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Drug Details

HB-VAX II

• Drug Class Description
  Genetically derived surface antigens (vaccines).
• Generic Name
  Hepatitis B
• Presentation
  HB-Vax II: Hepatitis B surface antigen 10 microgram per mL adsorbed onto aluminium hydroxide. HB-Vax II 40: Hepatitis B surface antigen 40 microgram per mL adsorbed onto aluminium hydroxide. HB-Vax II Paediatric: Hepatitis B surface antigen 5 microgram per 0 .5 mL adsorbed onto aluminium hydroxide.
• Description
  HB-Vax II: suspension in pre- filled syringe or vial. HB-Vax II 40: suspension in vial. HB-Vax II Paediatric: suspension in pre-filled syringe.
• Indications
  

  HB-Vax II and HB-Vax II Paediatric: Active immunisation against hepatitis B virus. HB-Vax II 40: Active immunisation against hepatitis B virus in dialysis and predialysis dialysis and predialysis patients.

• Adult Dosage
  

  HB-Vax II: 1 L by intramuscular injection into the deltoid muscle, repeated 1 month and 6 months later.

  Rapid immunisation, 1 mL by intramuscular injection, repeated 1 month, 2 months and 12 months later. HB-Vax II 40: 1 mL by intramuscular injection into the deltoid muscle, repeated 1 month and 6 months later.

• Child Dosage
  HB-Vax II and HB-Vax II Paediatric: Under 16 years, 0.5 mL by intramuscular injection into the deltoid muscle, repeated 1 month and 6 months later. Rapid immunisation, 0 .5 mL by intramuscular injection, repeated 1 month, 2 months and 12 months later. HB-Vax II 40: 1 mL by intramuscular injection into the deltoid muscle, repeated 1 month and 6 months later.
• Contra Indications
  Severe febrile infections.
• Special Precautions
  Dialysed or immunocompromised patients may need further doses. Severe cardiac or respiratory dysfunction. Pregnancy, lactation.
• Adverse Drug Reactions
  Mild transient local soreness, erythema and induration at injection site, low grade fever, malaise, rash, nausea, dizziness.