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Drug Details

Ascorbic Acid Tablets BP 500mg

• Presentation
  White uncoated tablets. White, circular, flat bevelled-edge uncoated tablets impressed “C” and the identifying letters “AN” on one face; or, as an alternative, plain tablets devoid of surface markings.
• Description
  Each tablet contains 500mg ascorbic acid
• Indications
  

  1) Ascorbic acid is a synthetic vitamin C and is specific in the treatment of scurvy.

• Adult Dosage
  

  Tablets should be chewed before swallowing.

  Adults including elderly: 500mg-1g two or three times daily.

  Children over 12 years: 500mg two or three times daily.

  Children 6-12 years: 500mg twice a day.

  For oral administration.

• Contra Indications
  

  Hyperoxaluria.

• Special Precautions
  

  Increased intake of ascorbic acid over a prolonged period may result in an increase in renal clearance and deficiency may result if it is withdrawn too rapidly.

• Interactions
  

  Concomitant administration of aluminium-containing antacids may increase urinary aluminium elimination. Concurrent administration of antacids and ascorbic acid is not recommended, especially in patients with renal insufficiency.

  Concomitant administration of aspirin and ascorbic acid may interfere with absorption of ascorbic acid. Renal excretion of salicylate is not affected and does not lead to reduced anti-inflammatory effects of aspirin.

  Concurrent administration of ascorbic acid with desferrioxamine enhances urinary iron excretion. Cases of cardiomyopathy and congestive heart failure have been reported in patients with idiopathic haemochromatosis and thalassaemias receiving desferrioxamine who were subsequently given ascorbic acid. Ascorbic acid should be used with caution in these patients and cardiac function monitored.

  Ascorbic acid may interfere with biochemical determinations of creatinine, uric acid and glucose in samples of blood and urine.

• Adverse Drug Reactions
  

  Nausea, vomiting and stomach cramps.

  Flushing or redness of skin, headache, mild increase in urination with doses greater than 600mg per day.

  Large doses of ascorbic acid (greater than 1g per day) may cause diarrhoea.