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Drug Details

NEO MERCAZOLE

• Drug Class Description
  Antithyroid agents.
• Generic Name
  Carbimazole
• Presentation
  Tablets, carbimazole 5 mg , 20 mg .
• Description
  Pink tablets marked Neo 5 or Neo 20.
• Indications
  Thyrotoxicosis.
• Adult Dosage
  

  Initially, 20 - 60 mg daily in two or three divided doses until patient is euthyroid.

  Maintenance, 5 - 15 mg daily for 6 - 18 months. Alternatively, continue with 20 - 60 mg daily and supplemental thyroxine (levothyroxine) 50 - 150 micrograms daily for 6 - 18 months.

• Child Dosage
  Initially, 15 mg daily in divided doses.
• Contra Indications
  Lactation. Previous history of adverse reactions to carbimazole.
• Special Precautions
  

  Liver disorders. Pregnancy.

• Interactions
  Radio-iodine.
• Adverse Drug Reactions
  

  Rashes, GI upset, headache, arthralgia, alopecia. Bone marrow depression - advise patients to inform you of sore throats, mouth ulcers, pyrexia; withdraw drug. Liver disorders; withdraw drug. Rarely reported, pancytopenia/ aplastic anaemia and isolated thrombocytopenia.