- ALDACTONE 25MG, 50MG AND 100MG TABLETS
- LOPRESOR (ANGINA)
- EXFORGE 5MG/80MG, 5MG/160MG, 10MG/160MG FILM COATED TABLETS
- LONITEN
- TILDIEM RETARD 90MG PROLONGED-RELEASE TABLETS, TILDIEM RETARD 120MG PROLONGED-RELEASE TABLETS
- CO-BETALOC
- CARDENE SR 30 AND 45MG
- ACCURETIC 10/12.5MG TABLETS
- ACTILYSE CATHFLO 2 MG
- NITROLINGUAL
- TRIAPIN
- STREPTASE 250,000 IU AND 750,000 IU
- METOPIRONE
- EUDEMINE (HYPERTENSION)
- EUCARDIC 12.5MG TABLETS
- HEXOPAL
- SUPRALIP 160
- APROVEL FILM-COATED TABLETS (SANOFI-AVENTIS BRISTOL-MYERS SQUIBB SNC)
- ARAMINE
- NEO-NACLEX
- BETA-ADALAT
- FRUMIL LS
- TRACLEER
- SINTHROME
- DIGOXIN TABLETS BP 62.5MCG, 125MCG, 250MCG
- HYDRALAZINE TABLETS
- TRANSIDERM-NITRO 5 AND 10
- CORGARD TABLETS 80MG
- FRAGMIN 10,000 IU/1 ML
- HYDRALAZINE AMPOULES
- AGGRASTAT
- ADALAT
- FLOLAN
- BETIM 10MG TABLETS
- ELANTAN LA (ANGINA)
- OPILON
- DIOVAN 40MG CAPSULES
- LISINOPRIL 2.5MG TABLETS
- INNOZIDE
- COZAAR 12.5 MG, 25 MG, 50 MG AND 100 MG FILM-COATED TABLETS
- ADALAT LA 20 MG PROLONGED-RELEASE TABLETS
- DIOVAN 320MG FILM-COATED TABLETS
- DEMSER
- CATAPRES TABLETS 300MCG
- COZAAR - COMP 50/12.5MG, 100/12.5MG AND 100/25MG FILM-COATED TABLETS
- COVERSYL ARGININE
- REVATIO 20 MG FILM-COATED TABLETS
- CARDICOR 1.25MG, 2.5MG, 3.75MG, 5MG, 7.5MG, 10MG FILM COATED TABLETS
- ATENOLOL 50MG FILM-COATED TABLETS
- ZEMTARD XL
- TEVETEN 300MG AND 600MG FILM-COATED TABLETS
- COZAAR 2.5 MG/ML POWDER AND SOLVENT FOR ORAL SUSPENSION
- EPHEDRINE HYDROCHLORIDE
- CHEMYDUR 60XL
- PERDIX
- MONOCOR
- REVASC
- ADCIRCA
- OCTANATE 100IU/ML
- ACTILYSE
- METENIX
- CARACE 20 PLUS TABLETS
- BEDRANOL 160MG SR CAPSULES
- ANGITIL SR /XL
- TRIAM-CO
- NEOSPECT
- HYTRIN
- AMIODARONE
- ANGETTES 75
- PLENDIL 2.5MG, PLENDIL 5MG AND PLENDIL 10MG
- ZESTORETIC
- SIMVASTATIN 40MG/5ML ORAL SUSPENSION
- LIPANTIL MICRO
- AMIODARONE 100MG TABLETS
- PLAVIX 75MG TABLETS
- TILDIEM LA 200/300MG PROLONGED-RELEASE CAPSULES
- NIMOTOP 30MG TABLETS
- TAMBOCOR XL CAPSULES
- BENDROFLUAZIDE
- DIUREXAN TABLETS
- CELECTOL 200 TABLETS
- GLYCERYL TRINITRATE INJECTION
- XISMOX 60 XL PROLONGED RELEASE TABLETS
- KABIKINASE
- TEKAMLO
- TRISENOX SOLUTION FOR INFUSION
- IMDUR
- ELANTAN (ANGINA)
- NU-SEALS 75
- INDEREX
- COAPROVEL
- VERTAB SR 240MG
- STROMBA
- ALDACTIDE 25MG AND 50MG TABLETS
- IMAZIN XL
- PHARMADREAMS - ENALAPRIL 20MG TABLETS
- TRANDATE TABLETS
- ADALAT 5
- UNIVER 120MG PROLONGED RELEASE CAPSULES
- TRENTAL 400
- AMLODIPINE 10MG TABLETS
- ROGITINE
- VISKEN TABLETS 5 MG
- NAVIDREX
- NITROCINE
- PRESCAL
- GLYTRIN
- BETALOC I.V. INJECTION
- NEPHRIL
- CARDENE 20 AND 30MG
- RAPISCAN (REGADENOSON)
- PAROVEN
- DIPYRIDAMOLE
- VENOFER
- TENIF
- INOSITOL NICOTINATE
- ADVATE SOLUTION FOR INJECTION
- SYTRON
- MONOMAX SR
- CO-AMILOFRUSE TABLETS 5/40MG
- MOTENS TABLETS
- CELIPROLOL
- CAPOTEN TABLETS 25 MG & 50 MG
- PROPRANOLOL
- BARATOL
- ACCUPRO TABLETS 5MG, 10MG, 20MG & 40MG
- FRUMIL
- VERAPAMIL (SVTS)
- DOPAMINE 40 MG/ML STERILE CONCENTRATE
- SUSCARD BUCCAL
- HAEMATE P 500 AND 1000 IU
- ADENOCOR
- ADIZEM-SR TABLETS
- MULTAQ 400MG TABLETS
- ATENOLOL 25MG TABLETS
- PREGADAY
- KOGENATE BAYER 500 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION (MEDIMOP)
- LIPOSTAT
- ACETAZOLAMIDE 250MG TABLETS
- AMLOSTIN 10MG
- CAPOZIDE TABLETS
- INNOVACE
- CAPTO-CO
- CELECTOL 400 TABLETS
- LISINOPRIL 20MG TABLETS
- ISOKET RETARD
- OLBETAM CAPSULES 250
- PRESTIM TABLETS
- ZESTRIL 2.5MG, 5MG, 10MG, AND 20MG TABLETS.
