Search The Medical Knowledge Base

Drug Details

CALSYNAR

• Drug Class Description
  Hormones (synthetic calcitonin).
• Generic Name
  Salcatonin [calcitonin (salmon)] - endocrine
• Presentation
  Injection, salcatonin 100 i.u./ mL.
• Description
  1 mL ampoules or 2 mL multidose vial.
• Indications
  Paget's disease. Postmenopausal osteoporosis. Osteolytic hypercalcaemia of malignancy. Metastatic bone pain.
• Adult Dosage
  

  Paget's disease, 50 i.u. three times weekly to 100 i.u. daily in single or divided doses by subcutaneous or intramuscular injection.

  Postmenopausal osteoporosis, 100 i.u. daily by subcutaneous or intramuscular injection. Patients should also receive 600 mg elemental calcium and 400 units vitamin D daily.

  Hypercalcaemia, initially 400 i.u. six or eight hourly by subcutaneous or intramuscular injection; maximum 8 i.u./kg every 6 hours. Metastatic bone pain, 200 i.u.

  Metastatic bone pain, 200 i.u. six hourly or 400 i.u. 12 hourly by subcutaneous or intramuscular injection for two days.

• Child Dosage
  Not recommended for periods of more than a few weeks; see data sheet.
• Special Precautions
  History of allergy - perform scratch test. Pregnancy and lactation.
• Interactions
  Cardiac glycosides.
• Adverse Drug Reactions
  Nausea, vomiting, flushing, tingling hands, unpleasant taste. Allergic reactions.