Pain Management Medical Journal Abstracts
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The role of circulating sex hormones in menstrual cycle dependent modulation of pain-related brain activation
Pain
Jan 2013
The role of circulating sex hormones in menstrual cycle dependent modulation of pain-related brain activation
Sex differences in pain sensitivity have been consistently found but the basis for these differences is incompletely understood. The present study assessed how pain-related neural processing varies across the menstrual cycle in normally cycling, healthy females, and whether menstrual cycle effects are based on..The pattern and time course of somatosensory changes in the human UVB sunburn model reveal the presence of peripheral and central sensitization
Pain
Jan 2013
The pattern and time course of somatosensory changes in the human UVB sunburn model reveal the presence of peripheral and central sensitization
The UVB sunburn model was characterized with a comprehensive battery of quantitative sensory testing (QST). Primary hyperalgesia in UVB-irradiated skin and secondary hyperalgesia in adjacent, non-irradiated skin were studied in 22 healthy subjects 24 h after irradiation with UVB at 3–fold minimal erythema dosis of a..Cognitive Behavioral Therapy, Self-Efficacy, and Depression in Persons with Chronic Pain
Pain Management Nursing
Jan 2013
Cognitive Behavioral Therapy, Self-Efficacy, and Depression in Persons with Chronic Pain
Chronic pain is a complex and often disabling condition compounded by depression and poor self-efficacy. The purpose of this evidence-based project was to explore the relationship of cognitive behavioral therapy (CBT)–focused groups with self-efficacy and depression in persons with chronic pain at an intensive..Jordanian Patients' Satisfaction with Pain Management
Pain Management Nursing
Jan 2013
Jordanian Patients' Satisfaction with Pain Management
Pain is still undertreated among hospitalized patients. Recently, patient satisfaction with pain management has received significant attention. This field has not yet been explored among Jordanian patients. The purpose of this study was to determine the knowledge regarding pain characteristics, beliefs, and..The Effect of a Program to Promote Play to Reduce Children's Post-Surgical Pain: With Plush Toys, It Hurts Less
Pain Management Nursing
Jan 2013
The Effect of a Program to Promote Play to Reduce Children's Post-Surgical Pain: With Plush Toys, It Hurts Less
Various nonpharmacological strategies to relieve hospitalized children's pain propose play as a central element. Play is considered an essential resource to improve the negative psychosocial effects of the disease and the hospitalization itself. However, the empirical research of play in health settings has not..The Predictive Value of Attentional Bias Towards Pain-Related Information in Chronic Pain Patients: A Diary Study
Pain
Jan 2013
The Predictive Value of Attentional Bias Towards Pain-Related Information in Chronic Pain Patients: A Diary Study
Theoretical accounts of chronic pain hypothesize that attentional bias towards pain-related information is a maintaining or exacerbating factor, fuelling further pain, disability and distress. However, empirical research testing this idea is currently lacking. In the present study, we investigated whether attentional..Is the Pain Reducing Effects of Opioid Medication Reliable? A Psychophysical Study of Morphine and Pentazocine Analgesia
Pain
Jan 2013
Is the Pain Reducing Effects of Opioid Medication Reliable? A Psychophysical Study of Morphine and Pentazocine Analgesia
A number of laboratory studies have confirmed the efficacy of opioid medication in reducing pain generated by a number of psychophysical modalities. However, one implicit assumption of clinical and experimental pain testing of analgesics is that the analgesic response is stable and will be comparable across repeated..Chronic Migraine and Chronic Tension-Type Headache Are Associated With Concomitant Low Back Pain: Results of the German Headache Consortium (GHC) Study
Pain
Jan 2013
Chronic Migraine and Chronic Tension-Type Headache Are Associated With Concomitant Low Back Pain: Results of the German Headache Consortium (GHC) Study
Objective: Evaluate the association between low and frequent low back pain and chronic migraine (CM) and chronic tension-type headache (CTTH) in a large, German population-based sample. Methods: Headaches diagnosed according ICHD-2 criteria and categorized according to frequency (episodic 1-14 days/month or chronic 15..Value of the clinical history in the diagnosis of urticaria/angioedema induced by NSAIDs with cross-intolerance
Clinical & Experimental Allergy
Sep 2012
Value of the clinical history in the diagnosis of urticaria/angioedema induced by NSAIDs with cross-intolerance
Background: Multiple NSAID-induced urticaria/angioedema is the most common manifestation of hypersensitivity reactions to NSAIDs. Diagnostic evaluation is based on the clinical history and a drug provocation test. Objective: To evaluate the role of the clinical history in the diagnosis of multiple NSAID-induced..The Pharmacokinetics and Pharmacogenetics of the Antiemetic Cyclizine in Palliative Care Patients
Journal of Pain and Symptom Management
Jan 2012
The Pharmacokinetics and Pharmacogenetics of the Antiemetic Cyclizine in Palliative Care Patients
