Bardoxolone (Reata/Abbott) Phase III trial terminated for Chronic Kidney Disease - 20-Oct-2012
Reata Pharma, in consultation with the BEACON Steering Committee, has decided to terminate the Phase III BEACON trial of bardoxolone methyl in patients with stage 4 Chronic Kidney Disease and Type 2 Diabetes. This decision was made based upon a recommendation of the Independent Data Monitoring Committee (IDMC) to stop the trial "for safety concerns due to excess serious adverse events and mortality in the bardoxolone methyl arm". Abbott Labs have the ex US rights.
Related News
Bardoxolone (Reata/Abbott) Phase III trial terminated for Chronic Kidney Disease
Januvia approved in UK for use in renally impaired diabetic patients
FreeStyle InsuLinx Blood Glucose Monitoring System (Abbott) is recalled in the USA
Genous stent (Orbus Neich) has lower restenosis rate than bare metal stents in ACS treatment
Inotuzumab ozogamicin (Pfizer) fails Phase III trial for NHL
European Commission approves HyQvia for treatment of primary and secondary Immunodeficiencies
Xience Xpedition 48 everolimus eluting coronary stent from Abbott Vascular has CE Mark
Biogen files Plegridy at FDA for treatment of relapsing Multiple Sclerosis
Related Diabetes and Endocrinology Information
Diabetes and Endocrinology Clinical Guidelines
Diabetes in pregnancy - Management of diabetes and its complications from pre-conception to the postnatal period
NICEType 1 diabetes
NICEDiabetes and Endocrinology Clinical Trials
Pancreatic Carcinoma: Chemoradiation Compared With Chemotherapy Alone After Induction Chemotherapy (CONKO-007)
Clinicaltrials.gov 04 April 2013A Multicenter Phase II Pilot Open Label (BKM120)
Clinicaltrials.gov 04 April 2013Diabetes and Endocrinology Medical Journal Abstracts
Exogenous insulin requirements do not differ between youth and adults with cystic fibrosis related diabetes
Pediatric Diabetes 28 January 2013Evaluation of glycated hemoglobin and fetal hemoglobin-adjusted HbA1c measurements in infants
Pediatric Diabetes 28 January 2013Diabetes and Endocrinology Medical Apps
Living medical textbook - Diabetes
Free
Diabetes Reference
£1.23
Related Diabetes and Endocrinology Drugs
- CERAZETTE
- MICROGYNON 30 ED
- CALCORT
- SOLU-CORTEF
- HUMAN VELOSULIN
- METRODIN HIGH PURITY
- SAIZEN
- GLUCOBAY
- TESTOGEL 50 MG GEL
- DIANETTE
- AREDIA
- RESTANDOL
- FEMULEN
- AVANDIA
- GLUCAGEN
- STRONAZON 400 MICROGRAMS MR CAPSULES
- DIDRONEL 200MG TABLETS
- TRIADENE
- PARLODEL 1 MG TABLETS
- SKELID
- VIRIDAL DUO
- NORIDAY
- NORGESTON
- LORON 520
- MARVELON
- MENOGON
- THYROGEN 0.9 MG POWDER FOR SOLUTION FOR INJECTION
- LEVOTHYROXINE 25MCG TABLETS
- APIDRA 100 U/ML, SOLUTION FOR INJECTION
- PRO-VIRON
- TRINORDIOL
- NORDITROPIN
- HAEMACCEL
- GLICLAZIDE
- NEOGEST
- VICTOZA 6 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED PEN
- STARLIX FILM-COATED TABLETS
- DEXSOL
- CERELLE 75 MICROGRAMS FILM-COATED TABLETS
- NOVONORM
- SCHERING PC4
- OVYSMEN
- MIRENA (CONTRACEPTION)
- HUMALOG MIX25 100U/ML SUSPENSION FOR INJECTION IN VIAL/CARTRIDGE/KWIKPEN SUSPENSION FOR INJECTION. MIX50 100U/ML SUSPENSION FOR INJECTION IN CARTRIDGE/KWIKPEN
- BINOVUM ORAL CONTRACEPTIVE TABLETS
- ZOMETA 4MG/5ML CONCENTRATE FOR SOLUTION FOR INFUSION
- ANDROCUR
- MICROGYNON 30
- ZOMACTON
- INSUMAN RAPID (100 IU/ML)
- FEMODETTE
