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Drug Details

Quinine Sulphate

• Drug Class Description
  Quinine.
• Generic Name
  Generic
• Presentation
  Tablets, coated, quinine sulphate 200 mg , 300 mg . Available from APS, Co-Pharma (300mg only), Cox, CP (300mg only), Generics UK (300mg only), Hillcross, Regent.
• Description
  Tablets.
• Indications
  Nocturnal leg cramps.
• Adult Dosage
  200 - 300mg at night.
• Contra Indications
  Haemoglobulinuria, tinnitus, optic neuritis. Hypersensitivity to quinine or quinidine. Myasthenia gravis. Pregnancy.
• Special Precautions
  Atrial fibrillation, conduction defects, heart block. G6PD deficiency. Lactation.
• Interactions
  Halofantrine, mefloquine, cardiac glycosides, antipsychotics, cimetidine. Astemizole and terfenadine. Amiodarone, flecainide.
• Adverse Drug Reactions
  Hypersensitivity reactions, including pruritus, rash and  including pruritus, rash and flushing. Cinchonism manifest by tinnitus, headaches, nausea. Visual disturbances, including blurred vision, photophobia and, in severe cases, optic atrophy. Other central nervous system effects, including deafness, vertigo, sweating, restlessness and confusion, have also been reported. Gastrointestinal effects. Haematological effects, including thrombocytopenia, leukopenia and thrombocytopenic purpura. Rarely, agranulocytosis. Conduction disturbances, ventricular tachycardia and anginal symptoms reported. Hypoglycaemia. Acute renal failure.