ESC Guidelines on Myocardial Revascularization

European Society of Cardiology (ESC) (Nov 2011)

Formulation of the best possible revascularization approach, taking into consideration the social and cultural context also, will often require interaction between cardiologists and cardiac surgeons, referring physicians or other specialists as desirable. Patients need help in taking informed decisions about their treatment, and the most valuable advice will likely be provided to them by the Heart Team.

---

European Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

European Society of Cardiology (Nov 2011)

The present document deals with the management of patients with suspected NSTE-ACS.

Guidelines on the diagnosis and management of acute pulmonary embolism

European Society of Cardiology (Jun 2008)

The task force for the diagnosis and management of Acute Pulmoanary Embolism of the European Society of Cardiology (ESC)

ADHD Clinical Practice Guidelines

American Academy of Pediatrics (Nov 2011)

This clinical practice guideline provides recommendations for the assessment and diagnosis of school-aged children with attention-deficit/hyperactivity disorder (ADHD). This guideline, the first of 2 sets of guidelines to provide recommendations on this condition, is intended for use by primary care clinicians working in primary care settings. The second set of guidelines will address the issue of treatment of children with ADHD.

---

Attention deficit hyperactivity disorder: Diagnosis and management of ADHD in children, young people and adults

NICE (Sep 2008)

This guideline makes recommendations for the diagnosis and management of attention deficit hyperactivity disorder (ADHD) in children, young people and adults. The guideline does not cover the management of ADHD in children younger than 3 years. The term ‘children’ refers to those aged 11 years and younger; ‘young people’ refers to those between 12 and 18 years. However, these categories are flexible and clinicians should use their judgement about a child or young person’s developmental, as opposed to their chronological, age.

---

Management of attention deficit and hyperkinetic disorders in children and young people

Scottish Intercollegiate Guidelines Network (Nov 2011)

The overall aim of this national guideline update is to provide a framework for evidence based assessment and management of ADHD/HKD, from which multidisciplinary and multiagency approaches can be developed locally.

Anaphylaxis: assessment to confirm an anaphylactic episode and the decision to refer after emergency treatment for a suspected anaphylactic episode

NICE (Dec 2011)

This guideline offers best practice advice on the care of adults, young people and children following emergency treatment for suspected anaphylaxis.

---

Antibiotic prophylaxis in surgery

Scottish Intercollegiate Guidelines Network (Nov 2011)

The goals of prophylactic administration of antibiotics to surgical patients are to: - reduce the incidence of surgical site infection - use antibiotics in a manner that is supported by evidence of effectiveness - minimise the effect of antibiotics on the patient’s normal bacterial flora - minimise adverse effects - cause minimal change to the patient’s host defences.

Dementia

NICE (May 2007)

This guideline has been developed to advise on supporting people with dementia and their carers in health and social care. The guideline recommendations have been developed by a multidisciplinary team of health and social care professionals, a person with dementia, carers and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to practitioners and service commissioners in providing and planning high-quality care for those with dementia while also emphasising the importance of the experience of care for people with dementia and carers.

---

EFNS guidelines for the diagnosis and management of Alzheimer's disease

European Federation of Neurological Societies (Nov 2011)

The aim of this revised international guideline was to present a peer-reviewed evidence-based statement for the guidance of practice for clinical neurologists, geriatricians, psychiatrists, and other specialist physicians responsible for the care of patients with AD. Mild cognitive impairment and non- Alzheimer dementias are not included in this guideline.

Erythropoetin (alpha and beta) and darbepoetin for the treatment of cancer-treatment induced anaemia

NICE (Nov 2011)

Erythropoietin analogues with iron injections are recommended as a possible treatment for anaemia caused by cancer treatment only in: women receiving platinum-based chemotherapy for cancer of the ovaries who have a blood haemoglobin level of 8 g/100 ml or lower people who have very severe anaemia and cannot receive blood transfusions. Healthcare professionals should not stop prescribing erythropoietin analogues for people who were already taking them when the guidance was issued. These people should be able to carry on taking erythropoietin analogues until they and their healthcare professionals decide that it is the right time to stop treatment.

---

Guidelines for the management of iron deficiency anaemia

British Society of Gastroenterology (Nov 2011)

These guidelines are primarily intended for gastroenterologists and GI surgeons but are applicable for other doctors seeing patients with IDA. The investigation of overt blood loss is not considered in these guidelines.

Unstable angina and NSTEMI

NICE (Mar 2010)

The term ‘acute coronary syndromes’ encompasses a range of conditions from unstable angina to ST-segment-elevation myocardial infarction (STEMI), arising from thrombus formation on an atheromatous plaque. This guideline addresses the early management of unstable angina and non-ST-segmentelevation myocardial infarction (NSTEMI) once a firm diagnosis has been made and before discharge from hospital. If untreated, the prognosis is poor and mortality high, particularly in people who have had myocardial damage. Appropriate triage, risk assessment and timely use of acute pharmacological or invasive interventions are critical for the prevention of future adverse cardiovascular events (myocardial infarction, stroke, repeat revascularisation or death).

Antenatal and postnatal mental health

NICE (Feb 2007)

The advice in the NICE clinical guideline on mental health problems during pregnancy and after giving birth covers:

---

Antenatal care

NICE (Mar 2008)

The advice in the NICE guideline covers : the routine care that all healthy women can expect to receive during their pregnancy.

Antisocial personality disorder: treatment, management and prevention

NICE (Jan 2009)

Antisocial personality disorder is the name given to a condition that affects a person's thoughts, emotions and behaviour. Antisocial means behaving in a way that is disruptive to, and may be harmful to, other people.

Generalised anxiety disorder and panic disorder (with or without agoraphobia) in adults

NICE (Nov 2011)

This clinical guideline (published January 2011) updates and replaces NICE clinical guideline 22 (published December 2004; amended April 2007). It offers evidence-based advice on the care and treatment of adults with generalised anxiety disorder or panic disorder (with or without agoraphobia. New and updated recommendations on the management of generalised anxiety disorder were included in 2011.

British Guideline on the Management of Asthma

British Thoracic Society (Nov 2011)

The 2008 guideline considered literature published up to March 2007. It contains a completely rewritten section on diagnosis for both adults and children; a section on special situations which includes occupational asthma, asthma in pregnancy and the new topic of difficult asthma; updated sections on pharmacological and non-pharmacological management; and amalgamated sections on patient education and compliance, and on organisation of care and audit. The 2009 revisions include updates to pharmacological management, the management of acute asthma and asthma in pregnancy. Update searches were conducted on inhaler devices but there was insufficient new evidence to change the existing recommendations. The annexes have also been amended to reflect current evidence. The 2011 revisions include updates to monitoring asthma and pharmacological management, and a new section on asthma in adolescents. The timescale of the literature search for each section is given in Annex 1. It is hoped that this asthma guideline continues to serve as a basis for high quality management of both acute and chronic asthma and a stimulus for research into areas of management for which there is little evidence. Sections of the guideline will continue to be updated on the BTS and SIGN websites on an annual basis

---

Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma

National Heart Lung and Blood Institute (Aug 2007)

The EPR 3 Guidelines on Asthma was developed by an expert panel commissioned by the National Asthma Education and Prevention Program (NAEPP) Coordinating Committee (CC), coordinated by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health. Using the 1997 EPR 2 guidelines and the 2004 update of EPR 2 as the framework, the expert panel organized the literature review and final guidelines report around four essential components of asthma care, namely: assessment and monitoring, patient education, control of factors contributing to asthma severity, and pharmacologic treatment. Subtopics were developed for each of these four broad categories.

AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update

American heart association (Nov 2011)

Indeed, the growing body of evidence confirms that in patients with atherosclerotic vascular disease, comprehensive risk factor management reduces risk as assessed by a variety of outcomes, including improved survival, reduced recurrent events, the need for revascularization procedures, and improved quality of life. It is important not only that the healthcare provider implement these recommendations in appropriate patients but also that healthcare systems support this implementation to maximize the benefit to the patient.

Atrial fibrillation

NICE (Jun 2006)

The NICE clinical guideline on atrial fibrillation covers:

---

ESC Management of Atrial Fibrillation

European Society of Cardiology (ESC) (Nov 2011)

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in 1–2% of the general population. Over 6 million Europeans suffer from this arrhythmia, and its prevalence is estimated to at least double in the next 50 years as the population ages. It is now 4 years since the last AF guideline was published, and a new version is now needed.

Assessment, diagnosis and clinical interventions for children and young people with autism spectrum disorders

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline focuses on assessment, diagnosis and clinical interventions for ASD. It considers the evidence for joint working and consultation with children and young people, and with parents and carers. It also considers the evidence for how multidisciplinary and multiagency working can best address the needs of individuals with ASD at all levels of provision (primary, secondary and tertiary care).

Guidelines for treatment of autoimmune neuromuscular transmission disorders

European Federation of Neurological Societies (Nov 2011)

Important progress has been made in our understanding of the autoimmune neuromuscular transmission (NMT) disorders; myasthenia gravis (MG), Lambert–Eaton myasthenic syndrome (LEMS) and neuromyotonia (Isaacs syndrome).

Early management of persistent non-specific low back pain

NICE (May 2009)

This guideline is about the care and treatment that people who have persistent non-specific low back pain can expect from the NHS in England and Wales to help them manage their pain.

Management of invasive meningococcal disease in children and young people

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline makes recommendations on best practice in the recognition and management of meningococcal disease in children and young people up to 16 years of age. It addresses the patient journey through pre-hospital care, referral, diagnostic testing, disease management, follow-up care and rehabilitation and considers public health issues.

Benign Prostatic Hyperplasia

European Association of Urology (Mar 2008)

Benign prostatic hyperplasia (BPH) is a condition intimately related to ageing. Although it is not lifethreatening,

Bipolar disorder : The management of bipolar disorder in adults, children and adolescents, in primary and secondary care

NICE (Jul 2006)

The advice in the NICE guideline covers the care of: - adults who, as a result of critical illness, have stayed in critical care and need rehabilitation. It does not specifically look at the care of: - adults who are having treatment for symptoms and pain in the final stages of a terminal illness - adults whose rehabilitation needs are already routinely assessed and delivered as part of their care, for example, patients who have brief stays in critical care units for immediate postoperative care after major elective surgery, and patients with conditions for which published guidelines already exist – such as head injury, heart attack and stroke.

Borderline personality disorder: treatment and management

NICE (Jan 2009)

This guideline covers the care, treatment and support that people with borderline personality disorder should be offered.

Donor breast milk banks

NICE (Feb 2010)

The advice in the NICE guideline covers: How milk banks should recruit, screen and support women who donate breast milk How milk banks should handle and process the breast milk they receive from donors.

Bronchiolitis in children

Scottish Intercollegiate Guidelines Network (Nov 2011)

There is widespread variation in the management of infants with bronchiolitis both in hospital and, anecdotally, in the community.The guideline aims to reduce the use of unnecessary therapies and investigations, particularly in the acute illness, and to guide referral patterns from primary to secondary and for some, tertiary care.

Caesarean section

NICE (Apr 2004)

The NICE caesarean section clinical guideline covers: - the information women can expect to receive from their doctor or midwife about caesarean section - the most common reasons why they might need to have a caesarean section - the benefits and risks of having a baby by a caesarean section compared with a vaginal birth - what can be done to reduce the chances that women will need a caesarean section - routine tests and treatments you should be offered women who have a caesarean section - the care they can expect to receive before, during and after a caesarean section

Advanced breast cancer: diagnosis and treatment

NICE (Feb 2009)

The advice in the NICE guideline describes the tests, treatment, care and support that patients with advanced breast cancer should be offered. It does not specifically describe the care of patients with early breast cancer or those with rare or non-cancerous tumours of the breast.

---

Advanced breast cancer: diagnosis and treatment

NICE (Feb 2009)

The advice in the NICE guideline describes the tests, treatment, care and support that patients with advanced breast cancer should be offered. It does not specifically describe the care of patients with early breast cancer or those with rare or non-cancerous tumours of the breast.

---

BRCA in breast cancer: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines for BRCA1 and BRCA2 screening in breast cancer

---

Breast cancer (early & locally advanced): diagnosis and treatment

NICE (Feb 2009)

This guideline offers best practice advice on the care of patients with early or locally advanced breast cancer.

---

Breast cancer (early & locally advanced): diagnosis and treatment

NICE (Feb 2009)

This guideline offers best practice advice on the care of patients with early or locally advanced breast cancer.

---

Clinical practice guidelines: Management of Early Breast Cancer

National Health and Medical Research Council (Aug 2001)

These guidelines refer to breast cancer in the early stages

---

Familial breast cancer

NICE (Oct 2006)

The NICE clinical guideline on familial breast cancer covers the care of adult women who may be at increased risk of developing breast cancer because of a family history of breast or other cancers.

