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Drug Details

PARAPLATIN

• Drug Class Description
  Alkylating cytotoxics.
• Generic Name
  Carboplatin
• Presentation
  Injection, carboplatin 10 mg /mL.
• Description
  Solution in vials.
• Indications
  

  Treatment of advanced ovarian carcinoma of epithelial origin in (a) first line therapy, (b) second line therapy after other treatments have failed. Treatment of small cell carcinoma of the lung.

• Child Dosage
  Insufficient usage in paediatrics to allow dosage recommendations to be made.
• Contra Indications
  

  Severe pre-existing renal impairment (creatinine clearance <20mL/minute). Severely myelosuppressed patients. History of several allergic reactions to Paraplatin or other platinum- containing compounds. Lactation.

• Special Precautions
  Should be administered by individuals experienced in the  individuals experienced in the use of antineoplastic therapy. See data sheet. Pregnancy.
• Interactions
  Nephrotoxic compounds.
• Adverse Drug Reactions
  Myelosuppression. Renal toxicity. Nausea and vomiting. See data sheet.