CHMP refuses recommendation of Istodax( Celgene) for T-cell Lymphoma - 22-Jul-2012
On 19 July 2012, the Committee for Medicinal Products for Human Use (CHMP) adopted a positive opinion, recommending the granting of a conditional marketing authorisation for the medicinal product Xalkori (crizotinib), 200 mg, 250 mg, hard capsule from Pfizer and intended for the treatment of adults with previously treated anaplastic lymphoma kinase (ALK)-positive advanced Non-Small Cell Lung Cancer (NSCLC) . The benefits with Xalkori are its important activity on ALK-positive NSCLC with an objective response rate of 60% (95% CI, 51% - 69%) and a median progression free survival (PFS) of 9.2 months (95% CI, 7.3 months – 12.7 months).
Related News
Belinostat (TopoTarget/Spectrum) success in BELIEF study for PTCL
CHMP refuses recommendation of Istodax( Celgene) for T-cell Lymphoma
Minophagen extends marketing rights to bexarotene for T-Cell Lymphoma
CHMP rejects Folotyn (AllosTherapeutics and Mundipharma) for T-Cell Lymphoma
Mechlorethamine hydrochloride gel is filed at FDA for Mycosis Fungoides
Fasiglifam (Takeda) success in Phase III trial for treatment of Type 2 Diabetes
NICE recommends Betmiga (Astellas) for patients with Overactive Bladder
Three Phase III studies of Brintellix (Lundbeck/Takeda) for Depression meet primary endpoint
Related Oncology Information
Oncology Clinical Guidelines
Familial breast cancer: The classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care
NICEProstate cancer: diagnosis and treatment
NICEOncology Clinical Trials
Multi-Center Randomized Clinical Trial Irreversible Electroporation for the Ablation of Localized Prostate Cancer
Clinicaltrials.gov 08 April 2013Pancreatic Carcinoma: Chemoradiation Compared With Chemotherapy Alone After Induction Chemotherapy (CONKO-007)
Clinicaltrials.gov 04 April 2013Oncology Medical Journal Abstracts
Bone mass density, fracture history, self-reported osteoporosis as proxy variables for estrogen and the risk of non-small-cell lung cancer—A population based cohort study, the HUNT study: Are proxy variables friends or faults?
Lung Cancer 24 April 2013Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: A systematic review with meta-analysis
Lung Cancer 22 April 2013Oncology Medical Apps
CCO Oncology inPractice
Free
Cancer Signs and Symptoms
Free
Related Oncology Drugs
- FLUDARA ORAL 10 MG FILM-COATED TABLET
- FASLODEX 250 MG SOLUTION FOR INJECTION
- IRESSA 250MG FILM-COATED TABLETS
- HYDREA 500 MG HARD CAPSULES
- NEXAVAR 200MG FILM-COATED TABLETS
- TOMUDEX
- CYPROSTAT 100MG
- NIPENT 10 MG POWDER FOR SOLUTION FOR INJECTION, POWDER FOR SOLUTION FOR INFUSION
- PROCARBAZINE CAPSULES 50MG
- EFUDIX CREAM
- BICALUTAMIDE 50MG FILM-COATED TABLETS
- TAXOTERE 20MG/1ML CONCENTRATE FOR SOLUTION FOR INFUSION
- MAXTREX TABLETS 10 MG
- SUTENT 12.5MG, 25MG, 37.5MG AND 50MG HARD CAPSULES
- TAMOFEN (CARCINOMA)
- CYCLOPHOSPHAMIDE 50 TABLETS
- DOXORUBICIN 2MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- ATRIANCE 5 MG/ML SOLUTION FOR INFUSION
- NOVGOS
- MITOMYCIN C
- VINBLASTINE SULPHATE 1 MG/ML INJECTION
- YONDELIS SOLUTION FOR INFUSION.
