Ear, Nose and Throat Medical Journal Abstracts
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Salvage surgery of vestibular schwannoma after failed radiotherapy: The Gruppo Otologico experience and review of the literature
American Journal of Otolaryngology
Nov 2012
Salvage surgery of vestibular schwannoma after failed radiotherapy: The Gruppo Otologico experience and review of the literature
Objectives: The use of radiation therapy has largely widespread and becomes in many centers the preference modality of treatment for symptomatic patients who are old, medically unfit for surgical therapy, those who refuse surgery and in some recurrent or residual growing tumors. The risk of radiotherapy failure in the..Cognitive behaviour therapy for chronic subjective dizziness: longer-term gains and predictors of disability
American Journal of Otolaryngology
Nov 2012
Cognitive behaviour therapy for chronic subjective dizziness: longer-term gains and predictors of disability
Purpose: The study sought to evaluate the longer-term effects of a brief cognitive behaviour therapy (CBT) intervention for patients with chronic subjective dizziness (CSD). In addition, it sought to identify predictors of longer-term disability in this group. Materials and methods: Forty-four patients with CSD..Design and evaluation of tinnitus synthesis methods: From spectral to spatial matching
American Journal of Otolaryngology
Nov 2012
Design and evaluation of tinnitus synthesis methods: From spectral to spatial matching
Purpose: This study was designed to investigate methods to help patients suffering from unilateral tinnitus synthesizing an auditory replica of their tinnitus. Materials and methods: Two semi-automatic methods (A and B) derived from the auditory threshold of the patient and a method (C) combining a pure tone and a..Contemporary management of pediatric lateral sinus thrombosis: A twenty year review
American Journal of Otolaryngology
Nov 2012
Contemporary management of pediatric lateral sinus thrombosis: A twenty year review
Objectives: A case of pediatric otogenic lateral sinus thrombosis is reported, followed by a substantive literature review. Design: 104 patients were reviewed, culled from published case reports from 1993 to 2011 on the PubMed database. Methods: All full text case reports on the PubMed database from 1993 to 2011 with..Single-blind randomized controlled trial of surfactant vs hypertonic saline irrigation following endoscopic endonasal surgery
International Forum of Allergy & Rhinology
Nov 2012
Single-blind randomized controlled trial of surfactant vs hypertonic saline irrigation following endoscopic endonasal surgery
Background: Recent discussion has revolved around formulations of irrigation in the postoperative functional endoscopic sinus surgery patient, specifically the efficacy of emulsion based nasal irrigations. Methods: Forty adult candidates for endoscopic endonasal surgery with chronic rhinosinusitis (CRS) were..Management of neck metastases in T2N0 lip squamous cell carcinoma
American Journal of Otolaryngology
Nov 2012
Management of neck metastases in T2N0 lip squamous cell carcinoma
Background: Prophylactic neck dissection (PND) is indicated when the chance of occult lymph node metastases from head and neck tumors is significant. There is no consensus regarding which tumor size PND would be indicated in cases of lip cancer. Methods: A total of 139 patients with surgically treated lip cancer were..Response of infantile airway and facial hemangiomas to propranolol in a patient with PHACE syndrome
International Journal of Pediatric Otorhinolaryngology Extra
Nov 2012
Response of infantile airway and facial hemangiomas to propranolol in a patient with PHACE syndrome
PHACE syndrome is a neurocutaneous syndrome defined by posterior fossa malformations (P), hemangiomas (H), arterial anomalies (A), cardiac defects and coarctation of the aorta (C), and eye abnormalities (E). Propranolol is currently first line therapy for treatment of head and neck hemangiomas that cause functional..Intramuscular hemangioma of the scalene musculature masquerading as a paraganglioma: A case series
American Journal of Otolaryngology
Nov 2012
Intramuscular hemangioma of the scalene musculature masquerading as a paraganglioma: A case series
