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Drug Details

Lemsip Max Daytime Cold & Flu Relief

• Presentation
  Red/yellow hard gelatine capsules.
• Description
  Lemsip Max Daytime Cold & Flu Relief.
• Indications
  

  For the relief of symptoms associated with the common cold and influenza, including relief of aches and pains, sore throat, headache, fatigue and drowsiness, nasal congestion and lowering of temperature.

• Adult Dosage
  

  Adults and children 12 years and over:

  Two capsules every 4-6 hours to a maximum of 4 doses in any 24 hour period or up to a maximum of 3 doses in any 24 hours period if a night-time paracetamol-containing product is taken at bedtime.

  Do not exceed 8 capsules in any 24 hours.

  Particularly appropriate for daytime use.

  Swallow whole with water. Do not chew.

  Do not give to children under 12 years.

• Contra Indications
  

  Paracetamol: Hypersensitivity to paracetamol or any of the other constituents.

  Caffeine: Should be given with care to patients with a history of peptic ulcer.

  Phenylephrine hydrochloride: Severe coronary heart disease and cardiovascular disorders. Hypertension. Hyperthyroidism. Contraindicated in patients currently receiving or within two weeks of stopping therapy with monoamine oxidase inhibitors.

• Special Precautions
  

  Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.

  Use with caution in patients with Raynaud's Phenomenon and diabetes mellitus.

  Label: Immediate medical advice should be sought in the event of an overdose, even if you feel well.

  Leaflet: Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.

  Do not exceed the stated dose. Do not take with any other paracetamol-containing products. If symptoms persist consult your doctor. Keep out of the reach of children. If you are pregnant or are being prescribed medicine by your doctor, seek his advice before taking this product. Contains paracetamol (panel).

• Interactions
  

  The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by cholestyramine.

  The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

  Phenylephrine may adversely interact with other sympathomimetics, vasodilators and beta-blockers. Drugs which induce hepatic microsomal enzymes, such as alcohol, barbiturates, monoamine oxidase inhibitors and tricyclic antidepressants, may increase the hepatotoxicity of paracetamol, particularly after overdosage. Contraindicated in patients currently receiving or within two weeks of stopping therapy with monoamine oxidase inhibitors because of a risk of hypertensive crisis.

• Adverse Drug Reactions
  

  Adverse effects of paracetamol are rare, but hypersensitivity including skin rash may occur. There have been a few reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causally related to paracetamol.

  Phenylephrine hydrochloride: High blood pressure with headache, vomiting and rarely, palpitations. Also rare reports of allergic reactions.

  Caffeine, if taken close to bedtime, may interfere with sleep.