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Drug Details

ANGIOPINE MR

• Drug Class Description
  Calcium-channel blockers (class II calcium antagonists).
• Generic Name
  Nifedipine - hypertension
• Presentation
  Tablets, nifedipine 10mg , 20mg .
• Description
  10 mg red sustained-release tablets; 20 mg pink sustained- release tablets.
• Indications
  

  Hypertension.

• Adult Dosage
  Initially 10 mg every 12 hours. Titrate according to response; maximum 40 mg in 12 hours.
• Child Dosage
  Not recommended.
• Contra Indications
  Cardiogenic shock, unstable angina, severe aortic stenosis, within a month of MI. Pregnancy, lactation.
• Special Precautions
  Poor cardiac reserve, heart failure, hepatic impairment, severe hypotension, diabetes, dialysis.
• Interactions
  Antihypertensives, cimetidine, quinidine, digoxin, rifampicin, diltiazem, I.V. magnesium sulphate, grapefruit juice.
• Adverse Drug Reactions
  

  Headache, flushing, dizziness, oedema, tachycardia, hypotension, GI disturbances, lethargy, paraesthesia, skin reactions, myalgia, tremor, visual disturbances, increased urinary frequency, hypersensitivity type jaundice (rare), gingival hyperplasia, gynaecomastia. MI, ischaemic pain (discontinue).