Neonatal/Perinatal Medicine Topic Homepage

Medical Videos

An Introduction to Diagnosing Gastroschisis or Omphalocele
An Introduction to Diagnosing Gastroschisis or Omphalocele
An Introduction to Twin-Twin Transfusion Syndrome and Possible Treatments
An Introduction to Twin-Twin Transfusion Syndrome and Possible Treatments

Clinical Guidelines

Antibiotics for early-onset neonatal infection: Antibiotics for the prevention and treatment of early-onset neonatal infection

Aug 2012

Early-onset neonatal bacterial infection (infection with onset within 72 hours of birth) is a..

... significant cause of mortality and morbidity in newborn babies. Parent organisations and the scientific literature report that there can be unnecessary delays in recognising and treating sick babies. In addition, concern about the possibility of early-onset neonatal infection is common. This concern is an important influence on the care given to pregnant women and newborn babies. There is wide variation in how the risk of early-onset neonatal infection is managed in healthy babies.

Recognition and treatment of neonatal jaundice

May 2010

This guideline provides guidance regarding the recognition, assessment and treatment of neonatal..

... jaundice. The advice is based on evidence where this is available and on consensus-based practice where it is not.

Online CME

Maternal Obesity: How Big an Impact Does It Have on Offspring Prenatally and During Postnatal Life?

Sep 2013
... gynecologists, endocrinologists, and other physicians who care for obese women. The goal of this activity is to evaluate the link between maternal obesity and obesity among offspring. Upon completion of this activity, participants will be able to: Evaluate the epidemiology and risks for offspring of maternal obesity, Analyze the effect of maternal obesity on the placenta and fetal organs, Distinguish the preferred means to treat obesity during pregnancy, Assess the effects of maternal obesity on the metabolism of the infant after delivery.

When an Aging Colleague Seems Impaired

Nov 2013
... effectively to suspected cognitive impairment among physicians.

Clinical Trials

Safety and Efficacy of Propranolol Eye Drops in Treating Retinopathy of Premature (DROP-PROP)


The aim of the present study is to evaluate the safety and efficacy of propranolol eye drops in preterm newborns with a precocious stage of retinopathy of prematurity (ROP). Preterm newborns (gestational age 23-32 weeks) with a stage 2 ROP (zone II without plus) will receive propranolol eye drops treatment until..

... retinal vascularization will be completed. Propranolol concentrations will be measured on dried blood spots during the first 3 days of treatment and at the steady state. Cardiovascular and respiratory parameters will be continuously monitored. Blood samplings checking metabolic, renal and liver functions will be performed periodically, as well as cardiac function, in order to verify the treatment safety. Serial ophthalmological evaluations will be planned to monitor the efficacy of the treatment, the ROP progression and the possible complications.

Prevention of Hepatitis B Virus Mother-to-child Transmission by Serovaccination.


The prevalence of HBsAg carriage in pregnant women varies in France, according to the native country, with highest rates in those originating from sub-Saharan Africa and Asia (5 to 8 % in Parisian area). The level of HBV-DNA varies according to HBe status and geographical origin, and is strongly predictive of the risk..

... of HBV mother-to-child transmission (MTCT). It has been shown that the rate of vertical transmission (Chinese study by Yuan J et al) was 0 % in newborns to mothers whom HBV-DNA was < 105 copies/mL and up to more than 40 % in newborns to mothers with high viral loads > 108 copies/mL, despite HBIg and vaccine at birth. Thus, data are needed concerning the current practices about the prevention of HBV MTCT in France, and their results.
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