Immunology Topic Homepage

Symptomatic Asthma

,Symptomatic Asthma Learning Zone

This educational resource has been developed for healthcare professionals in Europe who are involved in the care of patients with asthma.

Disease Awareness - This section provides background information regarding the impact of symptomatic asthma and potential management strategies.

RCGP-accredited CME - Within the continuing medical education (CME) activity, you can learn about physician perspectives on managing symptomatic asthma in practice. Richard Russell and Thys van der Molen discuss in four sessions:

  1. What is asthma control: Who, why and how many?
  2. Improving asthma control in the community
  3. Current standard asthma treatment
  4. Pros and cons of additional add-on treatment.

One hour towards your CPD will be rewarded upon successful completion of the evaluation questionnaire

SPIRIVA® Respimat® is approved for use in asthma in the European Union, Japan and many other countries. It is currently being reviewed by other regulatory authorities such as the Food & Drug Administration in the United States. The indication varies by country and the educational resource may contain information about medications for which indications may not be approved in your country.

CSU Knowledge Centre

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The Chronic Spontaneous Urticaria (CSU) Knowledge Centre has been developed to address the current lack of early diagnosis of this condition. Urticaria is more common than previously thought and studies suggest chronic urticaria affects up to 1% of the population at any given time with CSU responsible for two-thirds of these cases.

Allergists, immunologists, dermatologists and other healthcare professionals involved in the management of CSU will find a range of content to support you in effectively diagnosing and treating the condition.

In this resource, you will find a disease overview, symposia highlights platform, video channel and additional resources including an events calendar and useful external links.

Psoriasis Knowledge Centre

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Psoriasis is a chronic inflammatory disease affecting approximately 2% of the world’s population. The Psoriasis Knowledge Centre provides dermatologists, family medicine doctors and other healthcare professionals with relevant information including epidemiology, pathophysiology, diagnosis and more.

A treatment section reviews the established treatments available for psoriasis and considers their modes of action, available clinical data and place in the therapeutic pathway.

Rheumatology Trends

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Rheumatoid Arthritis (RA) is a chronic, systemic inflammatory autoimmune disease that affects up to 1% of the adult population across the developing world, including more than 1 million people in the US alone. As a result, RA represents the world’s biggest market for drug treatments, aside from oncology. Currently this market is dominated by two categories of treatment: non-steroidal anti-inflammatory drugs (NSAIDs), and biologic disease-modifying anti-rheumatic drugs (DMARDs). The gold standard of treatment has been an older oral DMARD methotrexate (MTX) which is included in most combination therapies but it is beset by unwelcome side-effects. Now the leading DMARDs target tumour necrosis factor (TNF), a key inflammatory mediator. These have had a major impact on outcomes, due to improved tolerability and efficacy

Clinical Case Studies

Wegener's Granulomatosis and the Small Vessel Pulmonary Vasculitides,

Respiratory Medicine & Allergy: Vasculitis/Rare Diseases

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
41-year-old Asian salesman presented following an episode of haemoptysis in which he expectorated a teaspoonful of fresh blood. For several weeks he had been experiencing influenza-like symptoms with lethargy, low-grade fever, arthralgia, breathlessness on climbing stairs and weight loss.

Sarcoidosis (Radiographic Stage I)

Respiratory Medicine & Allergy: Non granuloma interstitial lung disease

Anne Collett, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
A 35-year-old male Caucasian barrister presented with a four-week history of dry cough, breathlessness and fatigue. There was no past medical history.

Latest News

Medical Videos

An Animation of The Main Roles of the Immune System
An Animation of The Main Roles of the Immune System
An Animation Demonstrating the Role of Natural Killer Cells
An Animation Demonstrating the Role of Natural Killer Cells

Recent Drug Updates

Medical Journal Abstracts on Immunology

Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

Mon 27 Jul 2015 -  Efficacy and Long-Term Safety of a Dengue Vaccine in Regions of Endemic Disease

BACKGROUND: A candidate tetravalent dengue vaccine is being assessed in three clinical trials involving more than 35,000 children between the ages of 2 and 16 years in Asian-Pacific and Latin ...

Low expression of circulating microRNA-328 is associated with poor prognosis in patients with acute myeloid leukemia.

Fri 17 Jul 2015 -  Low expression of circulating microRNA-328 is associated with poor prognosis in patients with acute myeloid leukemia.

Background: Dysregulation of circulating miR-328 has been identified in several tumors and is associated with prognosis of patients. However, the expression pattern of miR-328 and the impact on ...

Medical Images

HIV envelope glycoprotein
HIV envelope glycoprotein
Serial chest X-rays
Serial chest X-rays
Sarcoma on hard palate
Sarcoma on hard palate
Macular rash
Macular rash
Osteomyelitis - X-ray
Osteomyelitis - X-ray
Sarcoma on foot
Sarcoma on foot
Distribution of VZV
Distribution of VZV
Oesophageal candidiasis.
Oesophageal candidiasis.
Enlargement, rupture and healing of lymph nodes
Enlargement, rupture and healing of lymph nodes
Pneumocystis jirovecii pneumonia
Pneumocystis jirovecii pneumonia

Clinical Guidelines

Irritable bowel syndrome in adults: diagnosis and management of irritable bowel syndrome in primary care

Feb 2015

Key aspects of this guideline include establishing a diagnosis; referral into secondary care only..

... after identification of 'red flags' (symptoms and/or features that may be caused by another condition that needs investigation); providing lifestyle advice; drug and psychological interventions; and referral and follow-up.

Guidelines on the management of AL amyloidosis

Oct 2014

The purpose of this guideline is to provide guidance on the management of patients with AL..

... amyloidosis.

Online CME

Biological treatment for inflammatory arthritis

After completing this module, you should be able to: know what biological treatments are, be able to explain to patients how they work, know what conditions they are used for,...

Myasthenia gravis: a guide to diagnosis and treatment

After completing this module you should be able to: make a clinical diagnosis of myasthenia gravis, select appropriate diagnostic tests to confirm your diagnosis, and understand the principles of therapy...

Clinical Trials

GHSG-AFM13 An Open-label, Multicenter Phase II Trial With AFM13 in Patients With Relapsed or Refractory Hodgkin Lymphoma

Wed 17 Dec 2014

The study is designed: - to demonstrate efficacy of AFM13 with an optimized treatment schedule - to decide whether AFM13 warrants further investigation in a phase III clinical ...

Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (FLUGAZA)

Wed 10 Dec 2014

The hypothesis is that the replacement of the standard fludarabine and cytarabine based therapy by azacytidine could result in an improvement of RFS and OS rates in the experimental arm. To fulfill ...

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