Drug Class Description Toxoid vaccines plus inactivated surface antigens (vaccines).
Generic Name Haemophilus influenzae type b, diptheria, tetanus, pertussis
Presentation Triple antigen adsorbed on aluminium hydroxide, containing diphtheria toxoid not less than 30 i.u., tetanus toxoid not less than 60 i.u., killed B. pertussis not less than 4 i.u. per 0.5 mL. Haemophilus influenzae type b polysaccharide conjugated to tetanus protein equivalent to 10 micrograms of polysaccharide per 0 .5 mL.
Description Suspension in dual chamber syringe with needle.
Indications Active immunisation against diphtheria, tetanus, pertussis and invasive diseases caused by Haemophilus influenzae type b.
Adult Dosage Not recommended.
Child Dosage Under 2 months, not recommended; two months to four years, three separate injections each of 0 .5 mL by deep subcutaneous or intramuscular injection at minimum of four-week intervals; over four years, not recommended. over four years, not recommended.
Contra Indications Acute illness. History of convulsions, cerebral irritation or damage in the neonatal period. Severe local or general reaction to a preceding dose. Neurological disease, developmental neurological defect.
Special Precautions History of familial epilepsy.
Adverse Drug Reactions Injection site reactions, fever, irritability, persistent crying, loss of appetite, headache, malaise, somnolence, allergic reactions, neurological effects.