- HUMATROPE 6MG, 12MG, OR 24MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION
- ELTROXIN 100MICROGRAMS PER 5ML ORAL SOLUTION
- AMARYL TABLETS
- CAP, CONTRACEPTIVE
- BONEFOS TABLETS
- EUGYNON 30
- ZEMPLAR SOFT CAPSULES 2 MCG
- INSUMAN BASAL (100 IU/ML)
- ACTRAPID 100 IU/ML, SOLUTION FOR INJECTION IN A VIAL
- CILEST
- MINULET
- LEVITRA
- DDAVP TABLETS 0.1MG
- NORISTERAT
- NOVORAPID 100 U/ML IN A VIAL, NOVORAPID PENFILL 100 U/ML, NOVORAPID FLEXPEN 100 U/ML, NOVORAPID FLEXTOUCH 100 U/ML
- LOGYNON ED
- GLUCOPHAGE
- MEDRONE TABLETS 2MG, 4MG
- NEO MERCAZOLE
- EUCREAS FILM-COATED TABLETS
- ELTROXIN 100MCG TABLETS
- HUMALOG 100U/ML, SOLUTION FOR INJECTION IN VIAL, HUMALOG 100U/ML, SOLUTION FOR INJECTION IN CARTRIDGE, HUMALOG KWIKPEN 100U/ML, SOLUTION FOR INJECTION
- HUMULIN I (ISOPHANE) 100IU/ML SUSPENSION FOR INJECTION IN VIAL / CARTRIDGE
- HYDROCORTONE
- GALVUS 50 MG TABLETS
- METFORMIN 500MG AND 850MG FILM-COATED TABLETS
- BREVINOR
- VIAGRA
- COMPETACT FILM-COATED TABLETS
- SYNPHASE
- NUVARING
- CHLORPROPAMIDE
- PORK MIXTARD 30
- NEBIDO 1000 MG/4ML
- TRI-MINULET
- PREOTACT SOLUTION FOR INJECTION
- ADIURETIN NASAL SPRAY
- FEMODENE
- NORIMIN
- HYPURIN BOVINE ISOPHANE CARTRIDGES
- VITILE XL 30 MG PROLONGED-RELEASE TABLETS
- TRINOVUM
- HYPURIN BOVINE PROTAMINE ZINC
- ELTROXIN 50MCG TABLETS
- GLURENORM
- ORTHO DIAPHRAGMS
- PRANDIN 0.5MG, 1MG, 2MG TABLETS
- HUMULIN M1 - M5
- SANDOSTATIN LAR
- DEPO-MEDRONE
- JANUVIA 25MG, 50MG, 100MG FILM-COATED TABLETS
- HYPURIN BOVINE LENTE
- OVRANETTE 150/30 MICROGRAMS COATED TABLETS
- JANUMET 50 MG/1000 MG FILM-COATED TABLETS
- CIALIS 2.5MG, 5MG, 10MG & 20MG FILM-COATED TABLETS
- INSUMAN COMB
- SOMATULINE LA
- NORINYL-1
- INSULATARD 100 IU/ML, INSULATARD PENFILL 100 IU/ML, INSULATARD INNOLET 100 IU/ML
- SOMAVERT SOLUTION FOR INJECTION
- HYPURIN BOVINE ISOPHANE VIALS
- HUMULIN S (SOLUBLE) 100IU/ML SOLUTION FOR INJECTION IN VIAL / CARTRIDGE
- NOVA-T
- LEDERSPAN 20 MG
- HYDROCORTISTAB
- DDAVP/DESMOPRESSIN INTRANASAL SOLUTION
- TOLBUTAMIDE TABLETS BP 500MG
- LEVEMIR
- LENTARD MC
- ORTHO-CREME
- ELLAONE 30 MG TABLET
- FORCALTONIN 100
- LEVONELLE
- FEMODENE ED
- DEXAMETHASONE 3.3 MG/ML SOLUTION FOR INJECTION
- GONAL-F 1050 IU/1.75 ML (77MCG/1.75 ML)
- GENOTROPIN
- TESTODERM
- DDAVP/DESMOPRESSIN INJECTION
- DELTACORTRIL
- INTRINSA
- GHRH FERRING
- HUMULIN LENTE
- MERCILON
- EFCORTESOL
- MINODIAB
- NOVOMIX 30 PENFILL 100 U/ML, NOVOMIX 30 FLEXPEN 100 U/ML
- NEXPLANON 68 MG IMPLANT FOR SUBDERMAL USE
- SOLU-MEDRONE
- PROPYLTHIOURACIL
- ORTHO-FORMS
- BYETTA 5 , 10 MICROGRAMS SOLUTION FOR INJECTION, PREFILLED PEN
- FLUDARABINE PHOSPHATE 50 MG POWDER FOR SOLUTION FOR INJECTION OR INFUSION
- MUSE
- PRECORTISYL FORTE
- MICRONOR
- HYPURIN PORCINE 30/70 MIX CARTRIDGES
- LOGYNON
- SUSTANON 100
- OMNIC MR
- PRENTIF
- DDAVP MELT 60MCG, 120MCG AND 240MCG ORAL LYOPHILISATE
- MULTILOAD CU 250
- DECAPEPTYL SR 11.25MG
- GLIBENCLAMIDE 2.5MG TABLETS
- MIACALCIC 50 IU/ML
- DEPO-PROVERA INJECTION
- PREGNYL 5000IU
- EXUBERA
- ONGLYZA 2.5MG & 5MG FILM-COATED TABLETS
- MICROVAL
- DUMAS
- ACTOS TABLETS
- DAONIL
- SANDOSTATIN 0.05MG/ML, 0.1 MG/ML, 0.5 MG/ML AMPOULES AND MULTIDOSE VIAL 1 MG/5 ML
- KENALOG
- DIAMICRON
- DECAPEPTYL SR 3MG
- LYXUMIA 10 MICROGRAMS SOLUTION FOR INJECTION
- NORDITROPIN SIMPLEXX
- FLORINEF
- GLUCOSE INTRAVENOUS
- LOESTRIN 20/30
- GLIBENESE
Advert for Healthcare Professionals only