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Drug Details

Regulan Lemon/Lime Flavour

• Drug Class Description
  Bulking agents.
• Generic Name
  Ispaghula husk
• Presentation
  Premeasured, single-dose sachets containing a orange flavoured beige, fine ground powder, which when reconstituted with water is intended for administration as an oral solution.
• Description
  Orange Flavour Regulan contains 3.4g of Ispaghula Husk, BP.
• Indications
  For the relief of constipation and for patients who need to increase their daily fibre intake.
• Adult Dosage
  

  The measured dosage should be poured into a glass and 150ml (¼ pint) of cool water, milk, fruit juice or other liquid added, stirred, and taken immediately. Additional liquid may be taken if required. Adequate fluid intake should be maintained.

  Adults and children over 12 years

  Usual dosage is the entire contents of one sachet taken one to three times daily.

  Elderly

  No alteration in dosage necessary.

  Children 6-12 years

  A reduced dosage based upon age of the child should be given. ½ - 1 level teaspoonful one to three times daily.

• Child Dosage
  Under 6 years, not recommended; 6 - 12 years, / - 1 level 5 mL spoonful in water one to three times daily.
• Contra Indications
  

  Not to be given to patients with intestinal obstruction, faecal impaction, colonic atony or hypersensitivity to ispaghula.or any of the ingredients.

  Do not give to children under 6 years of age, unless on the advice of a doctor

• Special Precautions
  

  Orange Flavour Regulan should always be taken as a liquid suspension and should be drunk immediately after mixing. The last dose should not be taken immediately before going to bed since impaired or reduced gastric motility may impair the intestinal passage and then cause sub-obstruction. The drug may cause allergic reactions in people sensitive to inhaled or ingested ispaghula powder or with hypersensitivity to any of the excipients.

  It may be advisable to supervise treatment in the elderly or debilitated and patients with intestinal narrowing or decreased motility, as rare instances of gastrointestinal obstruction have been reported with mucilloid preparations when taken, contrary to the administration instructions, with insufficient liquid.

  Each sachet contains 26mg of phenylalanine and this should be considered in phenylketonuric patients.

  The colouring agent, Sunset Yellow, can cause allergic type reactions including asthma. Allergy is more common in those people who are allergic to aspirin.

• Interactions
  

  There are no known clinical relevant interactions.

• Adverse Drug Reactions
  

  Gastroi ntestinal disorders:

  Regulan (Ispaghula), as with other bulk laxatives, may temporarily increase flatulence and abdominal distension when the product is first used. Other symptoms including nausea, diarrhoea and abdominal discomfort or pain have rarely been reported (<1 in 1000).

  Intestinal obstruction and faecal impaction may occur very rarely (<1 in 10,000), especially if the product is taken with insufficient fluid.

  Immune system disorders:

  There are very rare reports (<1 in 10,000) of allergic or hypersensitivity reactions associated with the ingestion or inhalation of Ispaghula including skin rashes or allergic dermatitis, rhinitis, urticaria, bronchospasm and anaphylactic reactions.