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Drug Details

IMAZIN XL

• Drug Class Description
  Nitrates/antiplatelets (antiplatelet agents, salicylates).
• Generic Name
  Isosorbide mononitrate, aspirin
• Presentation
  Imazin XL, Isosorbide mononitrate 60mg in sustained release form, aspirin 75mg. Imazin XL Forte, Isosorbide mononitrate 60mg in sustained release form, aspirin 150mg.
• Description
  Imazin XL: white tablets marked LD. Imazin XL Forte: white tablets marked HD.
• Indications
  Prophylaxis of angina and prevention of secondary MI.
• Adult Dosage
  Imazin XL: One or two tablets to be taken in the morning. Imazin XL Forte: One to be taken in the morning.
• Child Dosage
  Not recommended.
• Contra Indications
  

  Severe cerebrovascular insufficiency, cerebral haemorrhage, hypotension, hypovolaemia, head injury, marked anaemia, acute MI with low left ventricular filling pressure, ventricular filling pressure, peptic ulceration, bleeding disorders, aspirin / anti- inflammatory induced allergies.

• Special Precautions
  Renal or hepatic insufficiency, glaucoma, hypothyroidism, malnutrition, hypothermia, G-6-PD deficiency. Pregnancy and lactation.
• Interactions
  

  Anticoagulants, oral hypoglycaemics, phenytoin, sodium valproate, metoclopramide, methotrexate, sulphonamides, corticosteroids, NSAIDs, probenacid, antihypertensives, diuretics.

• Adverse Drug Reactions
  Hypotension, headaches, flushing.