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Drug Details

ARAMINE

• Drug Class Description
  Sympathomimetics (sympathomimetic amines).
• Generic Name
  Metaraminol
• Presentation
  Injection, metaraminol (as tartrate) 10mg/mL.
• Description
  Clear, colourless, sterile solution for injection in ampoules.
• Indications
  Treatment of acute hypotension due to loss of vasoconstrictor tone as may occur during spinal anaesthesia and as an adjunct to accepted remedial procedures.
• Adult Dosage
  Aramine Injection may be given by either intravenous infusion or direct intravenous injection. Refer to Summary of Product Characteristics.
• Child Dosage
  Not to be used in children.
• Contra Indications
  

  Aramine injection should not be used concurrently with cyclopropane or halothane anaesthesia, unless clinical circumstances demand it. Hypersensitivity to sulphites or any other component of product. Not to be used in children.

• Special Precautions
  

  Pregnancy and lactation.

• Interactions
  Digitalis, MAOIs.
• Adverse Drug Reactions
  

  Sinus or ventricular tachycardia, or other arrhythmias may occur, especially in patients with myocardial infarction. Rarely, abscess formation, tissue necrosis and sloughing may follow use of Aramine.