Search The Medical Knowledge Base

Drug Details

Bendrofluazide

• Drug Class Description
  Thiazide diuretics (thiazides).
• Generic Name
  Generic
• Presentation
  Tablets, bendrofluazide 2.5 mg , 5 mg , Available from APS, Ashbourne (Neo-Bendromax R ), Cox, Goldshield (Neo-NaclexR , 5 mg only), Hillcross, Norton, Regent, Sovereign (AprinoxR , generic preparation also available).
• Description
  Tablets.
• Indications
  

  Mild hypertension. Severe hypertension (in combination with other drugs). Mild to moderate other drugs). Mild to moderate heart failure where no pulmonary oedema is present.

• Adult Dosage
  

  Oedema, initially 5 - 10 mg every morning or on alternate days. Maintenance, 5 - 10 mg once or twice weekly. Hypertension, 2.5 - 5 mg once daily.

• Child Dosage
  Initially up to 400 microgram/kg daily reducing to 50 - 100 microgram/kg daily for maintenance.
• Contra Indications
  Severe renal failure. Sulphonamide sensitivity. Lactation.
• Special Precautions
  

  Hepatic or renal impairment, Addison's disease, hypercalcaemia, diabetes, gout, SLE. Monitor renal function and electrolytes. Elderly. Pregnancy.

• Interactions
  

  Lithium, cardiac glycosides, corticosteroids, carbenoxolone, tubocurarine, NSAIDs, antidiabetic agents, alcohol, barbiturates, opioids, antihypertensives.

• Adverse Drug Reactions
  Electrolyte and metabolic disturbance. Rash, photosensitivity, blood dyscrasias, impotence, pancreatitis.