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Drug Details

MALOPRIM

• Drug Class Description
  Sulphones / diaminopyrimidines (antimalarials).
• Generic Name
  Dapsone, pyrimethamine
• Presentation
  Tablets, dapsone 100 mg , pyrimethamine 12.5 mg.
• Description
  White scored tablets marked WELLCOME H9A.
• Indications
  Prophylaxis of malaria.
• Adult Dosage
  1 weekly.
• Child Dosage
  Under 5 years, not applicable; 5  Under 5 years, not applicable; 5 - 10 years, half adult dose; over 10 years, same as adult. Maintain therapy for 4 weeks after leaving area.
• Special Precautions
  

  Not suitable for the treatment of dermatitis herpetiformis. Lactation. Hepatic or renal impairment. Give folate supplements in pregnancy and other deficiency states.

• Interactions
  Folate inhibitors, rifampicin, probenecid.
• Adverse Drug Reactions
  Blood disorders. Acute haemolysis and skin sensitivity.