---

Guidelines for diagnosis, treatment and follow-up

NHS (Jan 2005)

The first guidelines for breast screening assessment were published in 2001. In the three years since then there have been a number of changes in practice that warrant inclusion in updated guidelines. Most units have now moved from fine needle aspiration (FNA) for cytology to automated core biopsy as the method of first choice for non-operative diagnosis. The guidelines also include recommendations on the indications and use of vacuum assisted mammotomy (VAM), reflecting the increasing use of this method of biopsy in many screening assessment units.

---

Locally recurrent or metastatic breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of locally recurrent or metastatic breast cancer

---

Practical clinical guidelines for assessing and managing menopausal symptoms after breast cancer

Oxford Journals (Jun 2008)

Breast cancer is the most common cause of cancer and the second most common cause of cancer mortality in women, affecting up to one in eight women who survive up to the age of 85 years in developed countries (www.cancer.org).

---

Practical clinical guidelines for assessing and managing menopausal symptoms after breast cancer

Oxford Journals (Jun 2008)

Breast cancer is the most common cause of cancer and the second most common cause of cancer mortality in women, affecting up to one in eight women who survive up to the age of 85 years in developed countries (www.cancer.org).

---

Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of primary breast cancer

Brain metastases

European Federation of Neurological Societies (Nov 2011)

The primary objective has been to establish evidence - based guidelines in regard to the management of patients with brain metastases. The secondary objective has been to identify areas where there are still controversies and clinical trials are needed.

---

High-grade malignant glioma: ESMO Clinical Practice

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of high-grade malignant glioma

Advanced colorectal cancer: ESMO Clinical Practice Guidelines for treatment

ESMO (Dec 2011)

Clinical Practice Guidelines for treatment of advanced colorectal cancer

---

Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of anal cancer

---

Biliary cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of biliary cancer

---

Esophageal cancer: Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of esophageal cancer

---

Familial colorectal cancer risk: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines of familial risk in colorectal cancer

---

Gastric cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of gastric cancer

---

Gastrointestinal stromal tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of gastrointestinal stromal tumours (GIST)

---

Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups

British Society of Gastroenterology (Nov 2011)

The aim, as before, is to provide guidance on the appropriateness, method and frequency of screening for people at moderate and high risk from colorectal cancer. This guidance provides some new recommendations for those with inflammatory bowel disease and for those at moderate risk resulting from a family history of colorectal cancer. In other areas guidance is relatively unchanged, but the recent literature was reviewed and is included where appropriate.

---

Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)

JMG: Journal of Medical Genetics (Feb 2007)

In April 2006, a workshop was organised by a group of European experts in hereditary gastrointestinal cancer (the Mallorca-group), aiming to establish guidelines for the clinical management of Lynch syndrome. 21 experts from nine European countries participated in this workshop. Prior to the meeting, various participants prepared the key management issues of debate according to the latest publications. A systematic literature search using Pubmed and the Cochrane Database of Systematic Reviews reference lists of retrieved articles and manual searches of relevant articles was performed. During the workshop, all recommendations were discussed in detail. Because most of the studies that form the basis for the recommendations were descriptive and/or retrospective in nature, many of them were based on expert opinion. The guidelines described in this manuscript may be helpful for the appropriate management of families with Lynch syndrome. Prospective controlled studies should be undertaken to improve further the care of these families.

---

Guidelines for the management of oesophageal and gastric cancer

British Society of Gastroenterology (Nov 2011)

The original guidelines described the management of oesophageal and gastric cancer within existing practice. This paper updates the guidance to include new evidence and to embed it within the framework of the current UK National Health Service (NHS) Cancer Plan. The revised guidelines are informed by reviews of the literature and collation of evidence by expert contributors. The key recommendations are listed. The sections of the guidelines are broadly the same layout as the earlier version, with some evidence provided in detail to describe areas of development and to support the changes to the recommendations.

---

Guidelines for the management of oesophageal and gastric cancer

British Society of Gastroenterology (Nov 2011)

The original guidelines described the management of oesophageal and gastric cancer within existing practice. This paper updates the guidance to include new evidence and to embed it within the framework of the current UK National Health Service (NHS) Cancer Plan. The revised guidelines are informed by reviews of the literature and collation of evidence by expert contributors. The key recommendations are listed. The sections of the guidelines are broadly the same layout as the earlier version, with some evidence provided in detail to describe areas of development and to support the changes to the recommendations.

---

Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of hepatocellular carcinoma

---

Pancreatic cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of pancreatic cancer

---

Primary colon cancer: ESMO Clinical Practice Guidelines for diagnosis, adjuvant treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of primary colon cancer

---

Rectal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of rectal cancer

Cervical cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of cervical cancer

---

Clinical practice guidelines for the management of women with epithelial ovarian cancer

National Health and Medical Research Council (Mar 2004)

The Clinical practice guidelines for the management of women with epithelial ovarian cancer, aim to: • improve the quality of healthcare for women; • educate those involved in the care of women with epithelial ovarian cancer; • assist the decision-making process by women with epithelial ovarian cancer and their doctors; and • facilitate the optimal treatment of women with epithelial ovarian cancer.

---

Clinical practice guidelines for the management of women with epithelial ovarian cancer

National Health and Medical Research Council (Mar 2004)

The Clinical practice guidelines for the management of women with epithelial ovarian cancer, aim to: • improve the quality of healthcare for women; • educate those involved in the care of women with epithelial ovarian cancer; • assist the decision-making process by women with epithelial ovarian cancer and their doctors; and • facilitate the optimal treatment of women with epithelial ovarian cancer.

---

Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of endometrial cancer

---

Management of cervical cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

The optimal management of cervical cancer involves a multidisciplinary team. The challenge for the team is to individualise treatment. As cervical cancer commonly occurs between the ages of 30 and 45, this includes offering women with early disease the option of having fertility conserving surgery, where appropriate. For those with intermediate or advanced disease the aim is to minimise treatment side effects without compromising the outcome.

---

Management of cervical cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

The optimal management of cervical cancer involves a multidisciplinary team. The challenge for the team is to individualise treatment. As cervical cancer commonly occurs between the ages of 30 and 45, this includes offering women with early disease the option of having fertility conserving surgery, where appropriate. For those with intermediate or advanced disease the aim is to minimise treatment side effects without compromising the outcome.

---

Newly diagnosed and relapsed epithelial ovarian carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of newly diagnosed and relapsed epithelial ovarian carcinoma

---

Non-epithelial ovarian cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of non-epithelial ovarian cancer

Diagnosis and management of head and neck cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

The guideline follows the patient’s journey of care from prevention and awareness through treatment to follow up and rehabilitation, making generic recommendations which hold for all head and neck cancers. The treatment sections focus specifically on cancers of the larynx, oral cavity, oropharynx and hypopharynx, as these are the tumour sites with the highest incidences. The guideline does not cover tumours of the nasopharynx, sinuses, salivary glands or thyroid.

---

Diagnosis and management of head and neck cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

The guideline follows the patient’s journey of care from prevention and awareness through treatment to follow up and rehabilitation, making generic recommendations which hold for all head and neck cancers. The treatment sections focus specifically on cancers of the larynx, oral cavity, oropharynx and hypopharynx, as these are the tumour sites with the highest incidences. The guideline does not cover tumours of the nasopharynx, sinuses, salivary glands or thyroid.

---

Nasopharyngeal cancer: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of nasopharyngeal cancer

---

Squamous cell carcinoma of the head and neck: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of squamous cell carcinoma of the head and neck

Acute myeloblastic leukaemias and myelodysplastic syndromes in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of acute myeloblastic leukaemias and myelodysplastic syndromes in adult patients

---

Chronic lymphocytic leukemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of chronic lymphocytic leukemia

---

Chronic myeloid leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of chronic myeloid leukaemia

---

Diffuse large B-cell non-Hodgkin’s lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of diffuse large B-cell non-Hodgkin’s lymphoma

---

Gastric marginal zone lymphoma of MALT type: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of gastric marginal zone lymphoma of MALT type

---

Hodgkin’s lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of Hodgkin’s lymphoma

---

Multiple myeloma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of multiple myeloma

---

Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of newly diagnosed and relapsed follicular lymphoma

---

Primary cutaneous lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of primary cutaneous lymphomas

---

Rituximab for the treatment of follicular lymphoma

NHS (Jun 2009)

Rituximab within its licensed indication (that is, in combination with cyclophosphamide, vincristine and prednisolone) is recommended as an option for the treatment of symptomatic stage III and IV follicular lymphoma in previously untreated patients.

Clinical practice guidelines: For the prevention, diagnosis and management of Lung cancer

National Health and Medical Research Council (Jul 2004)

The Guidelines for the prevention, diagnosis and management of lung cancer

---

Clinical practice guidelines: For the prevention, diagnosis and management of Lung cancer

National Health and Medical Research Council (Jul 2004)

The Guidelines for the prevention, diagnosis and management of lung cancer

---

Early stage and locally advanced (non-metastatic) non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of early stage and locally advanced (non-metastatic) non-small-cell lung cancer

---

Lung cancer

NICE (Nov 2011)

This clinical guideline (published April 2011) updates and replaces NICE clinical guideline 24 (published February 2005). It offers evidence-based advice on the care and treatment of people with lung cancer. New and updated recommendations are included on communication, diagnosis and staging, selection of patients with non-small-cell lung cancer (NSCLC) for treatment with curative intent, surgery with curative intent for NSCLC, smoking cessation, combination treatment for NSCLC, treatment for small-cell lung cancer (SCLC), managing endobronchial obstruction, managing brain metastases, and follow-up and patient perspectives.

---

Lung cancer

NICE (Nov 2011)

This clinical guideline (published April 2011) updates and replaces NICE clinical guideline 24 (published February 2005). It offers evidence-based advice on the care and treatment of people with lung cancer. New and updated recommendations are included on communication, diagnosis and staging, selection of patients with non-small-cell lung cancer (NSCLC) for treatment with curative intent, surgery with curative intent for NSCLC, smoking cessation, combination treatment for NSCLC, treatment for small-cell lung cancer (SCLC), managing endobronchial obstruction, managing brain metastases, and follow-up and patient perspectives.

---

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of malignant pleural mesothelioma

---

Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and followup

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of metastatic non-small-cell lung cancer

---

Small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of small-cell lung cancer

Cancers of unknown primary site: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of cancers of unknown primary site

---

Neuroendocrine bronchial and thymic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of neuroendocrine bronchial and thymic tumours

---

Neuroendocrine gastroenteropancreatic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of neuroendocrine gastroenteropancreatic tumours

---

Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of thyroid cancer

Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of bone sarcomas

---

Melanoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of melanoma

---

Soft tissue sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of soft tissue sarcomas

---

Trabectedin for the treatment of advanced soft tissue sarcoma

NICE (Feb 2010)

Trabectedin is recommended as a possible treatment for people with advanced soft tissue sarcoma if: treatment with anthracyclines and ifosfamide has failed, or they cannot tolerate anthracyclines and ifosfamide, or anthracyclines and ifosfamide are unsuitable. The manufacturer of trabectedin has agreed to a 'patient access scheme', which means that when a person needs more than five trabectedin treatments, it provides the sixth and any further trabectedin treatments to the NHS free of charge.

---

Trabectedin for the treatment of advanced soft tissue sarcoma

NICE (Feb 2010)

Trabectedin is recommended as a possible treatment for people with advanced soft tissue sarcoma if: treatment with anthracyclines and ifosfamide has failed, or they cannot tolerate anthracyclines and ifosfamide, or anthracyclines and ifosfamide are unsuitable. The manufacturer of trabectedin has agreed to a 'patient access scheme', which means that when a person needs more than five trabectedin treatments, it provides the sixth and any further trabectedin treatments to the NHS free of charge.

Breast cancer screening assessment

NHS (Jan 2005)

The first guidelines for breast screening assessment were published in 2001. In the three years since then there have been a number of changes in practice that warrant inclusion in updated guidelines. Most units have now moved from fine needle aspiration (FNA) for cytology to automated core biopsy as the method of first choice for non-operative diagnosis. The guidelines also include recommendations on the indications and use of vacuum assisted mammotomy (VAM), reflecting the increasing use of this method of biopsy in many screening assessment units.

---

Familial breast cancer

NICE (Oct 2006)

The NICE clinical guideline on familial breast cancer covers the care of adult women who may be at increased risk of developing breast cancer because of a family history of breast or other cancers.

---

Referral for suspected cancer

NICE (Jun 2005)

This guideline is an update of the guideline entitled ‘Referral guidelines for suspected cancer’ published by the Department of Health in 2000. The new guideline takes account of new research evidence and the findings of audits undertaken since the publication of the previous guideline. The recommendations made here supersede those in the earlier guideline.

