Search The Medical Knowledge Base

Drug Details

KINIDIN DURULES

• Drug Class Description
  Class I antiarrhythmics (anti- arrhythmics).
• Generic Name
  Quinidine
• Presentation
  Tablets, quinidine bisulphate 250mg .
• Description
  250 mg white sustained-release tablets.
• Indications
  Maintenance of sinus rhythm following cardioversion of atrial fibrillation. Suppression of supraventricular and ventricular tachyarrhythmias.  tachyarrhythmias.
• Adult Dosage
  1 initially then 2 - 5 twice daily.
• Child Dosage
  Not recommended.
• Contra Indications
  

  Uncompensated cardiac failure, Incomplete AV block, digitalis toxicity, myocarditis, severe myocardial damage. Myasthenia gravis, history of quinidine induced thrombocytopenia or complete heart block. Pregnancy.

• Special Precautions
  

  Monitor patient after first dose for hypersensitivity reactions. Prolonged AV conduction, sustained cardiac decompensation, cardiogenic shock, hypotension, bradycardia, hypokalaemia, oesophageal obstruction.

• Interactions
  

  Digoxin, digitoxin,coumarin derivatives cimetidine, rifampicin, barbiturates, phenytoin, verapamil, amiodarone, nifedipine, desipramine, imipramine, procainamide, metoprolol.

• Adverse Drug Reactions
  GI upset, arrhythmias, hypotension, bradycardia, cinchonism, hypersensitivity reactions.