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Drug Details

Panadol OA 1000 mg Tablets

• Presentation
  Film-coated tablet. White, capsule-shaped tablets having flat edges, debossed with 'PAN 1G' on one side with a break-line on both sides. The score line is only to facilitate breaking for ease of swallowing and not to divide into equal doses.
• Description
  Each tablet contains paracetamol 1000 mg
• Indications
  For the management of mild to moderate pain, including osteoarthritis and for pyrexia.
• Adult Dosage
  

  Panadol OA 1000 mg Tablets are for oral administration.

  Adults (including the elderly):

  One tablet up to 4 times daily as required.

  Not to be given to children under 12 years.

  The minimum dosing interval is 4 hours and the maximum daily dose is 4000 mg (4 tablets).

• Contra Indications
  

  Hypersensitivity to paracetamol or any of the other constituents.

• Special Precautions
  

  Care is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.

  Do not exceed the stated dose.

  Patients should be advised not to take other paracetamol-containing products concurrently.

  This product should only be used by the person for whom it is prescribed when clearly necessary.

   

  Pack label:

  Immediate medical advice should be sought in the event of an overdose, even if you feel well.

  Do not take with any other paracetamol-containing products.

   

  Patient Information Leaflet:

  Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.

• Interactions
  

  The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by colestyramine. The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding; occasional doses have no significant effect.

• Adverse Drug Reactions
  

  Adverse effects of paracetamol are rare but hypersensitivity including skin rash may occur.

  There have been very rare reports of blood dyscrasias including thrombocytopenia and agranulocytosis, but these were not necessarily causally related to paracetamol.