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Drug Details

XYLOTOX 2 E80

• Drug Class Description
  Local anaesthetics.
• Generic Name
  Lidocaine [lignocaine], adrenaline (epinephrine)
• Presentation
  Solution for injection, lidocaine hydrochloride monohydrate 24.65mg equivalent to lidocaine base 20mg and adrenaline hydrogen tartrate 25.0 micrograms corresponding to adrenaline 12.5 micrograms.
• Description
  Solution for injection in cartridges for use in dental-type syringes.
• Indications
  Local anaesthetic solution with vasoconstrictor for dental infiltration anaesthesia where a vasoconstrictor is indicated.
• Contra Indications
  

  Known hypersensitivity to anaesthetics of the amide type. Not for intravenous use. Contraindicated for anaesthesia of the fingers, toes, tip of nose and penis.

• Special Precautions
  

  Epilepsy cardiac disease particularly with arrhythmia or hypertension, impaired respiratory function, thyrotoxicosis, hypovolaemia, acute porphyria and impaired hepatic function. Pregnancy and lactation. Avoid accidental intravascular injection.

• Interactions
  Tricyclic antidepressants.
• Adverse Drug Reactions
  

  Reactions primarily of two types, typified by stimulation and depression of the cerebral cortex and medulla, respectively. Slow onset - stimulation leading to nervousness, dizziness, blurred vision, nausea, tremor, convulsions and respiratory arrest. Rapid onset - depression leading primarily to respiratory arrest, cardiovascular collapse and cardiac arrest.