- CAMPTO 20MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- MYOCET
- ERBITUX 5MG/ML SOLUTION FOR INFUSION
- FEMARA
- HERCEPTIN 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION
- CARDIOXANE 500MG POWDER FOR SOLUTION FOR INFUSION
- ZAVEDOS
- CARBOPLATIN 10MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- GEMZAR 200MG POWDER FOR SOLUTION FOR INFUSION, GEMZAR 1000MG POWDER FOR SOLUTION FOR INFUSION
- AROMASIN
- HYCAMTIN 0.25MG AND 1 MG HARD CAPSULE
- XELODA 150MG AND 500MG FILM-COATED TABLETS
- MABTHERA 100MG AND 500MG CONCENTRATE FOR SOLUTION FOR INFUSION
- XALUPRINE
- SOLTAMOX
- BICALUTAMIDE 150MG FILM-COATED TABLETS
- JEVTANA
- FARESTON
- NAVELBINE 10 MG / ML CONCENTRATE FOR SOLUTION FOR INFUSION
- LEUKERAN TABLETS 2 MG
- ROFERON-A PRE-FILLED SYRINGE
- ARIMIDEX 1MG FILM-COATED TABLET
- PARAPLATIN
- PROLEUKIN
- VESANOID 10MG SOFT CAPSULES
- LEVOFOLINIC ACID 50 MG/ML SOLUTION FOR INJECTION OR INFUSION
- GEMCITABINE 200 MG POWDER FOR SOLUTION FOR INFUSION / GEMCITABINE 1 G POWDER FOR SOLUTION FOR INFUSION / GEMCITABINE 2 G POWDER FOR SOLUTION FOR INFUSION
- TEMODAL CAPSULES
- REVLIMID
- FIRMAGON 120MG INJECTION
- MAXTREX TABLETS 2.5 MG
- TAXOL
- HALAVEN 0.44 MG/ML SOLUTION FOR INJECTION
- ONCOTICE
- ETOPOPHOS 100MG POWDER FOR SOLUTION FOR INJECTION
- VOTRIENT 200 MG FILM-COATED TABLETS
- MEGACE 160 MG TABLETS
- FLUOROURACIL 25 MG/ML INJECTION
- TARCEVA 25MG, 100MG AND 150MG FILM-COATED TABLETS
- TOPOTECAN 4 MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION
- PERJETA 420 MG CONCENTRATE FOR SOLUTION FOR INFUSION
- DACARBAZINE 100MG, 200MG, 500MG, 1000MG
- ROFERON-A 18MIU/0.6ML CARTRIDGE
- MITOXANTRONE (MITOZANTRONE) 2 MG/ML STERILE CONCENTRATE
- DAUNOXOME INJECTION (LIPOSOMAL DAUNORUBICIN)
- XAGRID 0.5MG HARD CAPSULE
- PROSTAP 3 DCS
- TEPADINA 100 MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION
- KYTRIL TABLETS 1MG AND 2MG
- NASTROSA 1MG FILM-COATED TABLETS
- CYTARABINE INJECTION SOLUTION 20MG/ML AND 100MG/ML
- CASODEX 150 MG FILM-COATED TABLETS.
- VEPESID SOFT CAPSULES 50 MG AND 100 MG
- CAELYX 2MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- LEUSTAT INJECTION
- VOTRIENT 200 MG FILM-COATED TABLETS
- ZALTRAP 25MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- ISOVORIN
- TASIGNA 200 MG HARD CAPSULES
- SPRYCEL 20MG, 50MG, 80MG, 100MG AND 140MG FILM COATED TABLETS
- EVOLTRA 1MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- PROSTAP SR
- PHARMORUBICIN
- ELOXATIN 5 MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- VOTRIENT 200 MG AND 400 MG FILM COATED TABLETS
- GLIVEC
- PHOTOFRIN
- GLIADEL 7.7MG IMPLANT
- TESTOSTERONE ENANTATE AMPOULES
- VINCRISTINE SULPHATE 1 MG/ML INJECTION
- ZOLADEX
- VELCADE 3.5 MG POWDER FOR SOLUTION FOR INJECTION.
- PROSTAP SR DCS
- FIRMAGON 80MG INJECTION
- ESTRACYT CAPSULES
- HYCAMTIN 1MG AND 4MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION
- ONKOTRONE INJECTION
- TYVERB
- AVASTIN 25MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- ERWINASE
- GRANISETRON
- PROVERA TABLETS 100 MG
- CASODEX 50 MG FILM-COATED TABLETS
- UFTORAL HARD CAPSULES
- TAXOTERE 160MG/8ML CONCENTRATE FOR SOLUTION FOR INFUSION
- TAXCEUS 20MG/ML CONCENTRATE FOR SOLUTION FOR INFUSION
- UTOVLAN
- PROSTAP 3 LEUPRORELIN ACETATE DEPOT INJECTION 11.25MG
- TAXOTERE 80MG/4ML CONCENTRATE FOR SOLUTION FOR INFUSION
- CYPROSTAT 50MG
Advert for Healthcare Professionals only