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Clinical Case Studies

Candidaemia

Infection: Infections in Critical Care

Thomas Patterson, Professor of Medicine and Infectious Diseases, University of Texas Health Science Center, San Antonio, Texas, USA

Case History
A 23-year-old man who was previously healthy was admitted to the surgical intensive care unit (ICU) following a gunshot wound to the abdomen. Exploratory laparotomy revealed a perforated colon which required a temporary diverting colonostomy.

Difficult Asthma

Respiratory Medicine & Allergy: Obstructive Lung Disease/Small Airways Disease

Lynette Linkson, Specialist Registrars in Respiratory Medicine, Guy's and St Thomas' NHS Foundation Trust, London, UK
Richard Leach, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
A 48-year-old man was referred to the chest clinic with uncontrolled adult-onset asthma and severe persistent cough despite repeated courses of oral steroids. Previously his asthma had been well controlled with a combined inhaled corticosteroid (ICS) and long-acting β2 agonist (LABA).

Medical Videos

An Animation of The Main Roles of the Immune System
An Animation of The Main Roles of the Immune System
An Animation Demonstrating the Role of Natural Killer Cells
An Animation Demonstrating the Role of Natural Killer Cells

Recent Drug Updates

Medical Journal Abstracts on Immunology

Fetal Sex–Based Differences in Maternal Hormones, Angiogenic Factors, and Immune Mediators During Pregnancy and the Postpartum Period

Mon 04 Aug 2014 -  American Journal of Reproductive Immunology

Problem:Several pregnancy complications have disparities based on the sex of the fetus. It is unknown whether the sex of the fetus differentially alters the maternal immune milieu, potentially ...

Expression Profiles of Antimicrobial Peptides in the Genital Tract of Women Using Progesterone Intrauterine Devices Versus Combined Oral Contraceptives

Sat 02 Aug 2014 -  American Journal of Reproductive Immunology

Problem:Sex hormones can influence the immune defenses of the female genital tract (FGT) and its susceptibility to infections. Here we investigated the effect of different hormonal contraceptives on ...

Medical Images

Aspiration Syndrome - CT scan
Aspiration Syndrome - CT scan
Chest radiograph of sickle cell lung disease
Chest radiograph of sickle cell lung disease
Immunocytochemical staining
Immunocytochemical staining
Un-enhanced CT head
Un-enhanced CT head
Molluscum contagiosum
Molluscum contagiosum
Oral hairy leukoplakia
Oral hairy leukoplakia
Pulmonary nodule
Pulmonary nodule
Aspiration Syndrome - radiograph
Aspiration Syndrome - radiograph
Osteoporosis
Osteoporosis
Key events leading up to the era of HAART
Key events leading up to the era of HAART

Clinical Guidelines

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Jun 2014

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of..

... recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each Clinical Practice Guideline includes information about: the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans, response evaluation and follow-up.

The Management of Women with Red Cell Antibodies during Pregnancy

May 2014

The purpose of this guideline is to provide guidance on the management of pregnant women with red..

... cell antibodies predating the pregnancy or those developing antibodies during pregnancy. The guideline also includes the management of fetal anaemia caused by red cell antibodies, as well as the early management of the neonate at risk of anaemia and/or hyperbilirubinaemia. It does not address the management of the pregnant woman with anti-platelet antibodies or other autoimmune or alloimmune antibodies.

Online CME

HIV infection: diagnostic picture tests

After completing this module you should know the common causes of mucocutaneous lesions in patients with HIV infection. You should know how to recognise such lesions and, where appropriate, how...

Implementing Best Practices in the Management of Allergic Diseases

This activity is intended for allergists and other physicians with an interest in allergic diseases. The goal of this activity is to discuss the management of allergic rhinoconjunctivitis and other...

In-Depth Discussion of Key Data on Immunotherapy for Allergic Diseases

This activity is intended for allergists and other physicians with an interest in allergic diseases. The goal of this activity is to discuss the risks and benefits of allergen immunotherapy...

Clinical Trials

An open label extension and safety monitoring study of moderate to severe Ulcerative Colitis patients previously enrolled in Etrolizumab phase III studies

05-09-2014

- Part 1 (OLE): to assess the long-term safety and efficacy of etrolizumab in eligible patients.

- Part 2 (SM): Progressive multifocal leukoencephalopathy (PML) safety monitoring.

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis (MS-ON)

18-08-2014

The purpose of this study is to demonstrate the superiority of MD1003 over placebo in the visual improvement of patients suffering from chronic visual loss resulting from multiple sclerosis related optic neuritis.

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