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Drug Details

ZESTORETIC

• Drug Class Description
  ACE inhibitors / thiazide diuretics (thiazides).
• Generic Name
  Lisinopril, hydrochlorothiazide
• Presentation
  Zestoretic 20: Lisinopril (as dihydrate) 20mg, hydrochlorothiazide 12.5mg. Zestoretic 10: Lisinopril (as dihydrate) 10mg, hydrochlorothiazide 12.5mg.
• Description
  Zestoretic 20: white tablets. Zestoretic 10: peach tablets.
• Indications
  

  Mild to moderate hypertension in patients stabilised on the individual components given in the same proportions.

• Adult Dosage
  1 daily. Maximum 2 daily.
• Child Dosage
  Not recommended.
• Contra Indications
  Anuria, angioneurotic oedema related to previous ACE inhibitor therapy, pregnancy, lactation.
• Special Precautions
  Fluid or electrolyte imbalance, ischaemic heart or cerebrovascular disease, haemodialysis, renal or hepatic impairment, gout/hyperuricaemia, diabetes, surgery/anaesthesia.
• Interactions
  K+-supplements, K+-sparing diuretics, lithium, NSAIDs, tubocurarine, hypoglycaemics.
• Adverse Drug Reactions
  Dizziness, headache, cough, fatigue, hypotension, angioneurotic oedema, nausea, impotence, diarrhoea.