Improving Outcomes for People with Skin Tumours including Melanoma

NICE (Dec 2011)

This guidance provides recommendations for service provision that are based on the best available evidence, or consensus positions, and supports current national initiatives about skin cancers

---

Improving Outcomes for People with Skin Tumours including Melanoma (update)

NICE (Dec 2011)

This updated guidance contains details about the management of Low-risk Basal Cell Carcinomas

Cancer, fertility and pregnancy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of fertility and pregnancy with cancer

---

Cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines for cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease

---

Control of pain in adults with cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the management of pain in adult patients who have cancer. The guideline includes advice mainly concerning pain secondary to the cancer, but many of the principles outlined are applicable to coexisting painful conditions and pain secondary to treatment of the cancer. It excludes the treatment of pain in children under the age of 12.

---

Control of pain in adults with cancer

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the management of pain in adult patients who have cancer. The guideline includes advice mainly concerning pain secondary to the cancer, but many of the principles outlined are applicable to coexisting painful conditions and pain secondary to treatment of the cancer. It excludes the treatment of pain in children under the age of 12.

---

Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients: ESMO Clinical Practice Guidelines for use

ESMO (Dec 2011)

Clinical Practice Guidelines for using erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients

---

Guideline update for MASCC and ESMO in the prevention of chemotherapy- and radiotherapy-induced nausea and vomiting: results of the Perugia consensus conference

ESMO (Dec 2011)

The European Society of Medical Oncology (ESMO) and the Multinational Association of Supportive Care in Cancer (MASCC) update the guideline thanks to committees dealing with major topics in this field of acute or delayed nausea and vomiting induced by chemotherapy.

---

Hematopoietic growth factors: ESMO Clinical Practice Guidelines for the applications

ESMO (Dec 2011)

Clinical Practice Guidelines for the applications of hematopoietic growth factors

---

Management of cancer pain: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines for the management of cancer pain

---

Management of febrile neutropenia: ESMO Clinical Practice Guidelines for the management of febrile neutropenia

ESMO (Dec 2011)

Clinical Practice Guidelines

---

Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines for the management of oral and gastrointestinal mucositis

---

Management of venous thromboembolism (VTE) in cancer patients: ESMO Clinical Practice Guidelines

ESMO (Dec 2011)

Clinical Practice Guidelines for the management of venous thromboembolism (VTE) in cancer patient

Bladder Cancer Muscle-invasive and Metastatic

European Association of Urology (Nov 2011)

The European Association of Urology (EAU) Guideline Panel for Muscle-invasive and Metastic Bladder Cancer (MIBC) has prepared these guidelines to help urologists assess the evidence-based management of MIBC and to incorporate guideline recommendations into their clinical practice. The EAU Guidelines Panel consists of an international multidisciplinary group of experts in this field. It is evident that optimal treatment strategies for MIBC require the involvement of a specialist multidisciplinary team and a model of integrated care to avoid fragmentation of patient care.

---

Bladder Cancer Muscle-invasive and Metastatic

European Association of Urology (Nov 2011)

The European Association of Urology (EAU) Guideline Panel for Muscle-invasive and Metastic Bladder Cancer (MIBC) has prepared these guidelines to help urologists assess the evidence-based management of MIBC and to incorporate guideline recommendations into their clinical practice. The EAU Guidelines Panel consists of an international multidisciplinary group of experts in this field. It is evident that optimal treatment strategies for MIBC require the involvement of a specialist multidisciplinary team and a model of integrated care to avoid fragmentation of patient care.

---

Bladder cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of bladder cancer

---

Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups

British Society of Gastroenterology (Nov 2011)

The aim, as before, is to provide guidance on the appropriateness, method and frequency of screening for people at moderate and high risk from colorectal cancer. This guidance provides some new recommendations for those with inflammatory bowel disease and for those at moderate risk resulting from a family history of colorectal cancer. In other areas guidance is relatively unchanged, but the recent literature was reviewed and is included where appropriate.

---

Guidelines on TaT1 (Non-muscle invasive) Bladder Cancer

European Association of Urology (Nov 2011)

the guidelines group on non-muscle-invasive bladder cancer decided to integrate the guidelines of TaT1 tumours and CIS in one issue. This overview represents the updated EAU guidelines for non-muscle-invasive bladder cancer (CIS, Ta, T1).

---

Guidelines on TaT1 (Non-muscle invasive) Bladder Cancer

European Association of Urology (Nov 2011)

the guidelines group on non-muscle-invasive bladder cancer decided to integrate the guidelines of TaT1 tumours and CIS in one issue. This overview represents the updated EAU guidelines for non-muscle-invasive bladder cancer (CIS, Ta, T1).

---

Guidelines on Upper Urinary Tract Urothelial Cell Carcinomas

European Association of Urology (Nov 2011)

To provide evidence-based information for the clinical management of upper urinary tract urothelial cell carcinomas (UUT-UCCs) and to help clinicians incorporate these recommendations into their practice. The current update is based on a structured literature search

---

Guidelines on Upper Urinary Tract Urothelial Cell Carcinomas

European Association of Urology (Nov 2011)

To provide evidence-based information for the clinical management of these rare tumours and to help clinicians incorporate these recommendations into their practice. The current update is based on a structured literature search

---

Management of adult testicular germ cell tumours

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the management of testicular cancer. It excludes the management of germ cell testicular tumours in children, germ cell tumours in women and extragonadal tumours.

---

Management of adult testicular germ cell tumours

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the management of testicular cancer. It excludes the management of germ cell testicular tumours in children, germ cell tumours in women and extragonadal tumours.

---

Prostate cancer

NICE (Feb 2008)

This is the first clinical guideline, rather than cancer service guidance, produced by the National Collaborating Centre for Cancer (NCC-C) and deals with prostate cancer. Its management often presents men and their health professionals with difficult decisions about the most appropriate treatment and we hope that this document will provide helpful and appropriate guidance. There are many areas where the research evidence is inadequate or incomplete and so some recommendations are based on the judgements and consensus of the guideline development group (GDG) using the best available evidence. We hope that the recommendations for further research will be taken up urgently by national research bodies and provide more robust evidence for the future.

---

Prostate Cancer

European Association of Urology (Apr 2010)

The European Association of Urology (EAU) Guidelines Group for Prostate Cancer have prepared this guidelines document to assist medical professionals assess the evidence-based management of prostate cancer. The multidisciplinary panel of experts include urologists, radiation oncologists, a medical oncologist, and a pathologist.

---

Prostate cancer

NICE (Feb 2008)

This is the first clinical guideline, rather than cancer service guidance, produced by the National Collaborating Centre for Cancer (NCC-C) and deals with a very common cancer. Its management often presents men and their health professionals with difficult decisions about the most appropriate treatment and we hope that this document will provide helpful and appropriate guidance. There are many areas where the research evidence is inadequate or incomplete and so some recommendations are based on the judgements and consensus of the guideline development group (GDG) using the best available evidence. We hope that the recommendations for further research will be taken up urgently by national research bodies and provide more robust evidence for the future.

---

Prostate Cancer

European Association of Urology (Apr 2010)

The European Association of Urology (EAU) Guidelines Group for Prostate Cancer have prepared this guidelines document to assist medical professionals assess the evidence-based management of prostate cancer. The multidisciplinary panel of experts include urologists, radiation oncologists, a medical oncologist, and a pathologist.

---

Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of prostate cancer

---

Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of renal cell carcinoma

---

Testicular Cancer

European Association of Urology (Mar 2009)

A multidisciplinary team of urologists, medical oncologists, radiotherapists and a pathologist were involved in producing this text, which is based on a structured review of the literature from January 2008 until December 2010 for both the germ cell tumour and non-germ cell sections. Also, data from meta-analysis studies, Cochrane evidence, and the recommendations of the European Germ Cell Cancer Collaborative Group Meeting in Amsterdam in November 2006 have been included.

---

Testicular Cancer

European Association of Urology (Mar 2009)

A multidisciplinary team of urologists, medical oncologists, radiotherapists and a pathologist were involved in producing this text, which is based on a structured review of the literature from January 2008 until December 2010 for both the germ cell tumour and non-germ cell sections. Also, data from meta-analysis studies, Cochrane evidence, and the recommendations of the European Germ Cell Cancer Collaborative Group Meeting in Amsterdam in November 2006 have been included.

---

Testicular non-seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of testicular seminoma

---

Testicular seminoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

ESMO (Dec 2011)

Clinical Practice Guidelines for diagnosis, treatment and follow-up of testicular non-seminoma

AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients With Coronary and Other Atherosclerotic Vascular Disease: 2011 Update

American heart association (Nov 2011)

Indeed, the growing body of evidence confirms that in patients with atherosclerotic vascular disease, comprehensive risk factor management reduces risk as assessed by a variety of outcomes, including improved survival, reduced recurrent events, the need for revascularization procedures, and improved quality of life. It is important not only that the healthcare provider implement these recommendations in appropriate patients but also that healthcare systems support this implementation to maximize the benefit to the patient.

---

Atrial fibrillation

NICE (Jun 2006)

The NICE clinical guideline on atrial fibrillation covers:

---

Blood Pressure Monitoring

UCL (Nov 2011)

This guideline offers a definition of what is a blood pressure as well as describing its various phases. It also highlights the difficulties as well as methods and types of equipment used in measuring blood pressure in children/young people. The appendix demonstrates tables of blood pressure measurements for boys and girls aged between 1 and 17 years in relation to 90th and 95th percentiles.

---

Chest pain of recent onset: assessment and diagnosis of recent onset chest pain or discomfort of suspected cardiac origin

NICE (Mar 2010)

It offers evidence-based advice on the care and support of adults with chest pain thought to be related to the heart. The guideline covers the tests and treatment that should be offered to people while their condition is being diagnosed.

---

Chronic heart failure

NICE (Nov 2011)

This clinical guideline (published August 2010) updates and replaces NICE clinical guideline 5 (published July 2003). It offers evidence-based advice on the care and treatment of people with chronic heart failure. New and updated recommendations are included on diagnosis, pharmacological treatment, monitoring and rehabilitation.

---

ESC Guidelines for the management of grown-up congenital heart disease

European Society of Cardiology (ESC) (Nov 2011)

The aim of practice guidelines is to be evidence based, but, in a relatively young specialty dealing with a variety of diseases and frequently small patient numbers, there is a lack of robust data. It is therefore difficult to use categories of strength of endorsement as have been used in other guidelines documents. The vast majority of recommendations must unfortunately remain based on expert consensus rather than on solid data (level of evidence C).

---

ESC Guidelines on device therapy in heart failure

European Society of Cardiology (ESC) (Nov 2011)

An update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy.

---

ESC Guidelines on the diagnosis and treatment of peripheral artery diseases

European Society of Cardiology (ESC) (Nov 2011)

Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries

---

ESC Guidelines on the management of cardiovascular diseases during pregnancy

European Society of Cardiology (ESC) (Nov 2011)

Knowledge of the risks associated with CVD during pregnancy and their management are of pivotal importance for advising patients before pregnancy. Therefore, guidelines on disease management in pregnancy are of great relevance. Such guidelines have to give special consideration to the fact that all measures concern not only the mother, but the fetus as well.

---

ESC Management of Atrial Fibrillation

European Society of Cardiology (ESC) (Nov 2011)

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in 1–2% of the general population. Over 6 million Europeans suffer from this arrhythmia, and its prevalence is estimated to at least double in the next 50 years as the population ages. It is now 4 years since the last AF guideline was published, and a new version is now needed.

---

ESC Management of Dyslipidaemias

European Society of Cardiology (ESC) (Nov 2011)

These guidelines deal with the management of dyslipidaemias as an essential and integral part of CVD prevention.

---

European guidelines on the management of acute and chronic heart failure

European Society of Cardiology (May 2008)

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008

---

European guidelines on the prevention of cardiovascular disease

European Society of Cardiology (Sep 2007)

European Journal Of Cardiovascular Prevention and Rehabilitation.

---

Guidelines for management of hypertension: report of the fourth working party of the British Hypertension Society, 2004_BHS IV

British Hypertension Society Guidelines (Feb 2004)

These guidelines update previous reports by working parties of the British Hypertension Society (BHS) in 1989, 1993 and 1999. Updating these guidelines is appropriate because, since 1999, there has been much new evidence in key areas that has allowed us to reinforce and extend previous recommendations.

---

Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack

American Heart association (Nov 2011)

The aim of this new statement is to provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of ischemic stroke or transient ischemic attack.

---

Hypertension in pregnancy. The management of hypertensive disorders during pregnancy

NICE (Nov 2011)

This clinical guideline offers evidence-based advice on the care and treatment of women who have or are at risk of developing hypertension (high blood pressure) in pregnancy. It contains advice on the diagnosis and management of hypertension during pregnancy, birth and the postnatal period. It also includes advice for women with chronic hypertension who wish to conceive and for women who have had a pregnancy complicated by hypertension.

