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Bedwetting Knowledge Centre and CME

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Hepatitis

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Neuropathic Pain

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Cystic Fibrosis

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Insomnia

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Niemann-Pick type C

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Soft Tissue Sarcoma

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Heart Failure

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Type 2 Diabetes

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Obesity CME

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COPD

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Symptomatic Asthma

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Clinical Case Studies

Massive Pulmonary Embolism

Respiratory Medicine & Allergy: Pulmonary Vascular Diseases

Elizabeth Hadley, Consultant Respiratory and General Physician, Barking, Havering and Redbridge Hospitals University NHS Trust, London, UK
Christopher Kosky, Consultant Respiratory Physicians, Guy's and St Thomas' NHS Foundation Trust, London, UK

Case History
A 46-year-old Afro-Caribbean man presented to hospital after he collapsed with brief loss of consciousness. He was short of breath at rest and felt as if he couldn't take a breath in.

Assessment of the Patient with Sepsis

Infection: The Patient with Sepsis

R. Andrew Seaton, MBChB, MD, DTM&H, FRCP (Edinburgh & Glasgow)
Consultant in Infectious Diseases and General Medicine, Honorary Senior Lecturer,
University of Glasgow, Brownlee Centre for Infectious Diseases and Tropical Medicine, Gartnavel General Hospital, Glasgow, UK

Case History
A previously healthy 19-year-old woman presented to her general practitioner with fever, myalgia, sore throat and fatigue.

Blog

Would you trust a doctor to decide if you are an appropriate subject for assisted dying? I wouldn't, neither should you, and my colleagues who are not fortunate enough to be retired will be crazy if they allow themselves to be dragged into the process. Proponents of legislative change should man up and face the implications of their proposals, without hiding behind the medical profession.

Medical Videos

An Animation Demonstrating the Role of Natural Killer Cells
An Animation Demonstrating the Role of Natural Killer Cells
An Animation of The Main Roles of the Immune System
An Animation of The Main Roles of the Immune System

Recent Drug Updates

Medical Journal Abstracts on Immunology

Improved Management of Acute Asthma among Pregnant Women Presenting to the Emergency Department

Thu 30 Oct 2014 -  Improved Management of Acute Asthma among Pregnant Women Presenting to the Emergency Department

Background: A multicenter study in the late 1990s demonstrated suboptimal emergency asthma care for pregnant women in US emergency departments (EDs). After a decade, follow-up data are lacking. ...

Prediction of Airway Inflammation in Patients with Asymptomatic Asthma by Using Lung Sound Analysis

Sat 04 Oct 2014 -  Prediction of Airway Inflammation in Patients with Asymptomatic Asthma by Using Lung Sound Analysis

Background: The intensity and frequency of sounds in a lung sound analysis (LSA) may be related to airway constriction; however, whether any factors of an LSA can predict airway eosinophilic ...

Medical Images

Longitudinal melanonychia
Longitudinal melanonychia
Metavir stage 2 (F2)
Metavir stage 2 (F2)
Bronchogenic cyst
Bronchogenic cyst
Molluscum contagiosum
Molluscum contagiosum
Cerebral asperglioma on T1-weighted cerebral MRI
Cerebral asperglioma on T1-weighted cerebral MRI
Extrapulmonary TB
Extrapulmonary TB
Abdominal X-ray
Abdominal X-ray
Pneumonias
Pneumonias
Sarcoma on hard palate
Sarcoma on hard palate
Pulmonary angiogram
Pulmonary angiogram

Clinical Guidelines

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

Jun 2014

The ESMO Clinical Practice Guidelines (CPG) are intended to provide the user with a set of..

... recommendations for the best standards of cancer care, based on the findings of evidence-based medicine. Each Clinical Practice Guideline includes information about: the incidence of the malignancy, diagnostic criteria, staging of disease and risk assessment, treatment plans, response evaluation and follow-up.

The Management of Women with Red Cell Antibodies during Pregnancy

May 2014

The purpose of this guideline is to provide guidance on the management of pregnant women with red..

... cell antibodies predating the pregnancy or those developing antibodies during pregnancy. The guideline also includes the management of fetal anaemia caused by red cell antibodies, as well as the early management of the neonate at risk of anaemia and/or hyperbilirubinaemia. It does not address the management of the pregnant woman with anti-platelet antibodies or other autoimmune or alloimmune antibodies.

Online CME

Biological treatment for inflammatory arthritis

After completing this module, you should be able to: know what biological treatments are, be able to explain to patients how they work, know what conditions they are used for,...

Myasthenia gravis: a guide to diagnosis and treatment

After completing this module you should be able to: make a clinical diagnosis of myasthenia gravis, select appropriate diagnostic tests to confirm your diagnosis, and understand the principles of therapy...

Clinical Trials

GHSG-AFM13 An Open-label, Multicenter Phase II Trial With AFM13 in Patients With Relapsed or Refractory Hodgkin Lymphoma

17-12-2014

The study is designed:
- to demonstrate efficacy of AFM13 with an optimized treatment schedule
- to decide whether AFM13 warrants further investigation in a phase III clinical trial

Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (FLUGAZA)

10-12-2014

The hypothesis is that the replacement of the standard fludarabine and cytarabine based therapy by azacytidine could result in an improvement of RFS and OS rates in the experimental arm. To fulfill the medical needs in such frail and elderly population, improvements in terms of atileukemic efficacy in the..

... azacytidine experimental arm should be attained without increasing the therapy-related toxicity or decreasing the patients QoL.

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