Intramuscular hemangiomas (IMHs) are uncommon benign vascular lesions, which develop in skeletal muscle. Herein, two cases of IMHs involving the cervical scalene musculature are presented. Such lesions are exceedingly rare, and can be difficult to distinguish from vagal paragangliomas based on clinical presentation,..A case of necrotizing sialometaplasia involving bilateral parotid glands
American Journal of Otolaryngology
Nov 2012
A case of necrotizing sialometaplasia involving bilateral parotid glands
Necrotizing sialometaplasia of the parotid gland is infrequent and can be mistaken as a malignant disease. Its etiology is thought to be an insufficient blood supply. Bilateral involvement of this disease in parotid glands has been rarely reported in the English literature. We report a case of necrotizing..Endoscopic craniofacial resection for pediatric esthesioneuroblastoma
International Journal of Pediatric Otorhinolaryngology Extra
Nov 2012
Endoscopic craniofacial resection for pediatric esthesioneuroblastoma
Pediatric esthesioneuroblastomas are rare tumors with only about 100 reported cases. Standard surgical treatment is the open craniofacial resection. Pre-treatment imaging is critical for planning, and surgery remains the primary treatment modality followed by adjuvant therapy. We report a 12-year-old female who..Paranasal sinus cholesterol granuloma: systematic review of diagnostic and management aspects
International Forum of Allergy & Rhinology
Oct 2012
Paranasal sinus cholesterol granuloma: systematic review of diagnostic and management aspects
Background: Cholesterol granuloma (CG) is an expansile, cystic lesion most commonly observed in the temporal bone. CG is rarely encountered in the paranasal sinuses. Given its paucity in this region, the diagnostic and management aspects remain to be elucidated. Methods: Systematic review of the literature yielded 66..Intravenous tranexamic acid and intraoperative visualization during functional endoscopic sinus surgery: a double-blind randomized controlled trial
International Forum of Allergy & Rhinology
Oct 2012
Intravenous tranexamic acid and intraoperative visualization during functional endoscopic sinus surgery: a double-blind randomized controlled trial
Background: Bleeding during endoscopic sinus surgery (ESS) can hinder surgical progress and may be associated with increased complications. Tranexamic acid is an antifibrinolytic that is known to reduce operative bleeding. The current study was designed to assess the effect of adjunctive intravenous tranexamic acid on..Maximal medical therapy for chronic rhinosinusitis: a survey of otolaryngology consultants in the United Kingdom
International Forum of Allergy & Rhinology
Oct 2012
Maximal medical therapy for chronic rhinosinusitis: a survey of otolaryngology consultants in the United Kingdom
Background: The management of chronic rhinosinusitis is based on a trial of “maximal medical therapy” before surgery is considered. Ear-Nose-Throat (ENT) UK consultant members were surveyed to determine the role and variability of UK-wide practices. Methods: A survey was posted to all ENT UK consultant members (n =..The subspecialty of rhinology: a survey of otolaryngology chairmen
International Forum of Allergy & Rhinology
Oct 2012
The subspecialty of rhinology: a survey of otolaryngology chairmen
Background: The past decade has witnessed the emergence of rhinology as a distinct subspecialty within otolaryngology. A critical evaluation of this process is necessary to define the field and to determine the impact of subspecialization on residency education. Methods: An Internet-based survey of otolaryngology..The presentation and clinical significance of sinonasal respiratory epithelial adenomatoid hamartoma (REAH)
International Forum of Allergy & Rhinology
Oct 2012
The presentation and clinical significance of sinonasal respiratory epithelial adenomatoid hamartoma (REAH)
Background: Sinonasal respiratory epithelial adenomatoid hamartoma (REAH) is a benign glandular proliferation with ciliated epithelium. Little is known about REAH, with only a few published case reports appearing since its original description in 1995. Classically described as an isolated polypoid lesion arising from..The presentation and clinical significance of sinonasal respiratory epithelial adenomatoid hamartoma (REAH)
International Forum of Allergy & Rhinology
Oct 2012
The presentation and clinical significance of sinonasal respiratory epithelial adenomatoid hamartoma (REAH)
