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Hepatitis

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Niemann-Pick type C

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Soft Tissue Sarcoma

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Heart Failure

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Type 2 Diabetes

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Obesity CME

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COPD

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Symptomatic Asthma

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Clinical Case Studies

Group B Streptococcus Infection in Pregnancy

Infection: Genitourinary Infection

Sophie Beal, Former Specialist Registrar in Obstetrics and Gynaecology, St James' Hospital, Leeds, UK

Case History
A 30-year-old woman was admitted in her second pregnancy at 28 weeks gestation with confirmed rupture of membranes. She had previously delivered a stillborn baby at 30 weeks; group B Streptococcus (GBS) infection was implicated.

Meningococcal Meningitis

Infection: Community-acquired Bloodstream Infections

Christopher Duncan, Research Fellow, Sir William Dunn School of Pathology, University of Oxford, Oxford, UK

Case History
A 36-year-old woman was admitted with sudden-onset severe occipital headache, photophobia and vomiting. On physical examination she was afebrile, with obvious photophobia and neck stiffness but no skin rashes.

Blog

Would you trust a doctor to decide if you are an appropriate subject for assisted dying? I wouldn't, neither should you, and my colleagues who are not fortunate enough to be retired will be crazy if they allow themselves to be dragged into the process. Proponents of legislative change should man up and face the implications of their proposals, without hiding behind the medical profession.

Medical Videos

An Animation Demonstrating the Role of Natural Killer Cells
An Animation Demonstrating the Role of Natural Killer Cells
An Animation of The Main Roles of the Immune System
An Animation of The Main Roles of the Immune System

Recent Drug Updates

Medical Journal Abstracts on Immunology

Improved Management of Acute Asthma among Pregnant Women Presenting to the Emergency Department

Thu 30 Oct 2014 -  CHEST Journal

Background: A multicenter study in the late 1990s demonstrated suboptimal emergency asthma care for pregnant women in US emergency departments (EDs). After a decade, follow-up data are lacking. ...

Prediction of Airway Inflammation in Patients with Asymptomatic Asthma by Using Lung Sound Analysis

Sat 04 Oct 2014 -  The Journal of Allergy and Clinical Immunology: In Practice

Background: The intensity and frequency of sounds in a lung sound analysis (LSA) may be related to airway constriction; however, whether any factors of an LSA can predict airway eosinophilic ...

Medical Images

Hypersensitivity rash
Hypersensitivity rash
Grocott stain
Grocott stain
untreated progressors; untreated nonprogressors; treated progressors
untreated progressors; untreated nonprogressors; treated progressors
T2 (weighted) transverse MR image from a white male who presented with increasing confusion
T2 (weighted) transverse MR image from a white male who presented with increasing confusion
T1-weighted (top) Grase (bottom) MRIs
T1-weighted (top) Grase (bottom) MRIs
Gentamicin concentration time profile
Gentamicin concentration time profile
Tuberculous granuloma
Tuberculous granuloma
Ziehl-Neelsen stain
 Ziehl-Neelsen stain
Febrile respiratory illness - chest X-ray
Febrile respiratory illness - chest X-ray
HIV-related seborrhoeic dermatitis
HIV-related seborrhoeic dermatitis

Clinical Guidelines

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Jun 2014

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of..

... recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each Clinical Practice Guideline includes information about: the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans, response evaluation and follow-up.

The Management of Women with Red Cell Antibodies during Pregnancy

May 2014

The purpose of this guideline is to provide guidance on the management of pregnant women with red..

... cell antibodies predating the pregnancy or those developing antibodies during pregnancy. The guideline also includes the management of fetal anaemia caused by red cell antibodies, as well as the early management of the neonate at risk of anaemia and/or hyperbilirubinaemia. It does not address the management of the pregnant woman with anti-platelet antibodies or other autoimmune or alloimmune antibodies.

Online CME

Biological treatment for inflammatory arthritis

After completing this module, you should be able to: know what biological treatments are, be able to explain to patients how they work, know what conditions they are used for,...

Myasthenia gravis: a guide to diagnosis and treatment

After completing this module you should be able to: make a clinical diagnosis of myasthenia gravis, select appropriate diagnostic tests to confirm your diagnosis, and understand the principles of therapy...

Clinical Trials

GHSG-AFM13 An Open-label, Multicenter Phase II Trial With AFM13 in Patients With Relapsed or Refractory Hodgkin Lymphoma

17-12-2014

The study is designed:
- to demonstrate efficacy of AFM13 with an optimized treatment schedule
- to decide whether AFM13 warrants further investigation in a phase III clinical trial

Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (FLUGAZA)

10-12-2014

The hypothesis is that the replacement of the standard fludarabine and cytarabine based therapy by azacytidine could result in an improvement of RFS and OS rates in the experimental arm. To fulfill the medical needs in such frail and elderly population, improvements in terms of atileukemic efficacy in the..

... azacytidine experimental arm should be attained without increasing the therapy-related toxicity or decreasing the patients QoL.

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