Lutein supplementation – the potential to intervene on AMD pathology
Carotenoid intake has shown to reduce the risk of severe AMD – thus demonstrating a clear link between dietary supplementation and disease management7
1. Taylor HR, et al. The Long-term Effects of Visible Blue Light on the Eye. Arch Ophthalmol 1992;110:99-104 2. Cruickshanks KJ, et al. Sunlight and age-related macular degeneration. The Beaver Dam Eye Study. Arch Opthalmol 1993;111:514-518. 3. Bernstein PS, et al. Resonance Raman Measurement of Macular Carotenoids in Normal Subjects and in Age-related Macular Degeneration Patients. Ophthalmology 2002;109(10):1780-1787 4. Pratt SG. What We Now Know About AMD and Nutrition. Review of Ophthalmology 1998;08. (www.revophth.com) 5. Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 1995;62(suppl):1448S-1461S 6. Landrum JR, et al. A One Year Study of the Macular Pigment: The Effect of 140 Days of a Lutein Supplement. Exp. Eye Res. 1997;65:57- 7. Seddon et al. Dietary Carotenoids, Vitamins A. C, and E, and Advanced Age-Related Macular Degeneration. JAMA 1994; 272:1413-20.
Lutein supplements – proven efficacy in oxidative stress
Macular pigment loss constitutes a major risk factor in the development of AMD. – Lutein may delay or alter the course of the disease by replenishing this loss2
1. Seddon et al. Dietary Carotenoids, Vitamins A. C, and E, and Advanced Age-Related Macular Degeneration. JAMA 1994; 272:1413-
20. 2. Beatty et al. Macular Pigment and Risk for Age-Related Macular Degeneration in Subjects from a Northern European Population.
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