Context: Cyclizine, an antihistaminic antiemetic, is commonly used in palliative care. Its pharmacokinetics have been poorly studied, and its metabolic pathway is unknown but may involve the genetically controlled cytochrome P450 2D6 (CYP2D6). If this is the case, the metabolic ratio of cyclizine to norcyclizine and..Improving Outcomes for People With Progressive Cancer: Interrupted Time Series Trial of a Needs Assessment Intervention
Journal of Pain and Symptom Management
Jan 2012
Improving Outcomes for People With Progressive Cancer: Interrupted Time Series Trial of a Needs Assessment Intervention
Context: Improving the effectiveness of cancer care delivery has become a major focus of research. Objectives: This study assessed the uptake and impact of the Palliative Care Needs Assessment Guidelines and Needs Assessment Tool: Progressive Disease—Cancer (NAT: PD-C) on the outcomes of people with advanced cancer...Does Health-Related Quality of Life Improve for Advanced Pancreatic Cancer Patients Who Respond to Gemcitabine? Analysis of a Randomized Phase III Trial of the Cancer and Leukemia Group B (CALGB 80303)
Journal of Pain and Symptom Management
Nov 2011
Does Health-Related Quality of Life Improve for Advanced Pancreatic Cancer Patients Who Respond to Gemcitabine? Analysis of a Randomized Phase III Trial of the Cancer and Leukemia Group B (CALGB 80303)
Context: Gemcitabine for advanced pancreatic cancer is palliative and the prognosis is poor, making health-related quality of life (HRQOL) particularly important. Objective: We evaluated HRQOL with the EuroQol (EQ-5D™) in patients with APC participating in Cancer and Leukemia Group B 80303, a multicenter, double-blind,..Intrathecal combination of ziconotide and morphine for refractory malignant pain: A rapidly acting and effective choice
Pain
Nov 2011
Intrathecal combination of ziconotide and morphine for refractory malignant pain: A rapidly acting and effective choice
Ziconotide is a nonopioid intrathecal analgesic drug used to manage moderate to severe chronic pain. The aim of this work is to assess the safety and efficacy of intrathecal (IT) combination of ziconotide and morphine in malignant pain refractory to high doses of oral opioids. Patients with malignant pain refractory to..Unpacking the burden: Understanding the relationships between chronic pain and comorbidity in the general population
Pain
Nov 2011
Unpacking the burden: Understanding the relationships between chronic pain and comorbidity in the general population
We investigated the association of chronic pain with physical and mental comorbidity in the New Zealand population by measuring chronic pain status separate from comorbid conditions. Models of allostatic load provided a conceptual basis for considering multi-morbidity as accumulated comorbid load and for using both..Does fear of movement mediate the relationship between pain intensity and disability in patients following whiplash injury? A prospective longitudinal study
Pain
Nov 2011
Does fear of movement mediate the relationship between pain intensity and disability in patients following whiplash injury? A prospective longitudinal study
The aim of this study was to test the capacity of the Fear Avoidance Model to explain the relationship between pain and disability in patients with whiplash-associated disorders. Using the method of Baron and Kenny [1], we assessed the mediating effect of fear of movement on the cross-sectional and longitudinal..Do non-steroidal anti-inflammatory drugs have a significant effect on detection and grading of ultrasound-detected synovitis in patients with rheumatoid arthritis? Results from a randomised study
Annuals of Rheumatic Diseases
Jul 2011
Do non-steroidal anti-inflammatory drugs have a significant effect on detection and grading of ultrasound-detected synovitis in patients with rheumatoid arthritis? Results from a randomised study
Objectives: To determine whether non-steroidal anti-inflammatory drugs (NSAIDs) have a significant effect on ultrasonographic (US) grey scale (GS) and power Doppler (PD) assessment of synovitis in rheumatoid arthritis (RA). Methods: Patients with RA taking NSAIDs were randomised to either stopping (for a minimum of 5..Presence of neuropathic pain as an underlying mechanism for pain associated with cold weather in patients with sickle cell disease
Medical hypotheses
Jul 2011
Presence of neuropathic pain as an underlying mechanism for pain associated with cold weather in patients with sickle cell disease
Less than 20 years after Herrick described the first case, the cold was proposed as having a role in precipitating pain in sickle cell disease. Numerous publications focus on weather changes, in particular exposure to the cold, and their association with vaso-occlusive (painful) episodes. Whereas several theories have..Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study
Annuals of Rheumatic Diseases
Jun 2011
Lumbar disc degeneration and genetic factors are the main risk factors for low back pain in women: the UK Twin Spine Study
Objective: Low back pain (LBP) is a common musculoskeletal disorder, but it is still unclear which individuals develop it. The authors examined the contribution of genetic factors, lumbar disc degeneration (LDD) and other risk factors in a female sample of the general population. Material and Methods: A cross-sectional..
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