Sexual Health Medical Journal Abstracts

A national study of the provision of oncology sperm banking services among Canadian fertility clinics

European Journal of Cancer Care
Feb 2013

A national study of the provision of oncology sperm banking services among Canadian fertility clinics

The purpose of this study was to survey the current state of oncology sperm banking services provided by fertility clinics across Canada. A total of 78 Canadian fertility facilities were invited to complete a questionnaire related to the availability, accessibility, affordability and utilisation of sperm banking..

A case report of an incidental finding of a 46,XX, SRY-negative male with masculine phenotype during standard fertility workup with review of the literature and proposed immediate and long-term management guidance

Fertility and Sterility
Jan 2013

A case report of an incidental finding of a 46,XX, SRY-negative male with masculine phenotype during standard fertility workup with review of the literature and proposed immediate and long-term management guidance

Objective: To describe and explore the current literature on the rare genetic condition of 46,XX SRY-negative males. In addition, we propose comprehensive clinical guidelines in the management of this condition to aid fertility clinicians in their management of affected individuals. Design: Case report with expert..

Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization and intracytoplasmic sperm injection?

Fertility and Sterility
Jan 2013

Are sperm DNA fragmentation, hyperactivation, and hyaluronan-binding ability predictive for fertilization and embryo development in in vitro fertilization and intracytoplasmic sperm injection?

Objective: To determine the diagnostic value of the following sperm function tests in predicting the fertilizing ability of spermatozoa in conventional in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI): hyaluronan-binding assay (HBA), DNA fragmentation (Halosperm), and hyperactivity. Design:..

Biomarkers for ectopic pregnancy and pregnancy of unknown location

Fertility and Sterility
Jan 2013

Biomarkers for ectopic pregnancy and pregnancy of unknown location

Early pregnancy failure is the most common complication of pregnancy, and 1% to 2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum..

Consecutive GnRH-antagonist IVF cycles: does the elapsed time interval between successive treatments affect outcomes?

Fertility and Sterility
Jan 2013

Consecutive GnRH-antagonist IVF cycles: does the elapsed time interval between successive treatments affect outcomes?

Objective: To determine whether patients who failed an IVF cycle can proceed with a subsequent IVF cycle after waiting only one menstrual cycle, or whether there is a benefit to allowing two or more menstrual cycles to elapse before proceeding. Design: Retrospective cohort study. Setting: Academic medical center...

Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation

Fertility and Sterility
Jan 2013

Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation

Objective: To investigate the effects of cryoprotectants on the expression of AQP7 in oocytes. Design: Experimental animal study. Setting: University-based research laboratory. Animal(s): Adult female C57BL/6J mice. Intervention(s): In metaphase II (MII) oocytes obtained from adult female C57BL/6J mice and from..

Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis

Fertility and Sterility
Jan 2013

Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis

Objective: To identify the impact of the pluripotent transcription factor OCT4 in endometrial cell migration and endometriosis. Design: The OCT4 expression and cell migration study. Setting: Research institution and reproductive medical clinic. Patient(s): Nine subjects with normal endometrium, 3 subjects with normal..

Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach

Fertility and Sterility
Jan 2013

Prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach

Objective: To estimate the prevalence of infertility using a current duration approach for comparison with a traditional constructed measure. Design: Cross-sectional survey. Setting: Not applicable. Patient(s): A nationally representative sample of females aged 15–44 years. Intervention(s): None. Main Outcome..

Gender differences in factors influencing sexual satisfaction in Korean older adults

Archives of Gerontology and Geriatrics
Nov 2012

Gender differences in factors influencing sexual satisfaction in Korean older adults

This study investigates the sex lives of Korean older adults (i.e., those over 60 years) and attempts to identify gender-related factors influencing sexual satisfaction. It used data from the 2008 Korean National Survey on Older Adults conducted by the Ministry of Health, Welfare, and Families. Of the 15,146..

Warts and all: Human papillomavirus in primary immunodeficiencies

Journal of Allergy and Clinical Immunology
Oct 2012

Warts and all: Human papillomavirus in primary immunodeficiencies

Infection with human papillomavirus (HPV) is almost universal and eventually asymptomatic, but pathologic infection with HPV is severe, recurrent, and recalcitrant to therapy. It is also an underappreciated manifestation of primary immunodeficiency. Mutations in EVER1, EVER2, GATA2, CXCR4, and dedicator of cytokinesis..

