Radiology Medical Journal Abstracts

Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence

Lung Cancer
May 2013

Activation of p53 with Nutlin-3a radiosensitizes lung cancer cells via enhancing radiation-induced premature senescence

Radiotherapy is routinely used for the treatment of lung cancer. However, the mechanisms underlying ionizing radiation (IR)-induced senescence and its role in lung cancer treatment are poorly understood. Here, we show that IR suppresses the proliferation of human non-small cell lung cancer (NSCLC) cells via an..

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Sonographic joint assessment in rheumatoid arthritis: Associations with clinical joint assessment in remission

Arthritis & Rheumatism
May 2013

Sonographic joint assessment in rheumatoid arthritis: Associations with clinical joint assessment in remission

Background: Sonography is a sensitive tool for evaluating synovitis in rheumatoid arthritis (RA) compared with clinical assessment. However, differences between these assessments may depend on how “joint activity” is defined. Therefore, we compared clinically vs. sonographically active joints in RA by different..

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Risk factors for predicting the occult nodal metastasis in T1–2N0M0 NSCLC patients staged by PET/CT: Potential value in the clinic

Lung Cancer
May 2013

Risk factors for predicting the occult nodal metastasis in T1–2N0M0 NSCLC patients staged by PET/CT: Potential value in the clinic

Risk factors for predicting the occult nodal metastasis in T1–2N0M0 NSCLC patients staged by PET/CT: Potential value in the clinic..

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Continuous imaging of esophago-gastric junction in patients with reflux esophagitis using 320-row area detector CT: a feasibility study

Journal of Gastroenterology and Hepatology
May 2013

Continuous imaging of esophago-gastric junction in patients with reflux esophagitis using 320-row area detector CT: a feasibility study

Background and Aim: The function of the lower esophageal sphincter (LES) is evaluated using an esophageal manometric study. However, information regarding the surrounding organs is difficult to obtain with use of a sensor catheter. We investigated the utility of 320-row area detector computed tomography (CT) to..

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Prospective evaluation of reliability of cone beam computed tomography in detecting different position of vibroplasty middle ear implants

Clinical Otolaryngology
May 2013

Prospective evaluation of reliability of cone beam computed tomography in detecting different position of vibroplasty middle ear implants

Objectives: This study had the following objectives: (i) To determine the accuracy of determination of Vibrant Soundbridge position in the spectrum of typically implanted sites in the middle ear. (ii) To assess inter-observer agreement between 3 observers with different levels of radiology experience. (iii) To..

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A Multicenter Study of the Risk of Intra-Abdominal Injury in Children After Normal Abdominal Computed Tomography Scan Results in the Emergency Department

Annals of Emergency Medicine
Apr 2013

A Multicenter Study of the Risk of Intra-Abdominal Injury in Children After Normal Abdominal Computed Tomography Scan Results in the Emergency Department

Study objective: We determine whether intra-abdominal injury is rarely diagnosed after a normal abdominal computed tomography (CT) scan result in a large, generalizable sample of children evaluated in the emergency department (ED) after blunt torso trauma. Methods: This was a planned analysis of data collected during a..

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Doppler study of the fetal vertebral and middle cerebral arteries in fetuses with normal and increased umbilical artery resistance indices

Journal of Clinical Ultrasound
Dec 2012

Doppler study of the fetal vertebral and middle cerebral arteries in fetuses with normal and increased umbilical artery resistance indices

Objective: To compare the brain sparing mechanism of the fetal vertebral artery (VA), with the one of the middle cerebral artery (MCA) in fetuses with increased umbilical artery (UA) Doppler impedance. Method: We retrospectively studied 1084 Doppler examinations of the VA, MCA and UA performed in 1084 fetuses between..

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Automated liver stiffness measurements with magnetic resonance elastography

Journal of Magnetic Resonance Imaging
Dec 2012

Automated liver stiffness measurements with magnetic resonance elastography

Purpose: To provide a fully automated algorithm for obtaining stiffness measurements from hepatic magnetic resonance elastography (MRE) images that are consistent with measurements performed by expert readers. Materials and Methods: An initial liver contour was found using an adaptive threshold and expanded using an..

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Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM

Journal of Magnetic Resonance Imaging
Dec 2012

Comparison of DSC-MRI post-processing techniques in predicting microvascular histopathology in patients newly diagnosed with GBM

Purpose: To evaluate which common post-processing method applied to gradient-echo DSC-MRI data, acquired with a single gadolinium injection and low flip-angle, most accurately reflects microvascular histopathology for patients with de novo, treatment-naive glioblastoma multiforme (GBM). Materials and Methods:..

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Direct in vitro comparison of six three-dimensional positive contrast methods for susceptibility marker imaging

Journal of Magnetic Resonance Imaging
Dec 2012

Direct in vitro comparison of six three-dimensional positive contrast methods for susceptibility marker imaging

Purpose: To compare different techniques for positive contrast imaging of susceptibility markers with MRI for three-dimensional visualization. As several different techniques have been reported, the choice of the suitable method depends on its properties with regard to the amount of positive contrast and the desired..

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Gadoxetic acid-enhanced MRI with MR cholangiography for the preoperative evaluation of bile duct cancer

Journal of Magnetic Resonance Imaging
Dec 2012

Gadoxetic acid-enhanced MRI with MR cholangiography for the preoperative evaluation of bile duct cancer

Purpose: To assess the diagnostic accuracy of gadoxetic acid-enhanced biliary MRI with MR cholangiography (MRC) in the preoperative evaluation of bile duct cancer (BDC) staging and resectability. Materials and Methods: Seventy-three patients with BDC who underwent gadoxetic acid-enhanced biliary MRI and MRC, were..