- SOTACOR TABLETS
- CRESTOR 5MG, 10MG, 20MG AND 40MG FILM-COATED TABLETS
- VISKEN TABLETS 15 MG
- EPINEPHRINE [ADRENALINE] 1 IN 10, 000
- HEPSAL
- VERAPAMIL (ANGINA)
- DISOPYRAMIDE
- CAPTOPRIL 12.5 MG, 25 MG AND 50 MG TABLETS
- SOTALOL HYDROCHLORIDE 80 MG AND 160MG TABLETS
- SECADREX
- WARFARIN
- SYSCOR MR
- METOPROLOL TARTRATE TABLETS BP 100MG
- RYTHMODAN
- VERAPAMIL (HYPERTENSION)
- NITROMIN
- REFACTO AF POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
- AMIL-CO
- ALPHAPARIN
- DYAZIDE
- VASOXINE
- TRITACE TABLET TITRATION PACK
- PLETAL TABLETS
- TENBEN
- CO-AMILOFRUSE 20/2.5MG TABLETS
- NIFEDIPINE
- INSPRA 25MG & 50 MG FILM-COATED TABLETS
- CATAPRES AMPOULES
- CYKLOKAPRON INJECTION
- TAMBOCOR INJECTION
- FERROUS SULPHATE TABLETS BP 200MG
- LEUCOMAX
- INTEGRILIN
- INDERETIC
- MYOVIEW
- TANATRIL
- EUCARDIC 6.25MG TABLETS
- DIXARIT (MENOPAUSAL DISORDERS)
- BENEFIX 250 IU / 500 IU / 1 000 IU / 2 000 IU
- VASCACE TABLETS
- SECTRAL 100MG AND 200MG
- NOVOSEVEN
- TRANDATE INJECTION
- UNIVER 180MG PROLONGED RELEASE CAPSULES
- RYTHMODAN RETARD
- ISOTARD XL
- OMACOR
- DEBRISOQUINE
- NATRILIX
- MODALIM
- COVERSYL (HYPERTENSION)
- DILTIAZEM HYDROCHLORIDE TABLETS 60MG
- OMNIPAQUE
- ANGIOPINE
- ORGARAN
- APRESOLINE TABLETS 25 MG
- MONIT
- IKOREL
- LESCOL (FLUVASTATIN* SODIUM) 20 MG AND 40 MG CAPSULES
- CO-AMILOZIDE (AMILORIDE, HYDROCHLOROTHIAZIDE)
- ACEBUTOLOL 100MG CAPSULES
- ODRIK
- ISTIN
- FORTIPINE LA 40MG MODIFIED-RELEASE TABLETS
- FELOTENS XL TABLETS
- ADALAT LA 30 MG PROLONGED-RELEASE TABLETS
- FIBROGAMMIN P
- GOPTEN
- CENTYL K
- TILDIEM 60MG MODIFIED-RELEASE TABLETS
- VISKALDIX TABLETS
- NITRONAL
- ADIZEM-SR CAPSULES
- PHENYLEPHRINE INJECTION 1%
- TENORET 50
- ANGIOPINE MR
- GEMFIBROZIL
- LABETALOL HYDROCHLORIDE (HYPERTENSION)
- HALF INDERAL
- NITRO-DUR
- DIOVAN 40MG FILM-COATED TABLETS
- LEXPEC
- PARMID XL 5 MG PROLONGED RELEASE TABLETS
- BEDRANOL 80MG SR CAPSULES
- HYGROTON
- LIPITOR 10MG, 20MG, 40MG, 80MG TABLETS
- APROTININ
- TAMBOCOR TABLETS
- ANGIOPINE LA
- ASPIRIN 75 MG GASTRO-RESISTANT TABLETS
- ZANIDIP 10 MG TABLETS
- CHOLESTAGEL FILM-COATED TABLETS
- ADIZEM-XL
- OLMETEC PLUS FILM-COATED TABLETS
- AMLODIPINE 5MG TABLETS
- ENALAPRIL MALEATE/HYDROCHLOROTHIAZIDE 20/12.5MG TABLETS
- RASILEZ TABLETS
- CO-AMILOFRUSE 40/5MG TABLETS
- CORGARETIC 40
- PROCORALAN
- KONAKION
- PHARMADREAMS - ENALAPRIL 10MG TABLETS
- GLYPRESSIN INJECTION
- APRINOX
- TICLID
- ALDOMET TABLETS 250 MG
- FLECAINIDE
- METHYLDOPA
- STARIL (CARDIAC FAILURE)
- ATENOLOL 100MG
- KALSPARE
Advert for Healthcare Professionals only