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Drug Details

IBUGEL FORTE 10

• Drug Class Description
  Non-steroidal anti-inflammatory drugs (topical NSAIDs).
• Generic Name
  Ibuprofen
• Presentation
  Aqueous-alcoholic, non-greasy, fragrance-free, clear or slightly hazy gel.
• Description
  Ibuprofen 10.0% w/w.
• Indications
  

  For the topical treatment of rheumatic and muscular pain, sprains, strains, backache and neuralgia. Ibugel Forte 10% is also indicated for symptomatic relief of pain due to non-serious arthritic conditions.

• Adult Dosage
  

  2 to 5 cm gel (50 to 125 mg ibuprofen) is to be applied to the affected area up to three times daily, or as directed by the physician. The gel should be massaged well into the skin until completely absorbed, and hands washed after use unless being treated.

  Treatment should not normally continue for more than a few weeks, unless recommended to do so by a doctor.

  The same dosage and dosage schedule applies to all age groups, although Ibugel Forte 10% is not normally recommended for use on children under the age of 12 years, unless instructed by the physician.

• Child Dosage
  Under 12 years, not recommended.
• Contra Indications
  

  Not to be used if allergic to any of the ingredients, or in cases of hypersensitivity to aspirin, ibuprofen or related painkillers (including when taken by mouth), especially where associated with a history of asthma, rhinitis or urticaria. Not to be used on broken or damaged skin.

• Special Precautions
  

  To be kept away from the eyes and mucous membranes. Oral NSAIDs, including ibuprofen, can sometimes be associated with renal impairment, aggravation of active peptic ulcers, and can induce allergic bronchial reactions in susceptible asthmatic patients. Although the systemic absorption of topically applied ibuprofen is less than for oral dosage forms, these complications can occur in rare cases. For these reasons, caution should be exercised before prescribing Ibugel Forte 10% for patients with an active peptic ulcer, a history of kidney problems, asthma or intolerance to aspirin or ibuprofen taken orally. Patients should seek medical advice if symptoms worsen or persist.

• Interactions
  

  Non-steroidal anti-inflammatory drugs may interact with blood pressure lowering drugs, and may possibly enhance the effects of anticoagulants, although the chance of either of these occurring with a topically administered preparation is extremely remote. Where aspirin or other NSAID tablets are taken concurrently, it is important to bear in mind that these may increase the incidence of undesirable effects.

• Adverse Drug Reactions
  

  Very rarely, susceptible patients may experience the following side effects with ibuprofen, but these are extremely uncommon when ibuprofen is administered topically. If they occur, treatment should be discontinued:-

  Hypersensitivity: hypersensitivity reactions have been reported following treatment with ibuprofen. These may consist of

  (a) non-specific allergic reactions and anaphylaxis,

  (b) respiratory tract reactivity comprising asthma, aggravated asthma, bronchospasm, or dyspnoea, or

  (c) assorted skin disorders, including rashes of various types, pruritus, urticaria, purpura, angioedema and, less commonly, bullous dermatoses (including epidermal necrolysis and erythema multiforme).

  Renal: renal impairment can occur in patients with a history of kidney problems.

  Gastrointestinal: side effects such as abdominal pain and dyspepsia have been reported.