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Drug Details

GANDA

• Drug Class Description
  Adrenergic neurone blockers / sympathomimetics.
• Generic Name
  Guanethidine, adrenaline [epinephrine]
• Presentation
  '1 + 0.2': guanethidine monosulphate 1%, adrenaline 0.2%. '3 + 0.5': guanethidine monosulphate 3%, adrenaline 0.5%.
• Description
  Eye drops.
• Indications
  Glaucoma.
• Adult Dosage
  1 drop once or twice daily.
• Contra Indications
  Narrow angle glaucoma. Aphakia.
• Special Precautions
  Examine conjunctiva and cornea every 6 months during long term use; discontinue if damage is seen.
• Interactions
  MAOIs.
• Adverse Drug Reactions
  

  Eye discomfort, headache, hyperaemia, skin reactions, melanosis. Systemic effects (rare). Paradoxical rise in pressure, ptosis, superficial punctate keratitis.