---

Hypertension: management of hypertension in adults in primary care

NICE (Nov 2011)

This clinical guideline (published August 2011) updates and replaces NICE clinical guideline 34 (published June 2006). It offers evidence-based advice on the care and treatment of adults with primary hypertension. New and updated recommendations on diagnosis, antihypertensive drug treatment and treatment monitoring were included in 2011.

---

Lipid modification

NICE (May 2008)

This guideline offers best practice advice on the care of adults at high risk of developing CVD or with established CVD.

---

Management of open angle glaucoma and ocular hypertension

The Royal College of Ophalmologists (Jul 2004)

This guideline covers adults (18 and older) with a diagnosis of chronic open angle glaucoma or ocular hypertension and those with chronic open angle glaucoma or ocular hypertension associated with pseudoexfoliation or pigment dispersion. In addition, the guideline will cover populations who have a higher prevalence of glaucoma and may have worse clinical outcomes including people with a family history of glaucoma, younger people (<50 years) and people who are of black African or black Caribbean descent. Options for pharmacological, surgical, laser and complimentary or alternative treatments are considered in terms of clinical effectiveness and cost effectiveness.

---

The management of hypertensive disorders during pregnancy

NICE (Aug 2010)

This clinical guideline contains recommendations for the diagnosis and management of hypertensive disorders during pregnancy in the antenatal, intrapartum and postnatal periods. It includes recommendations for women with chronic hypertension who wish to conceive and recommendations for advice to women after a pregnancy complicated by hypertension.

---

Unstable angina and NSTEMI

NICE (Mar 2010)

The term ‘acute coronary syndromes’ encompasses a range of conditions from unstable angina to ST-segment-elevation myocardial infarction (STEMI), arising from thrombus formation on an atheromatous plaque. This guideline addresses the early management of unstable angina and non-ST-segmentelevation myocardial infarction (NSTEMI) once a firm diagnosis has been made and before discharge from hospital. If untreated, the prognosis is poor and mortality high, particularly in people who have had myocardial damage. Appropriate triage, risk assessment and timely use of acute pharmacological or invasive interventions are critical for the prevention of future adverse cardiovascular events (myocardial infarction, stroke, repeat revascularisation or death).

Cerebral vasculitis

European Federation of Neurological Societies (Nov 2011)

to improve the recognition, diagnosis, and management of cerebral vasculitis throughout Europe.

Chronic fatigue syndrome / Myalgic encephalomyelitis

NICE (Aug 2007)

The guideline covers care provided by healthcare professionals who have direct contact with and make decisions about the care of people with chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy) (CFS/ME). It covers care provided in primary and secondary care, and in specialist centres/teams.

Guideline on management of chronic inflammatory demyelinating polyradiculoneuropathy

European Federation of Neurological Societies (Nov 2011)

The EFNS/PNS consensus guideline was designed to offer diagnostic criteria to balance more evenly specificity, which needs to be higher in research than clinical practice, and sensitivity which might miss disease if set too high.

Anaemia management in chronic kidney disease

NICE (Nov 2011)

This clinical guideline (published February 2011) updates and replaces NICE clinical guideline 39 (published September 2006). The advice in the NICE clinical guideline covers: - detecting and diagnosing anaemia of chronic kidney disease - managing anaemia of chronic kidney disease, and other health problems or treatments that may affect it.

---

Clinical Practice Guidelines for Chronic Kidney Disease in Adults: Part II. Glomerular Filtration Rate, Proteinuria, and Other Markers

United states Department of Veterans affairs (Nov 2011)

The Kidney Disease Outcome Quality Initiative of the National Kidney Foundation published clinical practice guidelines on chronic kidney disease in February 2002. Of the 15 guidelines, the first six are of greatest relevance to family physicians. Part II of this two-part review covers guidelines 4, 5, and 6.

---

Diagnosis and management of chronic kidney disease

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline covers three main areas. Firstly, the evidence for the association of specific risk factors with CKD is presented to help identify which individuals are more likely to develop CKD. Secondly, guidance is provided on how to diagnose CKD principally using blood and urine tests. Thirdly, the guideline contains recommendations on how to slow the progression of CKD and how to reduce the risk of cardiovascular disease.

---

Early identification and management of chronic kidney disease in adults in primary and secondary care

NICE (Sep 2008)

This guideline offers best practice advice on the care of adults with chronic kidney disease.

Chronic obstructive pulmonary disease

NICE (Nov 2011)

This guidance is for the care and treatment of people with chronic obstructive pulmonary disease (which is usually shortened to COPD) in the NHS in England and Wales. It explains guidance (advice) from NICE (the National Institute for Health and Clinical Excellence). It is written for people with COPD but it may also be useful for their families or carers or for anyone with an interest in the condition.

Guidelines on Chronic Pelvis Pain

European Association of Urology (Mar 2008)

The European Association of Urology (EAU) Guidelines Group for Chronic Pelvic Pain have prepared this guidelines document to help medical professionals assess the evidence-based management of chronic pelvic pain. The multidisciplinary panel of experts includes urologists, a neuro-urologist, anaesthesiologists, a gynaecologist and a psychologist.

Management of chronic venous leg ulcers

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides evidence based recommendations on the management of venous leg ulcers and examines assessment, treatment and the prevention of recurrence. Evidence on provision of care is also presented. The guideline does not cover detailed management of patients with chronic leg ulcer in the specialist fields of diabetes, vascular surgery or rheumatoid disease, although indications for referral are considered.

Recognition and assessment of coeliac disease

NICE (May 2009)

This guideline offers best practice advice on the recognition and assessment of coeliac disease and the care of children and adults who are undergoing the diagnostic process for coeliac disease.

Guidelines on the Management of Common Bile Duct Stones (CBDS)

British Society of Gastroenterology (Nov 2011)

Clinicians are now faced with a number of potentially valid options for managing patients with suspected CBDS. It is with this in mind that the following guidelines have been written.

ESC Guidelines for the management of grown-up congenital heart disease

European Society of Cardiology (ESC) (Nov 2011)

The aim of practice guidelines is to be evidence based, but, in a relatively young specialty dealing with a variety of diseases and frequently small patient numbers, there is a lack of robust data. It is therefore difficult to use categories of strength of endorsement as have been used in other guidelines documents. The vast majority of recommendations must unfortunately remain based on expert consensus rather than on solid data (level of evidence C).

Guidelines for care of contact dermatitis

British Journal of Dermatology (Sep 2001)

These guidelines have been prepared for dermatologists on behalf of the British Association of Dermatologists and reflect the best data available at the time the report was prepared. Caution should be exercised in interpreting the data; the results of future studies may require alteration of the conclusions or recommendations in this report. It may be necessary or even desirable to depart from the guidelines in the interests of specific patients and special circumstances. Just as adherence to guidelines may not constitute defence against a claim of negligence, so deviation from them should not necessarily be deemed negligent.

Rehabilitation after Critical Illness

NICE (Mar 2009)

The advice in the NICE guideline covers the care of adults who, as a result of critical illness, have stayed in critical care and need rehabilitation.

Cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis

NICE (Feb 2010)

Peritoneal metastases commonly result from the regional spread of gastrointestinal, gynaecological and other malignancies. Peritoneal carcinomatosis is an advanced form of cancer associated with short survival and poor quality of life, which may lead to bowel obstruction, ascites and pain. This procedure was developed by Paul Sugarbaker at the Washington Cancer Institute. A laparotomy is performed under general anaesthesia and all gross tumour is removed along with the involved organs, peritoneum and tissue.

Reducing the risk of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients admitted to hospital

NICE (Jan 2010)

This guidance is about the care and treatment of people who are at risk of developing deep vein thrombosis (DVT) while in hospital in the NHS in England and Wales.

Dental recall

NICE (Oct 2004)

The purpose of this guideline is to help clinicians assign recall intervals between oral health reviews that are appropriate to the needs of individual patients. The recommendations apply to patients of all ages (both dentate and edentulous) receiving primary care from NHS dental staff in England and Wales. The guideline takes into account the potential of the patient and the dental team to improve or maintain the patient’s quality of life and to reduce morbidity associated with oral and dental disease.

Alcohol - related seizures

European Federation of Neurological Societies (Nov 2011)

These guidelines summarize the current evidence for the diagnosis and management of alcohol - related seizures.

---

Alcohol-use disorders: physical complications

NICE (Jun 2010)

The care of adults and young people (aged 10 years and older) who have any health problems that are completely or partly caused by alcohol use

---

Drug misuse - methadone and buprenorphine: full guidance

NICE (Nov 2011)

Methadone and buprenorphine (given as a tablet or a liquid) are recommended as treatment options for people who are opioid dependent. A decision about which is the better treatment should be made on an individual basis, in consultation with the person, taking into account the possible benefits and risks of each treatment for that particular person. If both drugs are likely to have the same benefits and risks, methadone should be given as the first choice. Different people will need different doses of methadone or buprenorphine. People should take methadone or buprenorphine daily in the presence of their doctor, nurse or community pharmacist for at least the first 3 months of treatment and until they are able to continue their treatment correctly without supervision. Treatment with methadone or buprenorphine should be given as part of a support programme to help the person manage their opioid dependence.

Depression

NICE (Dec 2004)

This guideline was first published in December 2004 (NICE, 2004a; NCCMH, 2004) (referred to as the ‘previous guideline’). The present guideline (referred to as the ‘update’) updates many areas of the previous guideline. There are also new chapters on the experience of depression for people with depression and their carers (Chapter 4), and on the treatment and management of subthreshold depressive symptoms (including dysthymia symptoms) (Chapter 13), which were not part of the scope of the previous guideline. Recommendations categorised as ‘good practice points’ in the previous guideline were reviewed for their current relevance (including issues around consent and advance directives). Further details of what has been updated and what is left unchanged can be found at the beginning of each evidence chapter. The scope for the update also included updating two National Institute for Health and Clinical Excellence (NICE) technology appraisals (TAs) on the use of electroconvulsive therapy (ECT) (TA59) and on computerised cognitive behaviour therapy.

---

Depression in children and young people

NICE (Sep 2005)

The NICE clinical guideline on depression in children and young people covers: - the care children and young people with depression can expect to get from their doctor, nurse or counsellor - the information they can expect to be given - what they can expect from treatment - the kinds of services that can help young people and children with depression, including your family doctor (general practitioner or GP), health staff at your school, and specialists in clinics or hospitals

---

Depression with a chronic physical health problem

NICE (Oct 2009)

This guideline makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older who also have a chronic physical health problem (such as cancer, heart disease, diabetes, or a musculoskeletal, respiratory or neurological disorder).

---

Non-pharmaceutical management of depression in adults

Scottish Intercollegiate Guidelines Network (Nov 2011)

The focus of the guideline is to examine the evidence for depression treatments which may be used as alternatives to prescribed pharmacological therapies. Interventions were prioritised for inclusion by the guideline development group if they were known to be delivered, or be under consideration for delivery, by NHS services in Scotland or if, based on the experience of group members, they were interventions which patients asked about or sought outside of the health service.

Blood glucose monitoring

Great Ormond Street Hospital for Children (Oct 2008)

When performing blood glucose monitoring, staff should be trained in both the theoretical & practical aspects, including the use of the glucose measuring device & instruction on calibration of quality control.

---

Continuous subcutaneous insulin infusion for the treatment of diabetes mellitus

NICE (Jul 2008)

The review and re-appraisal of the use of continuous subcutaneous insulin infusion for the treatment of diabetes mellitus has resulted in a change in the guidance. Specifically there has been a change to the recommendation on the use of continuous subcutaneous insulin infusion in children younger than 12 years with type 1 diabetes mellitus.

---

Diabetes in pregnancy

NICE (Mar 2008)

This clinical guideline contains recommendations for the management of diabetes and its complications in women who wish to conceive and those who are already pregnant. The guideline builds on existing clinical guidelines for routine care during the antenatal, intrapartum and postnatal periods. It focuses on areas where additional or different care should be offered to women with diabetes and their newborn babies.

---

Management of diabetes

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the management of diabetes. For people with type 1 and type 2 diabetes recommendations for lifestyle interventions are included, as are recommendations for the management of cardiovascular, kidney and foot diseases

---

Type 1 diabetes

NICE (Sep 2004)

The NICE clinical guideline on type 1 diabetes covers the NHS care that should be available to adults with type 1 diabetes. It includes recommendations on how the diagnosis should be made and the options that should be offered at different times.

---

Type 2 Diabetes - Diabetic Retinopathy: Early Management and Screening

NICE (Mar 2002)

The national clinical guideline for Type 2 diabetes is comprised of a series of six inter-related guidelines that deal with different aspects of Type 2 diabetes. Throughout this document the entire series of guidelines is referred to as ‘the national guideline’. The aim of the national guideline is to provide recommendations to assist health care professionals in their management of people with Type 2 diabetes and is aimed at all health care professionals providing care to people with diagnosed Type 2 diabetes in primary and secondary care, irrespective of location. Depending on the type, stage and severity of clinical problem, the guidelines may also be valuable to those who work in the tertiary sector of diabetes care.

