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Drug Details

VASCACE (cardiac failure)

• Drug Class Description
  ACE inhibitors.
• Generic Name
  Cilazapril - cardiac failure
• Presentation
  Tablets, cilazapril 0.5mg , 1 mg , 2.5 mg , 5 mg .
• Description
  White, yellow, red or brown oval f-c scored tablets marked CIL and with tablet strength.
• Indications
  Adjunct to digitalis and/or diuretics in chronic heart failure.
• Adult Dosage
  Initially 0 .5 mg once daily under close supervision. Adjust according to response. Maintenance, usually 1 - 2 .5 mg once daily; maximum 5 mg once daily.  Not recommended.
• Contra Indications
  Ascites, angioedema after previous ACE inhibitor therapy. Pregnancy, lactation.
• Special Precautions
  Aortic stenosis, hypertrophic cardiomyopathy or outflow obstruction, haemodialysis, renal or hepatic impairment, salt or volume depletion, surgery anaesthesia.
• Interactions
  K+-sparing diuretics, K+- supplements, NSAIDs, lithium, desensitising preparations, allopurinol, immunosuppressants, cytostatics, corticosteroids, procainamide, antidiabetic agents, neuroleptics, tricyclic antidepressants, antihypertensives.
• Adverse Drug Reactions
  Headache, dizziness, fatigue, dyspepsia, nausea, rash, cough. Rarely angioneurotic oedema (if face or mouth affected, withdraw immediately), pancreatitis, alterations in blood count.