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Role of diffusion-weighted magnetic resonance imaging in the diagnosis of gallbladder cancer

Journal of Magnetic Resonance Imaging
Dec 2012

Role of diffusion-weighted magnetic resonance imaging in the diagnosis of gallbladder cancer

Purpose: To determine the additional diagnostic value of high b-value diffusion-weighted imaging (DWI) compared to conventional biliary magnetic resonance imaging (MRI) for differentiating gallbladder (GB) cancer from benign GB diseases with wall thickening. Materials and Methods: Thirty-nine patients with GB cancers..

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MRI features of the complete histopathological response of locally advanced rectal cancer to neoadjuvant chemoradiotherapy

Clinical Radiology
Jan 2012

MRI features of the complete histopathological response of locally advanced rectal cancer to neoadjuvant chemoradiotherapy

Aim: To describe the post-chemoradiotherapy magnetic resonance imaging (MRI) features of locally advanced rectal carcinoma (LARC) in which there has been a complete histopathological response to neoadjuvant chemoradiotherapy (CRT). Materials and methods: This retrospective cohort study was performed between January..

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Hepatic Venous Pressure Measurements: Comparison of End-Hole and Balloon Catheter Methods

Journal of Vascular and Interventional Radiology
Dec 2011

Hepatic Venous Pressure Measurements: Comparison of End-Hole and Balloon Catheter Methods

Purpose: To determine the difference in hepatic venous pressures measured with the use of an end-hole diagnostic catheter versus a balloon catheter. Materials and Methods: A total of 92 patients underwent transjugular hepatic venous pressure measurements with a 5-F diagnostic end-hole catheter and a balloon catheter,..

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In Vivo Evaluation of Cisplatin-Loaded Superabsorbent Polymer Microspheres for Use in Chemoembolization of VX2 Liver Tumors

Journal of Vascular and Interventional Radiology
Dec 2011

In Vivo Evaluation of Cisplatin-Loaded Superabsorbent Polymer Microspheres for Use in Chemoembolization of VX2 Liver Tumors

Purpose: To investigate the pharmacokinetics and efficacy of chemoembolization with a cisplatin-loaded superabsorbent polymer (SAP) suspension in a rabbit model with transplanted liver VX2 tumors. Materials and Methods: VX2 tumors were implanted into the left lobe of the liver in eight rabbits. Embolization of the..

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Diagnostic accuracy of MRI in adults with suspect brachial plexus lesions: A multicentre retrospective study with surgical findings and clinical follow-up as reference standard

European Journal of Radiology
Nov 2011

Diagnostic accuracy of MRI in adults with suspect brachial plexus lesions: A multicentre retrospective study with surgical findings and clinical follow-up as reference standard

Objective: To evaluate brachial plexus MRI accuracy with surgical findings and clinical follow-up as reference standard in a large multicentre study. Materials and methods: The research was approved by the Institutional Review Boards, and all patients provided their written informed consent. A multicentre retrospective..

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Magnetic resonance imaging assessment of intraventricular dyssynchrony and delayed enhancement as predictors of response to cardiac resynchronization therapy in patients with heart failure of ischaemic and non-ischaemic etiologies

European Journal of Radiology
Nov 2011

Magnetic resonance imaging assessment of intraventricular dyssynchrony and delayed enhancement as predictors of response to cardiac resynchronization therapy in patients with heart failure of ischaemic and non-ischaemic etiologies

Purpose: To assess the value of dyssynchrony and myocardial viability assessment by cardiac magnetic resonance (CMR) in prediction of response to cardiac resynchronization therapy (CRT) in patients with heart failure (HF) of both ischaemic and non-ischaemic etiologies. Materials and methods: Patients scheduled for CRT..

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Structural and functional cerebral impairments in cirrhotic patients with a history of overt hepatic encephalopathy

European Journal of Radiology
Nov 2011

Structural and functional cerebral impairments in cirrhotic patients with a history of overt hepatic encephalopathy

Objective: Diffuse brain atrophy has been observed in cirrhotic patients and recent reports have revealed the persistence of cognitive impairment after clinical resolution of overt hepatic encephalopathy. We sought to explore the continued influence of overt hepatic encephalopathy on neurological function by measuring..

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Urgent radiotherapy is effective in the treatment of metastatic medulloblastoma causing symptomatic brainstem edema

Pediatric Blood & Cancer
Jul 2011

Urgent radiotherapy is effective in the treatment of metastatic medulloblastoma causing symptomatic brainstem edema

A 3-year-old male who presented with hydrocephalus symptoms was found to have metastatic medulloblastoma with diffuse spinal disease. Thirteen days following surgical resection of his primary tumor, he clinically deteriorated due to worsening brainstem edema. Following intubation, stress-dose steroids, and mannitol,..

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Role of dynamic MRI in differentiating benign from malignant follicular thyroid nodule

Auris Nasus Larynx
May 2011

Role of dynamic MRI in differentiating benign from malignant follicular thyroid nodule

Objectives: Thyroid nodular swellings are very common, consisting of both benign and malignant ones. Fine needle aspiration cytology is an excellent diagnostic modality for papillary cancers, medullary cancers, colloid goiter and lymphoma but fails in differentiating follicular adenomas from carcinomas. The purpose of..

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Management of intraoral needle migration into the posterior cervical space

Auris Nasus Larynx
Feb 2011

Management of intraoral needle migration into the posterior cervical space

Foreign bodies within the deep spaces of the neck pose infrequent but substantial risks involving migration, including infection, pseudoaneurysm formation, pneumothorax, hemopericardium, and embolization to the central circulation. A rare case of foreign body migration through the parapharyngeal space into the..

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