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Drug Details

Lemsip Max All In One Liquid

• Drug Class Description
  Paracetamol has analgesic and antipyretic actions. Phenylephrine hydrochloride is a sympathomimetic agent. Guaifenesin is an expectorant. Cetylpyridinium Chloride is a cationic disinfectant.
• Generic Name
  paracetamol, phenylephrine hydrochloride, guaifenesin, cetylpyridinium chloride
• Presentation
  Oral Solution
• Description
  Each 20ml dose contains: Paracetamol 1000mg Phenylephrine Hydrochloride 12.18mg Guaifenesin 200mg Cetylpyridinium Chloride 3.0mg Each 20ml dose also contains potassium 23mg, sodium 19mg, propylene glycol 4300mg, sorbitol 3000mg, maltitol liquid 2000mg and ethanol 3000mg
• Indications
  

  For the short term symptomatic relief of the symptoms of colds and influenza, including aches and pains, headache, nasal congestion, tickly sore throat and chesty coughs.

• Adult Dosage
  

  Adults and children 12 years and over: One 20ml dose (four 5ml spoonfuls) up to 4 times a day as required.

  The dose must not be repeated more frequently than every four hours.

  Maximum of 4 doses in any 24 hours.

• Child Dosage
  

  Not recommended for children under 12 years of age.

• Contra Indications
  

  Patients with known hypersensitivity to paracetamol, phenylephrine hydrochloride, guaifenesin or cetylpyridinium chloride or any of the other ingredients.

  Contra-indicated during pregnancy.

• Special Precautions
  

  his product is not suitable for long term use.

  Paracetamol should be used with care in patients with severe renal or hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.

  Do not take with other cold or decongestant medicines or any other paracetamol-containing products.

  Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.

  Phenylephrine should be used with care in patients with hyperthyroidism, cardiovascular disease, diabetes mellitus, closed angle glaucoma, prostatic enlargement and hypertension.

  Do not exceed the stated dose.

  If symptoms persist consult your doctor.

  Each 20ml dose contains 2g Liquid Maltitol and approximately 3g of Sorbitol. Patients with rare hereditary problems of fructose intolerance should not take this medicine. This product may have a mild laxative effect.

  This product contains 19% (v/v) ethanol. Each 20ml dose contains up to 3g of ethanol (alcohol) equivalent to 32ml of wine or 76ml of beer. Harmful for those suffering from alcoholism. To be taken into account in pregnant or breast feeding women, children and high-risk groups such as patients with liver disease, epilepsy. The amount of alcohol in this medicinal product may alter the effects of other medicines. The amount of alcohol in this medicinal product may impair the ability to drive or use machines.

  This product contains propylene glycol, which may cause alcohol-like symptoms.

• Interactions
  

  The speed of absorption of paracetamol may be increased by metoclopramide or domperidone; and absorption reduced by colestyramine. The anti-coagulant effect of warfarin and other coumarins may be enhanced by prolonged regular use of paracetamol with increased risk of bleeding; occasional doses have no significant effect. Alcohol may potentiate the hepatotoxicity of paracetamol.

  Phenylephrine may reduce the efficacy of beta-blocking drugs and antihypertensive drugs; the product is contra-indicated in such circumstances.

  With phenylephrine there is a possibility that an increased risk of arrhythmias may occur in patients receiving cardiac glycosides or tri-cyclic anti-depressants. Phenylephrine interacts with monoamine oxidase inhibitors; it should not therefore, be taken by patients receiving monoamine oxidase inhibitors or within 14 days of stopping such medication.

  Guaifenesin may interfere with diagnostic measurements of urinary 5-hydroxyindoleacetic acid or vanillylmandelic acid.

   

• Adverse Drug Reactions
  

  Undesirable effects with paracetamol are rare, however, hypersensitivity including skin rashes may occur. There have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis after regular or excessive ingestion of paracetamol, and of acute pancreatitis after ingestion of above normal dosage.

  Undesirable effects are rare with normal doses of phenylephrine, however it can cause the adverse effects typical of sympathomimetics including: hypertension, palpitations (tachycardia), headache, dizziness, vomiting, diarrhoea and insomnia.

  Guaifenesin has occasionally been reported to cause gastrointestinal discomfort.