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Drug Details

Naftidrofuryl oxalate (Generic)

• Drug Class Description
  Peripheral and cerebral activators (vasodilators).
• Generic Name
  Generic
• Presentation
  Capsule
• Description
  100mg naftidrofuryl oxalate equivalent to 81.0 mg naftidrofuryl and 19.0 mg oxalate.
• Indications
  

  Peripheral vascular disorders
  - intermittent claudication, night cramps, rest pain, incipient gangrene, trophic ulcers, Raynaud's Syndrome, diabetic arteriopathy and acrocyanosis. #

  Cerebral vascular disorders
  - cerebral insufficiency and cerebral atherosclerosis, particularly where these manifest themselves as mental deterioration and confusion in the elderly.

• Adult Dosage
  

  Peripheral vascular disorders - one or two capsules three times daily for a minimum of three months, or at the discretion of the physician.

  Cerebral vascular disorders - one 100mg capsule three times daily for a minimum of three months, or at the discretion of the physician.

  There is no recommended use for children.

  Administration:

  For oral administration. The capsules should be swallowed whole during meals with a sufficient amount of water (minimum) of one glass.

• Child Dosage
  Not recommended.
• Contra Indications
  

  Hypersensitivity to the drug. Patients with a history of hyperoxaluria or recurrent calcium-containing stones.

• Special Precautions
  

  A sufficient amount of liquid should be taken during treatment to maintain an adequate level of diuresis.

• Adverse Drug Reactions
  

  Naftidrofuryl oxalate is normally well tolerated in the dosage recommended. Occasionally nausea, epigastric pain and rashes have been noted.

  Rarely, hepatitis has been reported. Very rarely, calcium oxalate kidney stones have been reported.