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Drug Details

Xatral XL 10mg (BPH)

Drug Class Description
Uroselective a1 -blocker (alpha- blockers / alpha-adrenoceptor blocking drugs).
Generic Name
Alfuzosin
Presentation
Tablets, alfuzosin hydrochloride 10mg .
Description
Prolonged release tablets.
Indications
Benign prostatic hypertrophy. (BPH)
Adult Dosage

Xatral XL should be swallowed whole.

BPH: The recommended dose is one 10mg tablet to be taken once daily after a meal.

AUR: In patients 65 years and older, one 10 mg tablet daily after a meal to be taken from the first day of catheterisation. The treatment should be administered for 3-4 days, 2-3 days during catheterisation and 1 day after its removal. In this indication no benefit has been established in patients under 65 years of age or if treatment is extended beyond 4 days.

Paediatric Population

Efficacy of Xatral XL has not been demonstrated in children aged 2 to 16 years. Therefore Xatral XL is not indicated for use in the paediatric population.
Child Dosage
Efficacy of Xatral XL has not been demonstrated in children aged 2 to 16 years. Therefore Xatral XL is not indicated for use in the paediatric population.
Elderly Dosage
In patients 65 years and older, one 10 mg tablet daily after a meal to be taken from the first day of catheterisation. The treatment should be administered for 3-4 days, 2-3 days during catheterisation and 1 day after its removal. In this indication no benefit has been established in patients under 65 years of age or if treatment is extended beyond 4 days.
Contra Indications
Hypersensitivity to alfuzosin. History of orthostatic hypotension. Co-administration with other alpha-blockers. Severe hepatic insufficiency.
Special Precautions
Renal or hepatic impairment. Hypertension; monitor BP regularly, particularly at start of treatment. Coronary insufficiency; discontinue if angina deteriorates. Withdraw 24 hours before anaesthesia.
Interactions
Other a-blockers, antihypertensives. antihypertensives.
Adverse Drug Reactions
Faintness, vertigo, dizziness or malaise, headache, GI upset. Also, orthostatic hypotension, syncope, tachycardia, palpitations, chest pain, fatigue, drowsiness, rash, pruritus, flushes, oedema.