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Drug Details

VALCLAIR (epilepsy)

• Drug Class Description
  Long-acting benzodiazepines (anxiolytics, anticonvulsants / anti-epileptics).
• Generic Name
  Diazepam - epilepsy
• Presentation
  Suppositories, diazepam 10 mg .
• Description
  Suppositories.
• Indications
  Adjunctive treatment of epilepsy.
• Adult Dosage
  Up to 60 mg daily in divided doses.
• Child Dosage
  Not recommended.
• Contra Indications
  

  Acute pulmonary insufficiency, respiratory depression, phobic or obsessional states, chronic psychosis, myasthenia gravis. Pregnancy, labour and lactation.

• Special Precautions
  

  Chronic pulmonary insufficiency, chronic renal or hepatic disease. The elderly. Judgement and dexterity may be impaired, patients should be warned of these effects. Do not use alone to treat depression or anxiety associated with depression. In cases of bereavement, psychological adjustment may be impaired. Avoid long-term use; withdraw gradually.

• Interactions
  Alcohol and other CNS depressants, anticonvulsants, narcotic analgesics, cimetidine, rifampicin.
• Adverse Drug Reactions
  

  Drowsiness, light-headedness, muscle weakness, ataxia, confusion, vertigo, GI upset, hypotension, visual disturbances, skin rashes, impaired alertness and dexterity. Urinary retention, changes in libido. Rarely blood disorders and jaundice. Abnormal dependence increases the higher the dose and the longer the treatment.