Background: Sinonasal respiratory epithelial adenomatoid hamartoma (REAH) is a benign glandular proliferation with ciliated epithelium. Little is known about REAH, with only a few published case reports appearing since its original description in 1995. Classically described as an isolated polypoid lesion arising from..Basal lamella relaxing incision improves endoscopic middle meatal access
International Forum of Allergy & Rhinology
Oct 2012
Basal lamella relaxing incision improves endoscopic middle meatal access
Background: Lateralization of the middle turbinate is a commonly cited factor leading to failure of functional endoscopic sinus surgery (FESS). Inadequate medialization during FESS may require repeat intraoperative attempts, and may lead to destabilization and mucosal trauma. A novel technique is described that..Evaluation of domestic and Yucatan swine nasal sinus anatomy as models for future sinonasal research of medications delivered by standard instruments used in functional endoscopic sinus surgery
International Forum of Allergy & Rhinology
Oct 2012
Evaluation of domestic and Yucatan swine nasal sinus anatomy as models for future sinonasal research of medications delivered by standard instruments used in functional endoscopic sinus surgery
Background: There is a need to find an animal model to study new medications to improve mucosal wound healing after functional endoscopic sinus surgery (FESS). Current literature suggests swine as a potential candidate. The lack of information correlating swine computer tomography (CT) and endoscopic sinonasal anatomy..Triple-layer reconstruction technique for large cribriform defects after endoscopic endonasal resection of anterior skull base tumors
International Forum of Allergy & Rhinology
Oct 2012
Triple-layer reconstruction technique for large cribriform defects after endoscopic endonasal resection of anterior skull base tumors
Background: Endoscopic endonasal transcribriform (EET) resection of anterior skull base (ASB) tumors results in large defects that may extend the entirety of the cribriform plate. Endoscopic repair of these cribriform defects can often be challenging. We describe our reconstruction technique for large ASB defects after..Impact of tobacco smoke on chronic rhinosinusitis: a review of the literature
International Forum of Allergy & Rhinology
Jun 2012
Impact of tobacco smoke on chronic rhinosinusitis: a review of the literature
Background: Environmental factors such as inhaled pollutants like cigarette smoke may play a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS). The objectives of this review are to summarize prior studies that describe the correlation between active smoking and secondhand smoke..Risk factors for development of chronic rhinosinusitis in patients with allergic rhinitis
International Forum of Allergy & Rhinology
May 2012
Risk factors for development of chronic rhinosinusitis in patients with allergic rhinitis
Background: Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory condition of the sinonasal cavity. CRS may be preceded by other sinonasal inflammatory diseases including allergic rhinitis (AR). It is unclear what factors may predispose patients with AR to develop CRS. Methods: We performed a retrospective..Risk factors for development of chronic rhinosinusitis in patients with allergic rhinitis
International Forum of Allergy & Rhinology
May 2012
Risk factors for development of chronic rhinosinusitis in patients with allergic rhinitis
Background: Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory condition of the sinonasal cavity. CRS may be preceded by other sinonasal inflammatory diseases including allergic rhinitis (AR). It is unclear what factors may predispose patients with AR to develop CRS. Methods: We performed a retrospective..The effect of augmented real-time image guidance on task workload during endoscopic sinus surgery
International Forum of Allergy & Rhinology
May 2012
The effect of augmented real-time image guidance on task workload during endoscopic sinus surgery
Background: Due to proximity to critical structures, the need for spatial awareness during endoscopic sinus surgery (ESS) is essential. We have developed an augmented, real-time image-guided surgery (ART-IGS) system that provides live navigational data and proximity alerts to the operating surgeon during ablation. We..Corticosteroid nasal irrigations after endoscopic sinus surgery in the management of chronic rhinosinusitis
International Forum of Allergy & Rhinology
