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Research has offered up six further genetic variants involved in type 2 diabetes, with one of these new variants also appearing to be implicated as a cause of prostate cancer.
The findings bring the total number of genetic risk factors associated with type 2 diabetes up to 16.
An international multi-group collaboration of 40 centres in Europe and North America assessed combined genetic data from more than 70,000 people.
Genetic variant JAZF1 was found to contain a separate variant linked to prostate cancer and is the second gene that appears to play a role in both conditions.
The findings may have important implications for the future design of drugs for both prostate cancer and diabetes.
Senior author Mark McCarthy from the University of Oxford explained that none of the genes found was previously "on the radar screen" of diabetes researchers.
"Each of these genes, therefore, provides new clues to the processes that go wrong when diabetes develops, and each provides an opportunity for the generation of new approaches for treating or preventing this condition," he said.
Further research into genetic variant JAZF1 linked to type 2 diabetes and prostate cancer also needs to be untaken, researchers stressed.
The research is published in the advanced online edition of Nature Genetics.
Click here to learn more about diabetes
- Men with type-2 diabetes at greater risk of cardiovascular death 06/01/09
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- Leptin study could lead to new diabetes treatment 23/12/08
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- Anti-obesity drugs can treat type 2 diabetes, expert claims 17/12/08
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PRANDIN Tablets - 49.44%
... in patients with Type 2 diabetes (Non Insulin-Dependent Diabetes Mellitus (NIDDM)) whose hyperglycaemia can no longer be controlled satisfactorily by diet, weight reduction and exercise. Repaglinide is also indicated in combination with metformin in Type 2 diabetes patients who are not ... -
DDAVP - 49.42%
... and treatment of vasopressin-sensitive cranial diabetes insipidus; establishing renal concentration capacity. DDAVP Tablets: Treatment of vasopressin-sensitive cranial diabetes insipidus; treatment of post-hypophysectomy polyuria/ polydipsia. DDAVP/Desmopressin Injection: Cranial diabetes insipidus ... -
JANUVIA Film-Coated Tablets - 47.95%
JANUVIA is indicated in patients with type 2 diabetes mellitus to improve glycaemic control in combination with metformin when diet and exercise, plus metformin do not provide adequate glycaemic control. For patients with type 2 diabetes mellitus in whom use of a PPAR? agonist (i.e. a ... -
EXUBERA - 47.95%
... for the treatment of adult patients with type 2 diabetes mellitus not adequately controlled with oral antidiabetic agents and requiring insulin therapy. EXUBERA is also indicated for the treatment of adult patients with type 1 diabetes mellitus, in addition to long or intermediate acting ... -
NOCUTIL - 47.95%
Treatment of idiopathic central diabetes insipidus, or diabetes insipidus occurring after hypophysectomy, cranial trauma, or surgery in the pituitary region ... -
GLUCOPHAGE - 47.95%
Non-insulin dependent (type II) diabetes either alone or with sulphonylureas. Adjuvant therapy in insulin-dependent diabetes, particularly in the obese ...

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