---

Type 2 Diabetes - Management of Blood Glucose

National Clinical Guideline (Sep 2002)

The NICE clinical guideline on type 2 diabetes – blood glucose covers the management of blood glucose levels and looks at its role in limiting or preventing complications of the condition.

---

Type 2 Diabetes - Management of Blood Pressure and Blood Lipids

NICE (Oct 2002)

This guideline is one of a series on type 2 diabetes; others in the series cover: • screening for retinopathy and early management of the condition (guidance was issued by the National Institute for Clinical Excellence in February 2002) • the prevention and early management of renal disease (guidance was issued by the National Institute for Clinical Excellence in February 2002) • the management of blood glucose (guidance was issued by the National Institute for Clinical Excellence in September 2002) • foot care ( the original guideline, published by the Royal College of General Practitioners in April 2000, will be updated by the National Institute for Clinical Excellence in 2003/04).

---

Type 2 Diabetes - Newer Agents for Blood Glucose Control in Type 2 Diabetes

NICE (May 2009)

This guideline offers best practice advice on the care of people with type 2 diabetes. It does not address care in or before pregnancy, or care by specialist services for specific advanced organ damage (cardiac, renal, eye, vascular, stroke and other services).

---

Type 2 Diabetes - Renal Disease: Prevention and Early Management

NICE (Mar 2002)

The NICE clinical guideline on type 2 diabetes and renal disease covers the prevention and management of renal (kidney) disease.

---

Type 2 diabetes: The Management of Type 2 Diabetes (update)

NICE (May 2009)

This guideline is concerned only with Type 2 diabetes. The underlying disorder is usually that of a background of insulin insensitivity plus a failure of pancreatic insulin secretion to compensate for this.

Management of acute diarrhoea and vomiting due to gastoenteritis in children under 5

NICE (Apr 2009)

This guideline is intended to apply to children younger than 5 years in England and Wales who present to a healthcare professional for advice in any setting. Importantly, it differs from other guidelines in that it was developed using a set of important principles employed for all NICE clinical guidelines. At the outset there was a process of national consultation to determine the key areas of management that should be addressed and to define the exact ‘scope’ of the guideline. Recommendations were based on the best available evidence whenever possible.

Clinical Guidelines for the Management of Disorders of Sex Development in Childhood

Consortium On The Management of Disorders of Sex Development (Aug 2006)

The purpose of these guidelines is to assist health care professionals in the provision of diagnosis,

Drug Misuse and Dependence: UK Guidelines on Clinical Management

Department of Health (Sep 2007)

This document updates and replaces Drug Misuse and Dependence – Guidelines on Clinical Management (UK health departments 1999) – hereafter referred to as the 1999 Clinical Guidelines. It has the same status across the UK as the 1999 Clinical Guidelines.

---

Drug misuse: opioid detoxification

NICE (Jul 2007)

This guideline has been developed to advise on opioid detoxification for drug misuse. The guideline recommendations have been developed by a multidisciplinary team of healthcare professionals, service users, a carer and guideline methodologists after careful consideration of the best available evidence. It is intended that the guideline will be useful to clinicians and service commissioners in providing and planning high-quality care for people who misuse drugs while also emphasising the importance of the experience of care for people who misuse drugs and their carers (see Appendix 1 for more details on the scope of the guideline).

---

Drug misuse: psychosocial interventions

NICE (Jul 2007)

This guideline makes recommendations for the use of psychosocial interventions in the treatment of people who misuse opioids, stimulants and cannabis in the healthcare and criminal justice systems. The patterns of use vary for these drugs, with cannabis the most likely to be used in the UK. Cocaine is the next most commonly used drug in the UK, followed by other stimulants such as amphetamine. Opioids, although presenting the most significant health problem, are used less commonly. A large proportion of people who misuse drugs are polydrug users and do not limit their use to one particular drug. This guideline will not deal with recreational drug use, although opportunistic brief interventions for people who misuse drugs but who are not in formal drug treatment are included. The guideline also does not specifically address drug misuse in pregnancy.

---

Guidance for the pharmacological management of substance misuse among young people

National treatment agency (Nov 2011)

A prerequisite of pharmacological management is a comprehensive assessment of the young person’s needs and risks to that young person, and the establishment of a care plan. Pharmacological management should be provided in conjunction with psychosocial interventions and support, including risk management tailored to the individual. Aftercare provision needs to be put in place, which includes psychosocial interventions to prevent relapse.

Dyspepsia

NICE (Aug 2004)

This national guideline provides evidence-based recommendations for the primary care management of dyspepsia symptoms and underlying causes in adults.

Surgical management of OME

NICE (Feb 2008)

The guideline has been developed with the aim of providing guidance on the appropriate criteria for referral, assessment and optimum surgical management of children younger than 12 years with a suspected diagnosis of OME’ for use in the NHS in England, Wales and Northern Ireland.

Eating disorders

NICE (Aug 2004)

The NICE eating disorders clinical guideline covers physical and psychological treatments, treatment with medicines, and what kinds of services best help people with eating disorders.

Atopic eczema in children

NICE (Dec 2007)

Clinical guidelines have been defined as ‘systematically developed statements which assist clinicians and patients in making decisions about appropriate treatment for specific conditions’. This clinical guideline concerns the management of atopic eczema in children from birth up to the age of 12 years. It has been developed with the aim of providing guidance on: • diagnosis and assessment of the impact of the condition • management during and between flares • information and education to children and their families/caregivers about the condition.

---

Atopic eczema in children

NICE (Dec 2007)

This clinical guideline concerns the management of atopic eczema in children from birth up to the age of 12 years.

---

Management of atopic eczema in primary care

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline focuses on providing recommendations for the management of atopic eczema in children and adults in primary care, based on current evidence for best practice. It includes advice on the various topical treatments for atopic eczema (including emollients (moisturisers), topical corticosteroids, topical calcineurin inhibitors and dressings), anti-infective treatments (such as antibiotics and antiseptics), antihistamines, complementary therapies and the roles of diet and environmental factors. It excludes treatments that are usually carried out in secondary care, such as phototherapy and systemic immunosuppressant drugs.

ESHRE guideline for the diagnosis and treatment of endometriosis

ESHRE (Jun 2011)

The objective was to develop recommendations for the diagnosis and treatment of endometriosis and its associated

Diagnosis and management of epilepsies in children and young people

Scottish Intercollegiate Guidelines Network (Nov 2011)

This is an evidence based guideline covering the diagnosis and management of the epilepsies of children and young people aged from one month to 19 years of age (remaining in secondary education). The terms “children” or “child” are used throughout the guideline to cover the age band indicated above, except where there are issues specific to young people.

---

EFNS guideline on the management of status epilepticus in adults

European Federation of Neurological Societies (Nov 2011)

Recommendations are based on this literature and on our judgement of the relevance of the references to the subject. Recommendations were reached by informative consensus approach.

---

Epilepsy

NICE (Oct 2004)

symptoms.

---

Epilepsy, drug treatment

Great Ormond Street Hospital for Children (Oct 2008)

Attempt to make both a seizure diagnosis and syndrome diagnosis, recognizing that the former may be uncertain and the latter may have to be the closest fit.

Falls

NICE (Nov 2004)

The NICE clinical guideline on falls covers older people who live in the community, either at home, in a retirement complex, or in a residential or nursing home. In this guideline, an older person is defined as someone who is aged 65 or older.

A model for service provision for pregnant women with complex social factors

NICE (Sep 2010)

The guideline has been developed in collaboration with the Social Care Institute for Excellence. It is for professional groups who are routinely involved in the care of pregnant women, including midwives, GPs and primary care professionals who may encounter pregnant women with complex social factors in the course of their professional duties. It is also for those who are responsible for commissioning and planning healthcare and social services. In addition, the guideline will be of relevance to professionals working in social services and education/childcare settings, for example school nurses, substance misuse service workers, reception centre workers and domestic abuse support workers.

---

ESC Guidelines on the management of cardiovascular diseases during pregnancy

European Society of Cardiology (ESC) (Nov 2011)

Knowledge of the risks associated with CVD during pregnancy and their management are of pivotal importance for advising patients before pregnancy. Therefore, guidelines on disease management in pregnancy are of great relevance. Such guidelines have to give special consideration to the fact that all measures concern not only the mother, but the fetus as well.

---

ESC Guidelines on the management of cardiovascular diseases during pregnancy

European Society of Cardiology (ESC) (Nov 2011)

Knowledge of the risks associated with CVD during pregnancy and their management are of pivotal importance for advising patients before pregnancy. Therefore, guidelines on disease management in pregnancy are of great relevance. Such guidelines have to give special consideration to the fact that all measures concern not only the mother, but the fetus as well.

---

Fertility

NICE (Feb 2004)

The aim of this guideline is to offer best practice advice on the care of people in the reproductive age group who perceive that they have problems in conceiving. Between 1998 and 2000, the Royal College of Obstetricians and Gynaecologists (RCOG) published three guidelines on the management of infertility that covered, respectively, initial investigation and management, management in secondary care and management in tertiary care. This guideline is based on those RCOG guidelines and takes into account a new review of the research evidence; it also covers the diagnostic, medical and surgical management of people throughout all stages of their care in primary-, secondary- and tertiary-care settings.

---

Fertility assessment and treatment for people with fertility problems

Royal College of Obstetricians and Gynaecologists, (Feb 2004)

The aim of this guideline is to offer best practice advice on the care of people in the reproductive age group who perceive that they have problems in conceiving. Between 1998 and 2000, the Royal College of Obstetricians and Gynaecologists (RCOG) published three guidelines on the management of infertility that covered, respectively, initial investigation and management, management in secondary care and management in tertiary care. This guideline is based on those RCOG guidelines and takes into account a new review of the research evidence; it also covers the diagnostic, medical and surgical management of people throughout all stages of their care in primary-, secondary- and tertiary-care settings.

---

Induction of labour

NICE (Jun 2008)

The purpose of this guideline is to review all aspects of the methodology of induction of labour and the appropriateness of different approaches in the various clinical circumstances that may call for such an intervention.

---

Intrapartum care

NICE (Sep 2007)

The advice in the NICE guideline covers healthy women who are giving birth at 37-42 weeks (known as 'term').

---

Obstetrical Providers

CRICO/RMF (Jul 2006)

This guideline has been adapted from the Practice Guidelines for Obstetrical Anesthesia and the Guidelines for Regional Anesthesia in Obstetrics as approved by the American Society of Anesthesiologists.2-4 It applies to obstetric patients receiving major neuraxial anesthesia (spinal, epidural, combined spinal- epidural, caudal), general anesthesia, or monitored anesthesia care (MAC) for labor analgesia or operative procedures.

---

Postnatal care

NICE (Jul 2006)

The NICE clinical guideline on postnatal care covers the core care that every healthy woman and healthy baby should be offered during the first 6-8 weeks after the birth.

Feverish illness in children

NICE (May 2007)

This advice in this guideline covers the care and treatment of children aged under 5 years with fever in the NHS in England and Wales.

The Management of Gastric Polyps

British Society of Gastroenterology (Nov 2011)

This guideline aims to characterise gastric polyps and provide a framework for management. However, recommendations for diagnosis and treatment of these polyps remain controversial, as there is no consensus. Specifically, these guidelines do not cover the management of early gastric cancer.

Antibiotic Prophylaxis in Gastrointestinal Endoscopy

British Society of Gastroenterology (Nov 2011)

The revised BSG guidelines recommending a marked reduction of pre-procedure antibiotic usage are available for download below. The practice of administering antibiotics to prevent endocarditis is no longer recommended. Prophylaxis remains indicated prior to endoscopic gastrostomy/jejunostomy procedures.

---

Guidance for Obtaining a Valid Consent for Elective Endoscopic Procedures

British Society of Gastroenterology (Nov 2011)

This document sets out the standards and procedures that are appropriate for elective endoscopic procedures in adults. It is based upon current guidance from the Department of Health, the General Medical Council and other relevant sources.

---

Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures

British Society of Gastroenterology (Nov 2011)

Acute gastro-intestinal haemorrhage in patients on anticoagulant or antiplatelet agents is a high-risk situation. The immediate risk to the patient from haemorrhage may outweigh the risk of thrombosis as a result of stopping anticoagulant or antiplatelet therapy. Patients need to be assessed on an individual basis, and it is not possible to give unequivocal guidance to cover all situations.

---

Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures - Updated Flowchart

British Society of Gastroenterology (Nov 2011)

Updated flowchart for the document entitled: Guidelines for the management of anticoagulant and antiplatelet therapy in patients undergoing endoscopic procedures

---

Guidelines on small bowel enteroscopy and capsule endoscopy in adults

British Society of Gastroenterology (Nov 2011)

Capsule endoscopy and enteroscopy are now the preferred methods to examine the small bowel in most situations. These guidelines are intended to provide an evidence based document describing endoscopic investigation of small bowel disorders.