May 2012
Corticosteroid nasal irrigations after endoscopic sinus surgery in the management of chronic rhinosinusitis
Background: Inflammatory dysfunction is considered an important part of chronic rhinosinusitis (CRS). Corticosteroid therapy has been widely used in CRS. Effective topical delivery has been previously problematic. The post–endoscopic sinus surgery (ESS) corridor is essential for adequate topical drug access. Devices..Chronic rhinosinusitis symptoms and computed tomography staging: improved correlation by incorporating radiographic density
International Forum of Allergy & Rhinology
Apr 2012
Chronic rhinosinusitis symptoms and computed tomography staging: improved correlation by incorporating radiographic density
Background: Traditional methods for staging of chronic rhinosinusitis (CRS) by computed tomography (CT) have not proven to be predictive of subjective reports of patients' symptoms. An objective measure of CRS severity that correlates well with patients' symptoms, particularly if available from CT data, would be a..Efficacy of the pedicled nasoseptal flap without cerebrospinal fluid (CSF) diversion for repair of skull base defects: incidence of postoperative CSF leaks
International Forum of Allergy & Rhinology
Apr 2012
Efficacy of the pedicled nasoseptal flap without cerebrospinal fluid (CSF) diversion for repair of skull base defects: incidence of postoperative CSF leaks
Background: The advances in endoscopic skull base surgery have led to the resection of increasingly larger cranial base lesions and the creation of larger skull base defects with the potential for increased postoperative high-flow cerebrospinal fluid (CSF) leaks. These concerns led to the development of the..Structured histopathology profiling of chronic rhinosinusitis in routine practice
International Forum of Allergy & Rhinology
Apr 2012
Structured histopathology profiling of chronic rhinosinusitis in routine practice
Background: Tissue eosinophilia in chronic rhinosinusitis (CRS) is a marker of inflammatory disorders recalcitrant to surgical intervention. Eosinophilic chronic rhinosinusitis (ECRS) is traditionally associated with asthma, polyps, aspirin sensitivity, high serum eosinophilia, and elevated immunoglobulin E (IgE)...Endonasal repair of septal perforations using a rotational mucosal flap and acellular dermal interposition graft
International Forum of Allergy & Rhinology
Apr 2012
Endonasal repair of septal perforations using a rotational mucosal flap and acellular dermal interposition graft
Background: The closure of nasal septal perforations can be challenging based on the etiology, location, and method of closure. We report on a novel method of closure for nasal septal perforations using a unilateral mucosal rotational flap and acellular dermal interposition graft. Methods: Twenty patients with nasal..Changing trends in sinus and septal surgery, 2007 to 2009
International Forum of Allergy & Rhinology
Mar 2012
Changing trends in sinus and septal surgery, 2007 to 2009
Background: Sinus surgery remains one of the most commonly performed procedures in the United States, with more than 600,000 patients undergoing sinus operations each year. Advances in our understanding of chronic rhinosinusitis (CRS), as well as the technology used to treat it, has resulted in significant changes in..Structured histopathology profiling of chronic rhinosinusitis in routine practice
International Forum of Allergy & Rhinology
Mar 2012
Structured histopathology profiling of chronic rhinosinusitis in routine practice
Background: Tissue eosinophilia in chronic rhinosinusitis (CRS) is a marker of inflammatory disorders recalcitrant to surgical intervention. Eosinophilic chronic rhinosinusitis (ECRS) is traditionally associated with asthma, polyps, aspirin sensitivity, high serum eosinophilia, and elevated immunoglobulin E (IgE)...Chronic rhinosinusitis symptoms and computed tomography staging: improved correlation by incorporating radiographic density
International Forum of Allergy & Rhinology
Mar 2012
Chronic rhinosinusitis symptoms and computed tomography staging: improved correlation by incorporating radiographic density
Background: Traditional methods for staging of chronic rhinosinusitis (CRS) by computed tomography (CT) have not proven to be predictive of subjective reports of patients' symptoms. An objective measure of CRS severity that correlates well with patients' symptoms, particularly if available from CT data, would be a..Incidence and Outcomes of Stricture Formation Postlaryngectomy
