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Drug Details

ANGIOPINE

• Drug Class Description
  Calcium-channel blockers (class II calcium antagonists).
• Generic Name
  Nifedipine
• Presentation
  Capsules, nifedipine 5mg , 10mg .
• Description
  Capsules.
• Indications
  Raynaud's phenomenon.
• Adult Dosage
  5 mg every eight hours; maximum 20 mg every eight hours.
• Child Dosage
  Not recommended.
• Contra Indications
  Cardiogenic shock, unstable angina, severe aortic stenosis, within a month of MI. Pregnancy, lactation.
• Special Precautions
  Poor cardiac reserve, heart failure, hepatic impairment, severe hypotension, diabetes, dialysis.
• Interactions
  Antihypertensives, cimetidine, quinidine, digoxin, rifampicin, diltiazem, I.V. magnesium sulphate, grapefruit juice.
• Adverse Drug Reactions
  

  Headache, flushing, dizziness, oedema, tachycardia, hypotension, GI disturbances, lethargy, GI disturbances, lethargy, paraesthesia, skin reactions, myalgia, tremor, visual disturbances, increased urinary frequency, hypersensitivity type jaundice (rare), gingival hyperplasia, gynaecomastia. MI, ischaemic pain (discontinue).