---

Management of acute upper and lower gastrointestinal bleeding

Scottish Intercollegiate Guidelines Network (Nov 2011)

The BSG guidelines for acute variceal and non-variceal haemorrhage were written 8 and 6 years ago and have become dated. Acute upper gastrointestinal bleeding is a major emergency and the recent National, UK-wide audit demonstrated significant deficiencies in service provision and care, and it is therefore appropriate to update the evidence base for managing acutely bleeding patients. The Scottish Inter-collegiate Guideline Network (SIGN) have, this year, published their guideline ‘Management of Acute Upper and Lower GI Bleeding’.

---

Practice guidance on the management of acute and chronic gastrointestinal problems arising as a result of treatment for cancer

British Society of Gastroenterology (Nov 2011)

The number of patients with chronic gastrointestinal (GI) symptoms after cancer therapies which have a moderate or severe impact on quality of life is similar to the number diagnosed with inflammatory bowel disease annually. However, in contrast to patients with inflammatory bowel disease, most of these patients are not referred for gastroenterological assessment. Clinicians who do see these patients are often unaware of the benefits of targeted investigation (which differ from those required to exclude recurrent cancer), the range of available treatments and how the pathological processes underlying side effects of cancer treatment differ from those in benign GI disorders. This paper aims to help clinicians become aware of the problem and suggests ways in which the panoply of syndromes can be managed.

Management of genital Chlamydia trachomatis infection

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline covers chlamydial infection of the genital tract and rectum. It excludes other sites of infection, eg ocular.

American Gastroenterological Association Medical Position Statement on the Management of Gastroesophageal Reflux Disease

American Gastroenterological Association (Dec 2011)

Medical Position Statement on the Management of Gastroesophageal Reflux Disease

Glaucoma: diagnosis and management of chronic open angle glaucoma and ocular hypertension

NICE (Apr 2009)

This guideline offers best practice advice on the diagnosis and management of COAG and OHT.

British Society for Rheumatology and British Health Professionals in Rheumatology Guideline for the Management of Gout

Oxford Journals (May 2007)

Gout is a common disease both in primary care and hospital practice.

Early management of patients with a head injury

Scottish Intercollegiate Guidelines Network (Nov 2011)

One aim of the guideline is to determine which patients are at risk of intracranial complications. Another is how to identify which patients are likely to benefit from transfer to neurosurgical care, and who should be followed up after discharge.

---

Head injury

NICE (Nov 2007)

This guideline was first published in June 2003. The present guideline is a partial update of only some areas where new evidence has been published since the publication of the original guideline (see CG4 website http://guidance.nice.org.uk/cg41/niceguidance/word/English).

Cluster headache and other trigemino- autonomic cephalgias

European Federation of Neurological Societies (Nov 2011)

These guidelines aim to give evidence - based recommendations for the treatment of cluster headache attacks, for the prophylaxis of cluster headache, for the treatment of paroxysmal hemicranias, and for the treatment of SUNCT syndrome. A brief clinical description of the headache disorders is included. The defi nition of the headache disorders follows the diagnostic criteria of the International Headache Society (IHS).

---

Diagnosis and management of headache in adults. A national clinical guideline

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on evidence for best practice in the diagnosis and management of headache in adults. The International Classification of Headache Disorders lists over 200 headache types and a comprehensive review of all headaches is beyond the scope of these guidelines.16 This guideline focuses on the more common primary headaches such as migraine and tension-type headache, and addresses some of the rarer primary headaches which have recognisable features with specific treatments. Secondary headache due to medication overuse is addressed, as the overuse of headache medication can compromise the management of primary headache. “Red flags” for secondary headache are highlighted. A guide to the main investigations used in headache is provided.

---

Guidelines for All Healthcare Professionals in the Diagnosis and Management of : Migraine / Tension-Type Headache / Cluster Headache / Medication-Overuse Headache

British Association for the Study of Headache (Nov 2011)

The purpose of these guidelines is to suggest strategies of management for the common headache disorders that have been found by specialists to work well. They are intended for all healthcare professionals who manage headache. Whether in general practice or neurology or headache specialist clinics, or in the community, the approach to management is the same. We recommend that health-care commissioners incorporate these guidelines into any agreement for provision of services.

---

Headache

Great Ormond Street Hospital for Children (Oct 2008)

Headache is a common problem in children. Studies of prevalence of any type of headache have shown that up to 50% of 7-year olds and up to 80% of 15-year olds have experienced at least one headache.

---

Treatment of medication overuse headache – guideline of the EFNS headache panel

European Federation of Neurological Societies (Nov 2011)

This guideline aims to give treatment recommendations for this headache

---

Treatment of miscellaneous idiopathic headache disorders (group 4 of the IHS classification) – Report of an EFNS task force

European Federation of Neurological Societies (Nov 2011)

To give expert recommendations for the different drug and non-drug treatment procedures of these different headache disorders based on a literature search and on consensus of an expert panel.

Chronic heart failure

NICE (Nov 2011)

This clinical guideline (published August 2010) updates and replaces NICE clinical guideline 5 (published July 2003). It offers evidence-based advice on the care and treatment of people with chronic heart failure. New and updated recommendations are included on diagnosis, pharmacological treatment, monitoring and rehabilitation.

---

ESC Guidelines on device therapy in heart failure

European Society of Cardiology (ESC) (Nov 2011)

An update of the 2008 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure and the 2007 ESC guidelines for cardiac and resynchronization therapy.

---

European guidelines on the management of acute and chronic heart failure

European Society of Cardiology (May 2008)

ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008

Adefovir dipivoxil and peginterferon alfa-2a for the treatment of chronic hepatitis B

NICE (Feb 2009)

NICE has made the following recommendations about the use of adefovir dipivoxil and peginterferon alfa-2a to treat chronic hepatitis B. These recommendations do not apply to people who are also infected with hepatitis C or D, or HIV.

---

Entecavir for the treatment of chronic hepatitis B

NICE (Sep 2008)

Entecavir, within its marketing authorisation, is recommended as an option for the treatment of people with chronic HBeAg-positive or HBeAg-negative hepatitis B in whom antiviral treatment is indicated.

---

Telbivudine for the treatment of chronic hepatitis B

NICE (Aug 2008)

This guidance does not apply to people with chronic hepatitis B who also have hepatitis C, hepatitis D or HIV.

Peginterferon alfa and ribavirin for the treatment of chronic hepatitis C

NICE (Sep 2010)

This guidance should be read in conjunction with the following NICE guidance: • NICE technology appraisal guidance 75 (TA75) ‘Interferon alfa (pegylated and non-pegylated) and ribavirin for the treatment of chronic hepatitis C’ (which covers moderate to severe hepatitis C) • NICE technology appraisal guidance 106 (TA106) ‘Peginterferon alfa and ribavirin for the treatment of mild chronic hepatitis C’.

Management of hip fracture in older people

SIGN (Jun 2009)

The aim of this guideline is to ensure that older people with a hip fracture receive optimal management. The guideline covers pre-hospital care, management in the emergency department, pre- and post-operative care, discharge planning and rehabilitation.

British HIV Association and Childrens HIV Association guidelines for the management of HIV infection in pregnant women 2008

British HIV Association (Jul 2008)

The success of antenatal testing for HIV means that more clinicians than ever are involved in the care of women with HIV who are pregnant. Despite very few recent randomized controlled trials regarding the use of antiretroviral therapy (ART) in pregnancy or obstetric interventions, practice is changing.

---

British HIV Association guidelines for the treatment of TB/HIV coinfection 2011

BHIVA (Nov 2011)

These guidelines have been drawn up to help physicians manage adults with HIV/TB co-infection.

---

Guidelines for antiretroviral treatment of HIV-2-positive individuals

British HIV Association (Nov 2011)

HIV-2, which is closely related to SIV from sooty mangabeys, was first identified in 1986 in patients with AIDS in Guinea-Bissau and Cape Verde, West Africa. Like HIV-1, HIV-2 is an immunodeficiency virus that causes AIDS in humans. However, although HIV-1 and HIV-2 are related, there are important structural differences between them which influence pathogenicity, natural history and therapy.

---

Guidelines for HIV-associated malignancies 2008

British HIV Association (Nov 2011)

HIV infection is associated with three AIDS-defining malignancies (Kaposi’s sarcoma, high-grade B-cell non- Hodgkin’s lymphoma and invasive cervical cancer) as well as an increased risk of a number of other malignancies. The clinical care of patients with these tumours requires a multidisciplinary approach drawing on the skills and experience of all healthcare professional groups.

---

Guidelines for immunization of HIV-infected adults 2008

British HIV Association (Nov 2011)

These guidelines provide evidence-graded recommendations on the appropriate use of active and passive immunization in HIV-infected adults. There are several factors that make the formulation of HIV-specific immunization guidelines important at a time when highly active antiretroviral therapy (HAART) is modifying the natural history of HIV infection, vaccination practices are changing and new vaccines are becoming available in clinical care.

---

Guidelines for the management of coinfection with HIV-1 and hepatitis B or C virus

British HIV Association (Nov 2011)

The 2010 guidelines have been updated to incorporate all new relevant information that has become available since the previous versions were published in 2005. The 2005 versions came as separate hepatitis B and C guidelines but for 2010 we have decided to amalgamate them into a single document.

---

Guidelines for the management of HIV infection in pregnant women 2008

British HIV Association (Nov 2011)

The success of antenatal testing for HIV means that more clinicians than ever are involved in the care of women with HIV who are pregnant. Despite very few recent randomized controlled trials regarding the use of antiretroviral therapy (ART) in pregnancy or obstetric interventions, practice is changing. This is informed largely by observational data and theoretical considerations and these guidelines reflect this.

---

Guidelines for the management of the sexual and reproductive health of people living with HIV infection

British HIV Association (Nov 2011)

The guidelines have been developed for use by healthcare staff in various disciplines including, gynaecologists, staff in primary care, fertility experts and all those involved in the care of HIV positive individuals. They will also be of use to a wider audience including commissioners, public health specialists and communities or individuals living with and affected by HIV.

---

Guidelines for the treatment of HIV-1-infected adults with antiretroviral therapy

British HIV Association (Nov 2011)

The 2008 BHIVA Guidelines have been updated to incorporate all the new relevant information (including presentations at the 15th Conference on Retroviruses and Opportunistic Infections 2008) since the last iteration. The guidelines follow the methodology outlined below and all the peer-reviewed publications and important, potentially treatment-changing abstracts from the last 2 years have been reviewed.

---

Guidelines for the treatment of opportunistic infection in HIV-seropositive individuals 2011

British HIV Association (Nov 2011)

These guidelines have been drawn up to help physicians investigate and manage HIV-seropositive patients suspected of, or having an opportunistic infection (OI). They are primarily intended to guide practice in the UK and related health systems.

---

Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection

Aidsinfo (Jul 2008)

These updated Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection were developed by the Department of Health and Human Services (HHS) Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children convened by the National Resource Center at the Francois-Xavier Bagnoud Center (FXBC), University of Medicine and Dentistry of New Jersey (UMDNJ); the Health Resources and Services Administration (HRSA); and the National Institutes of Health (NIH).

Acutely ill patients in hospital

NICE (Jul 2007)

This guideline offers best practice advice on the care of adult patients within the acute hospital setting.

Human growth hormone (somatropin) for the treatment of growth failure in children (review)

NICE (May 2010)

NICE recommends human growth hormone (somatropin) as a possible treatment for some children with growth failure.

Guidelines for management of hypertension: report of the fourth working party of the British Hypertension Society, 2004_BHS IV

British Hypertension Society Guidelines (Feb 2004)

These guidelines update previous reports by working parties of the British Hypertension Society (BHS) in 1989, 1993 and 1999. Updating these guidelines is appropriate because, since 1999, there has been much new evidence in key areas that has allowed us to reinforce and extend previous recommendations.

---

Hypertension in pregnancy. The management of hypertensive disorders during pregnancy

NICE (Nov 2011)

This clinical guideline offers evidence-based advice on the care and treatment of women who have or are at risk of developing hypertension (high blood pressure) in pregnancy. It contains advice on the diagnosis and management of hypertension during pregnancy, birth and the postnatal period. It also includes advice for women with chronic hypertension who wish to conceive and for women who have had a pregnancy complicated by hypertension.

---

Hypertension: management of hypertension in adults in primary care

NICE (Nov 2011)

This clinical guideline (published August 2011) updates and replaces NICE clinical guideline 34 (published June 2006). It offers evidence-based advice on the care and treatment of adults with primary hypertension. New and updated recommendations on diagnosis, antihypertensive drug treatment and treatment monitoring were included in 2011.