Otolaryngology - Head and Neck Surgery
Dec 2011
Incidence and Outcomes of Stricture Formation Postlaryngectomy
Objective: Postlaryngectomy stricture formation and dysphagia negatively affect quality of life and result in nutritional compromise. Understanding risk factors and successful treatment strategies may improve treatment outcomes. Study Design: Historical cohort study. Setting: Tertiary care medical center. Subjects and..Pharyngeal Stasis of Secretions in Patients with Zenker Diverticulum
Otolaryngology - Head and Neck Surgery
Dec 2011
Pharyngeal Stasis of Secretions in Patients with Zenker Diverticulum
Objective: To determine whether patients with Zenker diverticulum are more likely to have stasis of secretions in the left piriform sinus, on in-office endoscopy, than patients with nonspecific dysphagia. Study Design: A case–control study. Setting: A subspecialty swallowing clinic. Subjects and Methods: All patients..International Forum of Allergy & Rhinology
Otolaryngology - Head and Neck Surgery
Dec 2011
International Forum of Allergy & Rhinology
http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)2042-6984..Proteomics in Ménière disease
Journal of Cellular Physiology
Oct 2011
Proteomics in Ménière disease
Ménière's disease (MD) is a disorder of the inner ear characterized by an insidious onset and aspecific symptoms, such as dizziness, vertigo, tinnitus, and hearing loss, that may become very debilitating. The presence of endolymphatic hydrops is a common feature in MD patients, but the pathophysiology is still largely..An unusual headache: Sphenoiditis in children and adolescents.
International Journal of Pediatric Otorhinolaryngology
Sep 2011
An unusual headache: Sphenoiditis in children and adolescents.
Sphenoid sinus infection is a rare cause of headaches in children and adolescents. Its symptoms are often non-specific and confusing. The diagnosis is made on the history, examination, nasendoscopy, cultures and CT or MRI. Prompt and aggressive medical treatment in the form of parenteral antibiotics and nasal..A comparison of tympanometry with 226Hz and 1000Hz probe tones in children with Down syndrome
International Journal of Pediatric Otorhinolaryngology
Sep 2011
A comparison of tympanometry with 226Hz and 1000Hz probe tones in children with Down syndrome
For children with Down syndrome, the incidence of hearing loss may be as high as 78% [1], therefore the American Academy of Pediatrics recommends regular screening for the presence of hearing abnormalities. Tympanometry is used as an indication of middle ear pathology. In our experience, Down's patients' tympanograms..Elevated Epstein-Barr Virus Seroreactivity Among Unaffected Members of Families With Nasopharyngeal Carcinoma
Journal of Medical Virology
Aug 2011
Elevated Epstein-Barr Virus Seroreactivity Among Unaffected Members of Families With Nasopharyngeal Carcinoma
Serum antibodies to Epstein–Barr virus (EBV) antigens can be used to predict the risk of nasopharyngeal carcinoma (NPC). To investigate whether EBV seropositivity rates were higher among healthy family members from multiplex and sporadic families with NPC (i.e., families with multiple or single cases) compared to the..Podoplanin expression correlates with sentinel lymph node metastasis in early squamous cell carcinomas of the oral cavity and oropharynx
International Journal of Cancer
Feb 2011
Podoplanin expression correlates with sentinel lymph node metastasis in early squamous cell carcinomas of the oral cavity and oropharynx
In patients with early head and neck squamous cell carcinoma (HNSCC), occult lymph node metastasis is difficult to predict by clinical or pathological parameters. However, such parameters are necessary to select patients either for elective neck dissection or the sentinel lymph node (SLN) procedure. The membrane..Allergic rhinitis (AR) in geriatric patients
Archives of Gerontology and Geriatrics
Jan 2011
Allergic rhinitis (AR) in geriatric patients
Allergic rhinitis (AR) can be defined as an inflammatory disease of the nose and the paranasal sinuses, characterized by a specific IgE-mediated hypersensitivity reaction. The aim of this study was to evaluate the correlation between the symptoms of AR and the prick test results in geriatric patients presenting with..
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