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Drug Details

Acetazolamide (cardiovascular)

• Drug Class Description
  Carbonic anhydrase inhibitors.
• Generic Name
  Generic
• Presentation
  Tablets, acetazolamide 250mg . Available from Regent Labs.
• Description
  Tablets.
• Indications
  Oedema.
• Adult Dosage
  250mg - 375mg once daily.
• Contra Indications
  
  • Hepatic disease or insufficiency
  • Hyponatraemia: hypokalaemia
  • Adrenocortical insufficiency,  hyperchloraemic acidosis, severe renal disease or dysfunction
  • Chronic closed angle glaucoma
  •  Hypersensitivity to sulphonamides
  • Pregnancy.
• Special Precautions
  

  Respiratory acidosis
  Pulmonary obstruction, Emphysema

  Diabetes
  Monitor fluid, electrolytes, blood, Lactation.

• Interactions
  
  • Folic acid antagonists
  • hypoglycaemics
  • oral anticoagulants.
• Adverse Drug Reactions
  

  GI disturbances
  Nnausea, vomiting, diarrhoea;

  CNS disturbances
  Drowsiness, paraesthesia;

  Hypersensitivity reactions
  Blood dycrasias, flushing, thirst, headache, rash. headache, rash.