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Drug Details

ANGIOPINE LA

• Drug Class Description
  Calcium-channel blockers (class II calcium antagonists).
• Generic Name
  Nifedipine - hypertension
• Presentation
  Tablets, nifedipine 40mg .
• Description
  Modified release tablets.
• Indications
  Hypertension.
• Adult Dosage
  40mg once daily, increasing to 80mg daily if necessary.
• Child Dosage
  Not recommended.
• Contra Indications
  Cardiogenic shock, unstable angina, severe aortic stenosis, within a month of MI. Pregnancy, lactation.
• Special Precautions
  

  Poor cardiac reserve, heart failure, hepatic impairment, severe hypotension, diabetes, dialysis.

• Interactions
  Antihypertensives, cimetidine, quinidine, digoxin, rifampicin, diltiazem, I.V. magnesium sulphate, grapefruit juice.
• Adverse Drug Reactions
  

  Headache, flushing, dizziness, oedema, tachycardia, hypotension, GI disturbances, lethargy, paraesthesia, skin reactions, paraesthesia, skin reactions, myalgia, tremor, visual disturbances, increased urinary frequency, hypersensitivity type jaundice (rare), gingival hyperplasia, gynaecomastia. MI, ischaemic pain (discontinue).