---

Management of open angle glaucoma and ocular hypertension

The Royal College of Ophalmologists (Jul 2004)

This guideline covers adults (18 and older) with a diagnosis of chronic open angle glaucoma or ocular hypertension and those with chronic open angle glaucoma or ocular hypertension associated with pseudoexfoliation or pigment dispersion. In addition, the guideline will cover populations who have a higher prevalence of glaucoma and may have worse clinical outcomes including people with a family history of glaucoma, younger people (<50 years) and people who are of black African or black Caribbean descent. Options for pharmacological, surgical, laser and complimentary or alternative treatments are considered in terms of clinical effectiveness and cost effectiveness.

---

The management of hypertensive disorders during pregnancy

NICE (Aug 2010)

This clinical guideline contains recommendations for the diagnosis and management of hypertensive disorders during pregnancy in the antenatal, intrapartum and postnatal periods. It includes recommendations for women with chronic hypertension who wish to conceive and recommendations for advice to women after a pregnancy complicated by hypertension.

Investigation, treatment and monitoring of late-onset hypogonadism in males

Journal of Andrology (Mar 2008)

Demographic data clearly demonstrate that the percent of population in the older age group is increasing. Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world.

Faecal incontinence

NICE (Jun 2007)

The task of producing a guideline on the management of faecal incontinence in adults has presented challenges, the greatest of which has been the almost complete absence of high quality evidence for most assessment and treatment methods. The guideline development group was therefore faced with a choice: recommending nothing in the absence of good evidence, or doing the best that we could on lesser quality evidence and expert opinion. We chose the latter as we felt that the needs of patients demanded that we at least provide a starting point. But we urge the reader to remember that little of what is contained in this guideline is based on incontrovertible evidence.

---

Urinary incontinence

NICE (Oct 2006)

This clinical guideline concerns the management of UI in adult women. It includes: • stress UI • OAB (with or without urge UI) • mixed UI. It has been developed with the aim of providing guidance on: • initial and ongoing assessments and investigations • appropriate use of conservative and surgical treatment options • the competence required by surgeons performing the primary and subsequent operative procedures

---

Urinary Incontinence

European Association of Urology (Mar 2009)

This document presents a synthesis of the findings of the 4th International consultation on Incontinence held in July 2008. references have been included in the text, with a focus on new publications covering the time span 2005 to the present.

Infection control

NICE (Jun 2003)

The NICE clinical guideline on infection control provides a set of measures to avoid infection that should be followed by anyone giving or receiving care at home, at a health centre or clinic, or elsewhere in the community.

---

Surgical site infection

NICE (Oct 2008)

The advice in the NICE guideline covers adults and children who are going to have a cut through the skin for an operation.

ESC Guidelines on the prevention, diagnosis, and treatment of infective endocarditis

European Society of Cardiology (ESC) (Nov 2011)

The main objective of the current Task Force was to provide clear and simple recommendations, assisting health care providers in clinical decision making. These recommendations were obtained by expert consensus after thorough review of the available literature. An evidence-based scoring system was used, based on a classification of the strength of recommendation and the levels of evidence.

---

Prophylaxis against infective endocarditis

NICE (Mar 2008)

The advice in this NICE guideline covers Patients who are at risk of infective endocarditis.

Guidelines for the management of inflammatory bowel disease in adults

British Society of Gastroenterology (Nov 2011)

The management of inflammatory bowel disease represents a key component of clinical practice for members of the British Society of Gastroenterology. There has been considerable progress in management strategies affecting all aspects of clinical care since the publication of previous BSG guidelines in 2004, necessitating the present revision.

Oseltamivir, amantadine and zanamivir for the prophylaxis of influenza

NICE (Sep 2008)

NICE has said that its recommendations about oseltamivir and zanamivir should not reduce efforts to give vaccination (also called the flu jab) to people for whom it is recommended in national guidelines.

Irritable bowel syndrome

NICE (Feb 2008)

The advice in the NICE guideline covers the care of adults with irritable bowel syndrome.

Recognition and treatment of neonatal jaundice

NICE (May 2010)

This guideline provides guidance regarding the recognition, assessment and treatment of neonatal jaundice. The advice is based on evidence where this is available and on consensus-based practice where it is not.

Neurogenic Lower Urinary Tract Dysfuction

European Association of Urology (Mar 2008)

The purpose of these clinical guidelines is to provide useful information for clinical practitioners on the incidence, definitions, diagnosis, therapy, and follow-up observation of the condition of neurogenic lower urinary tract dysfunction (NLUTD). These guidelines reflect the current opinion of the experts in this specific pathology and thus represent a state-of-the-art reference for all clinicians, as of the date of its presentation to the European Association of Urology (EAU).

---

The management of lower urinary tract symptoms in men

NICE (May 2010)

This guideline offers best practice advice on the care of men with lower urinary tract symptoms.

Fatty acid mitochondrial disorders

European Federation of Neurological Societies (Nov 2011)

These guidelines reflect consensus in the opinions of experts in the fi eld (Good Practice Points). The consensus was reached by analysing series of treated patients and discussing pre - existing guidelines.

Guidelines for the Treatment of Malaria

WHO (Jan 2006)

Malaria case management remains a vital component of the malaria control strategies. This entails early diagnosis and prompt treatment with effective antimalarial medicines. The WHO Guidelines for the treatment of malaria, which were first published in 2006, provide global, evidence-based recommendations on the case management of malaria, targeted mainly at policy-makers at country level, providing a framework for the development of specific and more detailed national treatment protocols that take into account local antimalarial drug resistance patterns and health service capacity in the country. This second edition of the guidelines revisits the recommendations based on updated evidence. The same presentation format from the first edition has been mainly kept based on feedback from the end-users.

---

UK malaria treatment guidelines

British Infection Society (Dec 2006)

Management of malaria depends on awareness of the diagnosis and on performing the correct diagnostic tests: the diagnosis cannot be excluded until 3 blood specimens have been examined by an experienced microscopist. There are no typical clinical features of malaria, even fever is not invariably present. The optimum diagnostic procedure is examination of thick and thin blood films by an expert to detect and speciate the malarial parasites; P. falciparum malaria can be diagnosed almost as accurately using rapid diagnostic tests (RDTs) which detect plasmodial antigens or enzymes, although RDTs for other Plasmodium species are not as reliable.

Infertility

European Association of Urology (Apr 2010)

The European Association of Urology (EAU) Guideline Panel on Male Infertility has prepared these guidelines aiming to assist urologists and healthcare professionals from related specialities in the treatment of male infertility.

Guidelines on Male Sexual Dysfunction

European Association of Urology (Mar 2009)

Erectile dysfunction (ED, impotence) and premature ejaculation (PE) are the two main complaints in male sexual medicine. New oral therapies have completely changed the diagnostic and therapeutic approach to ED and the Guidelines Office of The European Association of Urology (EAU) has appointed an Expert Panel to update previously published EAU guidelines for ED or impotence. The update is based on a review of available scientific information, current research, and clinical practice in the field. The Expert Panel has also identified critical problems and knowledge gaps, setting priorities for future clinical research.

Medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence

NICE (Jan 2009)

This guideline makes recommendations about how healthcare professionals can help patients to make informed decisions by facilitating the involvement of patients in the decision to prescribe, and how they can support patients to adhere to the prescribed medicine. We have not made separate recommendations for carers and families. The principal relationship is between patient and healthcare professional, and the patient has a right to decide who should be involved in their care. With the patient's consent, carers should have access to appropriate levels of information and support.

The management of bacterial meningitis and meningococcal septicaemia in children and young people younger than 16 years in primary and secondary care

Royal College of Paediatrics and Child Health (Jun 2010)

This guideline offers best practice advice on the care of children and young people younger than 16 years with bacterial meningitis and meningococcal septicaemia.

Alcohol - related seizures

European Federation of Neurological Societies (Nov 2011)

These guidelines summarize the current evidence for the diagnosis and management of alcohol - related seizures.

---

Alcohol-use disorders: physical complications

NICE (Jun 2010)

The care of adults and young people (aged 10 years and older) who have any health problems that are completely or partly caused by alcohol use

---

Antenatal and postnatal mental health

NICE (Feb 2007)

The advice in the NICE clinical guideline on mental health problems during pregnancy and after giving birth covers:

---

Antisocial personality disorder: treatment, management and prevention

NICE (Jan 2009)

Antisocial personality disorder is the name given to a condition that affects a person's thoughts, emotions and behaviour. Antisocial means behaving in a way that is disruptive to, and may be harmful to, other people.

---

Bipolar disorder : The management of bipolar disorder in adults, children and adolescents, in primary and secondary care

NICE (Jul 2006)

The advice in the NICE guideline covers the care of: - adults who, as a result of critical illness, have stayed in critical care and need rehabilitation. It does not specifically look at the care of: - adults who are having treatment for symptoms and pain in the final stages of a terminal illness - adults whose rehabilitation needs are already routinely assessed and delivered as part of their care, for example, patients who have brief stays in critical care units for immediate postoperative care after major elective surgery, and patients with conditions for which published guidelines already exist – such as head injury, heart attack and stroke.

---

Borderline personality disorder: treatment and management

NICE (Jan 2009)

This guideline covers the care, treatment and support that people with borderline personality disorder should be offered.

---

Depression

NICE (Dec 2004)

This guideline was first published in December 2004 (NICE, 2004a; NCCMH, 2004) (referred to as the ‘previous guideline’). The present guideline (referred to as the ‘update’) updates many areas of the previous guideline. There are also new chapters on the experience of depression for people with depression and their carers (Chapter 4), and on the treatment and management of subthreshold depressive symptoms (including dysthymia symptoms) (Chapter 13), which were not part of the scope of the previous guideline. Recommendations categorised as ‘good practice points’ in the previous guideline were reviewed for their current relevance (including issues around consent and advance directives). Further details of what has been updated and what is left unchanged can be found at the beginning of each evidence chapter. The scope for the update also included updating two National Institute for Health and Clinical Excellence (NICE) technology appraisals (TAs) on the use of electroconvulsive therapy (ECT) (TA59) and on computerised cognitive behaviour therapy.

---

Depression in children and young people

NICE (Sep 2005)

The NICE clinical guideline on depression in children and young people covers: - the care children and young people with depression can expect to get from their doctor, nurse or counsellor - the information they can expect to be given - what they can expect from treatment - the kinds of services that can help young people and children with depression, including your family doctor (general practitioner or GP), health staff at your school, and specialists in clinics or hospitals

---

Depression with a chronic physical health problem

NICE (Oct 2009)

This guideline makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older who also have a chronic physical health problem (such as cancer, heart disease, diabetes, or a musculoskeletal, respiratory or neurological disorder).

---

Drug misuse - methadone and buprenorphine: full guidance

NICE (Nov 2011)

Methadone and buprenorphine (given as a tablet or a liquid) are recommended as treatment options for people who are opioid dependent. A decision about which is the better treatment should be made on an individual basis, in consultation with the person, taking into account the possible benefits and risks of each treatment for that particular person. If both drugs are likely to have the same benefits and risks, methadone should be given as the first choice. Different people will need different doses of methadone or buprenorphine. People should take methadone or buprenorphine daily in the presence of their doctor, nurse or community pharmacist for at least the first 3 months of treatment and until they are able to continue their treatment correctly without supervision. Treatment with methadone or buprenorphine should be given as part of a support programme to help the person manage their opioid dependence.

---

Eating disorders

NICE (Aug 2004)

The NICE eating disorders clinical guideline covers physical and psychological treatments, treatment with medicines, and what kinds of services best help people with eating disorders.

---

Non-pharmaceutical management of depression in adults

Scottish Intercollegiate Guidelines Network (Nov 2011)

The focus of the guideline is to examine the evidence for depression treatments which may be used as alternatives to prescribed pharmacological therapies. Interventions were prioritised for inclusion by the guideline development group if they were known to be delivered, or be under consideration for delivery, by NHS services in Scotland or if, based on the experience of group members, they were interventions which patients asked about or sought outside of the health service.

---

Obsessive-compulsive disorder

NICE (Jan 2006)

This guideline has been developed to advise on the identification, treatment and management of obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD).

---

Post-traumatic stress disorder (PTSD)

NICE (Mar 2005)

The NICE clinical guideline on post-traumatic stress disorder (PTSD) covers: - the care people with PTSD can expect to receive from their GP or other healthcare professional - the information they can expect to receive about their condition and its treatment - what treatment they can expect, which may include psychological therapies and drug treatment - the services that may help them with PTSD, including specialist mental health services

---

Self-harm

NICE (Nov 2004)

The NICE clinical guideline on self-harm covers: - the care people who harm themselves can expect to receive from healthcare professionals in hospital and out of hospital - the information they can expect to receive - what they can expect from treatment - what kinds of services best help people who harm themselves

---

Service user experience in adult mental health

NICE (Dec 2011)

This piece of guidance has been developed to advise on improving the experience of care for people using mental health services.