Systematic selection of screening participants by risk score in a chlamydia screening programme is feasible and effective

Sexually Transmitted Infections
Jan 2012

Systematic selection of screening participants by risk score in a chlamydia screening programme is feasible and effective

Objectives: Systematic screening for Chlamydia trachomatis by individual invitation can be optimised by filtering participants on risk profile, excluding people at no or low risk. The authors investigated this technique in a large-scale chlamydia screening programme in the Netherlands in one rural region where..

The cost and cost-effectiveness of opportunistic screening for Chlamydia trachomatis in Ireland

Sexually Transmitted Infections
Jan 2012

The cost and cost-effectiveness of opportunistic screening for Chlamydia trachomatis in Ireland

Objective: The objective of this study was to estimate the cost and cost-effectiveness of opportunistic screening for Chlamydia trachomatis in Ireland. Methods: Prospective cost analysis of an opportunistic screening programme delivered jointly in three types of healthcare facility in Ireland. Incremental..

Core Sexual/Reproductive Health Care to Deliver to Male Adolescents: Perceptions of Clinicians Focused on Male Health

Journal of Adolescent Health
Dec 2011

Core Sexual/Reproductive Health Care to Deliver to Male Adolescents: Perceptions of Clinicians Focused on Male Health

Purpose: Male adolescents experience adverse sexual/reproductive health (SRH) outcomes, yet few providers deliver male SRH care. Given the lack of evidence base for male SRH care, the purpose of this study was to examine perceived importance in delivering SRH care to male adolescents among clinicians focused on male..

Beyond Age at First Sex: Patterns of Emerging Sexual Behavior in Adolescence and Young Adulthood

Journal of Adolescent Health
Nov 2011

Beyond Age at First Sex: Patterns of Emerging Sexual Behavior in Adolescence and Young Adulthood

Purpose: Although the emergence of sexual expression during adolescence and early adulthood is nearly universal, little is known about patterns of initiation. Methods: We used latent class analysis to group 12,194 respondents from waves I and IV of the National Longitudinal Study of Adolescent Health (Add Health) into..

The association of depression, risky sexual behaviours and herpes simplex virus type 2 in adults in NHANES, 2005–2008

Sexually Transmitted Infections
Nov 2011

The association of depression, risky sexual behaviours and herpes simplex virus type 2 in adults in NHANES, 2005–2008

Objectives: Depression has been linked to risky sexual behaviours in adolescents, but there is little research among adults. The goal of this analysis was to examine the associations between current depression and self-reported risky sexual behaviours in a nationally representative sample of US adults aged 20–59 years...

Comparative performance of culture using swabs transported in Amies medium and the Aptima Combo 2 nucleic acid amplification test in detection of Neisseria gonorrhoeae from genital and extra-genital sites: a retrospective study

Sexually Transmitted Infections
Oct 2011

Comparative performance of culture using swabs transported in Amies medium and the Aptima Combo 2 nucleic acid amplification test in detection of Neisseria gonorrhoeae from genital and extra-genital sites: a retrospective study

Background: Nucleic acid amplification tests are being increasingly used for the routine diagnosis of Neisseria gonorrhoeae (GC), although culture remains essential for monitoring antimicrobial resistance. The authors investigated how symptoms and infection site influenced test sensitivity. Methods: This was a..

Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal, Brazil

Molecular Medicine Reports
Sep 2011

Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal, Brazil

This study analyzed the prevalence of human papillomavirus (HPV) in cervical specimens obtained from women with normal cytology and with cervical cancer, in order to evaluate their correlation with health status and demographic characteristics, as well as sexual and reproductive activity in women treated at a cancer..

The Direct Medical Costs of Late Presentation (<350/mm) of HIV Infection over a 15-Year Period.

AIDS Research and Treatment
Aug 2011

The Direct Medical Costs of Late Presentation (<350/mm) of HIV Infection over a 15-Year Period.

We describe the immediate- and longer-term direct medical costs of care for individuals diagnosed with HIV at CD4 counts <350/mm3 (“late presenters”). We collected and stratified by initial CD4 count all inpatient, outpatient, and drug costs for all newly diagnosed patients accessing HIV care within Southern Alberta..

Risk Factors Associated with False Positive HIV Test Results in a Low-Risk Urban Obstetric Population

Journal of Pregnancy
Aug 2011

Risk Factors Associated with False Positive HIV Test Results in a Low-Risk Urban Obstetric Population

Objective: To examine risk factors for false positive HIV enzyme immunoassay (EIA) testing at delivery. Study Design. A review of pregnant women who delivered at Parkland Hospital between 2005 and 2008 was performed. Patients routinely received serum HIV EIA testing at delivery, with positive results confirmed through..
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