Multiple sclerosis

NICE (Feb 2004)

The guideline has been developed by National Collaborating Centre for Chronic Conditions (NCC-CC) with a commission from the National Institute for Clinical Excellence (NICE). The commission stipulated that the guideline should concentrate on the health (ie NHS) aspects of multiple sclerosis, and that while it would include the interface with other agencies including social services, it would not discuss their detailed provision. An additional stipulation was that topics already covered by an existing NICE appraisal report would be incorporated without further assessment.

---

Use of anti - interferon beta antibody measurements in multiple sclerosis

European Federation of Neurological Societies (Nov 2011)

The objectives of our task force were to: (i) evaluate differences in immunogenicity of IFN β products; (ii) evaluate the reliability and give recommendations on BABs and NABs assays; (iii) evaluate the impact of NABs on clinical effi cacy and give recommendations on the clinical use of measurement of IFN β antibodies; and (iv) review the evidence on prevention of NAB development and the management of patients with NABs.

---

Use of imaging in m ultiple sclerosis

European Federation of Neurological Societies (Nov 2011)

Conventional magnetic resonance imaging (cMRI) has proven to be sensitive for detecting multiple sclerosis (MS) lesions and their changes over time. This exquisite sensitivity has made cMRI the most important paraclinical tool in supporting a diagnosis of MS and establishing a prognosis at the clinical onset of the disease.

Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation

European Society of Cardiology (Nov 2011)

Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation.

---

MI: secondary prevention

NICE (May 2007)

This guideline is very welcome as it clearly emphasises the importance of exercise, smoking habit, diet and cardiac rehabilitation as the pillars that support full recovery. It also clarifies the role of the various treatments available including the best drugs and defines which patients might benefit from interventions such as angioplasty and coronary bypass surgery.

EFNS guidelines on management of narcolepsy.

National Guideline Clearing House (Oct 2006)

EFNS guidelines on management of narcolepsy.

---

Management of narcolepsy in adults

European Federation of Neurological Societies (Nov 2011)

The treatments used for narcolepsy, either pharmacological or behavioural, are diverse. However, the quality of the published pieces of clinical evidence supporting them varies widely, and studies comparing the effi cacy of different substances are lacking.

Cognitive rehabilitation

European Federation of Neurological Societies (Nov 2011)

The aim was to evaluate the existing evidence for the clinical effectiveness of cognitive rehabilitation in stroke and TBI, and provide recommendations for neurological practice. The results were published in 2003 in the European Journal of Neurology and updated in 2005. The present chapter is an update and a revision of these guidelines.

---

Neurological problems in liver transplantation

European Federation of Neurological Societies (Nov 2011)

The recommendation section includes statements classifi ed in levels A – C derived from Classes I – III of evidence according to EFNS guidelines when feasible. For those clinical areas exhibiting Class IV scientifi c evidence, recommendations were based on the agreement obtained and indicated in the text as Good Practice Points (GPP).

---

Use of antibody testing in nervous system disorders

European Federation of Neurological Societies (Nov 2011)

To evaluate service provision and quality assurance schemes for clinically useful autoantibody tests in neurology.

EFNS guidelines on neuropathic pain assessment

European Federation of Neurological Societies (Nov 2011)

We have revised the previous EFNS guidelines on neuropathic pain (NP) assessment, which aimed to provide recommendations for the diagnostic process, screening tools and questionnaires, quantitative sensory testing (QST), microneurography, pain-related reflexes and evoked potentials, functional neuroimaging and skin biopsy.

---

Neuropathic pain - pharmacological management

NICE (Mar 2010)

The full guideline on the pharmacological management of neuropathic pain in adults in non-specialist settings. It contains all the recommendations for healthcare professionals and NHS bodies, details of how they were developed and reviews of the evidence.

Nocturnal enuresis - the management of bedwetting in children and young people

NICE (Oct 2010)

This clinical guideline offers evidence-based advice on the assessment, care and treatment of children and young people up to the age of 19 with bedwetting.

Guidelines on Conservative Treatment of Non-neurogenic Male LUTS

European Association of Urology (Apr 2010)

The new guidelines panel consists of urologists, a pharmacologist, an epidemiologist, and a statistician and has been working on the topic for the last 3 years without financial interests. The new Guidelines are intended to give advice on the pathophysiology and definitions, assessment, treatment, and follow-up of the various forms of non-neurogenic LUTS in men aged 40 years or older. These guidelines cover mainly BPH-LUTS, OAB, and nocturnal polyuria. Lower urinary tract symptoms in children or women and LUTS due to other causes (e.g. neurological diseases, urological tumours of the lower urinary tract, stones disease, or urinary incontinence) are covered by separate EAU guidelines. The new guidelines are primarily written for urologists but can be used by general practitioners as well.

Nutrition Support for Adults Oral Nutrition Support, Enteral Tube Feeding and Parenteral Nutrition

NICE (Feb 2006)

The NICE clinical guideline on nutrition support in adults covers the care of patients with malnutrition or at risk of malnutrition, whether they are in hospital or at home. It doesn't cover malnutrition or its treatments in detail.

---

The provision of a percutaneously placed enteral tube feeding service

British Society of Gastroenterology (Nov 2011)

This guideline, relating to the provision of a percutaneously placed enteral tube feeding service, is focused upon a specific area of nutrition provision that has not been previously targeted.

Management of Obesity

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides evidence based recommendations on the prevention and treatment of obesity within the clinical setting, in children, young people and adults. The focus of prevention is on primary prevention, defined here as intervention when individuals are at a healthy weight and/or overweight to prevent or delay the onset of obesity.

---

Obesity

NICE (Dec 2006)

This is the first national guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children in England and Wales.

Obsessive-compulsive disorder

NICE (Jan 2006)

This guideline has been developed to advise on the identification, treatment and management of obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD).

Osteoarthritis

NICE (Feb 2008)

The advice in the NICE guideline covers the treatment, advice and support that people who have osteoarthritis should be offered by their healthcare professional and when being referred to specialist care.

Osteoporosis in inflammatory bowel disease and coeliac disease

British Society of Gastroenterology (Jun 2007)

Gastroenterologists care for groups of patients at increased risk of osteoporotic fracture, such as those with inflammatory bowel disease (IBD) and coeliac disease. These guidelines review the risks of osteoporosis and fracture in these conditions with a view to identifying subgroups of patients that would benefit from screening and interventions to prevent fractures.

Guidelines on Paediatric Urology

European Association of Urology (Nov 2011)

guidelines. The aim of this close collaboration between a subspecialty group and its parent specialty is to make a document available that may help to increase the quality of care for children with urological problems. The majority of urological clinical problems in children are distinct and in many ways different to those in adults. The aim of this work is to outline a practical and preliminary approach to paediatric urological problems. Complex and rare conditions that require special care with experienced doctors should be referred to designated centres where paediatric urology practice has been fully established and a multidisciplinary approach is available.

Parkinson's disease

NICE (May 2007)

The NICE clinical guideline on Parkinson's disease covers: - the diagnosis of Parkinson's disease and checking the diagnosis regularly - the way people with Parkinson's disease should receive information - the medicines that can be used - other ways of helping with symptoms - how to care for people whose mental health is affected - the care people with Parkinson's disease should receive at the end of their life

Diagnosis and pharmacological management of Parkinson’s disease

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the diagnosis and pharmacological management of PD. It includes comparisons of the accuracy of diagnoses carried out by different healthcare professionals, and the value of different diagnostic tests for differentiating PD from other associated conditions. It includes a comprehensive assessment of pharmacological management of motor and non-motor symptoms associated with PD. It also includes a narrative review of qualitative evidence describing the attitudes, beliefs and opinions of patients with PD across six themes.

---

Early (uncomplicated) Parkinson’s disease

European Federation of Neurological Societies (Nov 2011)

This chapter provides these scientifi cally supported treatment recommendations.

---

Late (complicated) Parkinson’s disease

European Federation of Neurological Societies (Nov 2011)

Patients with advanced Parkinson’s disease (PD) may suffer from any combination of motor and non - motor problems. Doctors and patients must make choices and decide which therapeutic strategies should prevail for each particular instance.

Perioperative hypothermia (inadvertent)

NICE (Apr 2008)

This guidance covers the care and treatment of people who are having an operation in hospital, in the NHS in England and Wales, to reduce their risk of getting cold before, during or after their operation.

ESC Guidelines on the diagnosis and treatment of peripheral artery diseases

European Society of Cardiology (ESC) (Nov 2011)

Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries

Promoting physical activity, active play and sport for pre-school and school-age children and young people in family, pre-school, school and community settings

NICE (Jan 2009)

This guidance is for all those who are involved in promoting physical activity among children and young people, including parents and carers.

Post-polio syndrome

European Federation of Neurological Societies (Nov 2011)

The aim was to revise the existing EFNS task force document, with regard to a common defi nition of PPS, and evaluation of the existing evidence for the effectiveness and safety of therapeutic interventions. By this revision, clinical guidelines for management of PPS are provided.

Post-traumatic stress disorder (PTSD)

NICE (Mar 2005)

The NICE clinical guideline on post-traumatic stress disorder (PTSD) covers: - the care people with PTSD can expect to receive from their GP or other healthcare professional - the information they can expect to receive about their condition and its treatment - what treatment they can expect, which may include psychological therapies and drug treatment - the services that may help them with PTSD, including specialist mental health services

Antenatal and postnatal mental health

NICE (Feb 2007)

The advice in the NICE clinical guideline on mental health problems during pregnancy and after giving birth covers:

Preoperative tests

NICE (Aug 2003)

The NICE clinical guideline on preoperative tests covers tests that are often carried out when someone is due to have a planned (elective) surgical operation and that are carried out before the operation by doctors or nurses in hospitals, preoperative assessment clinics or, in some cases, in the GP’s surgery or health centres. The NICE guideline makes recommendations on the circumstances in which the tests should be done, not done, or considered – for example, whether a certain test is recommended may depend on the patient’s age or how serious the planned operation is.

Pressure relieving devices

NICE (Dec 2003)

The NICE clinical guideline on pressure relieving devices makes recommendations about how the risk of developing a pressure ulcer can be assessed and how pressure ulcers can be prevented by using devices designed to reduce pressure.

Pressure ulcer management

NICE (Sep 2005)

This guideline makes evidence-based recommendations on the management of pressure ulcers in primary and secondary care.

EFNS guidelines on diagnosis and treatment of primary dystonias

European Federation of Neurological Societies (Nov 2011)

To provide a revised version of earlier guidelines published in 2006.

Adalimumab for the treatment of psoriasis

NICE (Jun 2008)

Adalimumab is recommended as a possible treatment for adults with plaque psoriasis only if: their condition is severe and their condition has not improved with other treatments such as ciclosporin, methotrexate and PUVA (psoralen and long-wave ultraviolet radiation), or they have had side effects with these in the past or there is a medical reason why they should not be given these treatments. Adalimumab treatment should be continued beyond 16 weeks only if the psoriasis has clearly improved within this time. The severity of a person's psoriasis before and during treatment should be assessed by considering the redness, thickness and scaliness of the plaques, the area of the body involved, and how the condition affects the person's quality of life. When assessing a person's psoriasis, healthcare professionals should take into account any disabilities or difficulties in communicating, which might mean that standard assessments do not provide accurate information about their condition.

---

Diagnosis and management of psoriasis and psoriatic arthritis in adults

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the diagnosis and management of psoriasis and PsA in adults. It covers early diagnosis of PsA, screening for comorbidities, assessment of disease severity, non-pharmacological treatment, psychological interventions, occupational health, topical treatment, phototherapy, systemic therapy, biologic treatment, referral pathways and the provision of patient information. It excludes psoriasis and PsA in children. Pregnancy and pre-conception care (eg for patients on systemic therapies) are not addressed. Other inflammatory conditions sometimes associated with psoriasis such as palmoplantar pustulosis are not addressed.

Anti-TNF-{alpha} therapy in psoriatic arthritis

Oxford journals (Feb 2005)

These guidelines offer systematic and reviewed recommendations for the prescribing of licensed anti-TNF-α therapies in adult PsA patients with peripheral joint involvement. The guidelines provide a stepwise management plan giving clear inclusion/exclusion and response criteria. The guidelines also set out monitoring requirements.

---

Diagnosis and management of psoriasis and psoriatic arthritis in adults

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the diagnosis and management of psoriasis and PsA in adults. It covers early diagnosis of PsA, screening for comorbidities, assessment of disease severity, non-pharmacological treatment, psychological interventions, occupational health, topical treatment, phototherapy, systemic therapy, biologic treatment, referral pathways and the provision of patient information. It excludes psoriasis and PsA in children. Pregnancy and pre-conception care (eg for patients on systemic therapies) are not addressed. Other inflammatory conditions sometimes associated with psoriasis such as palmoplantar pustulosis are not addressed.

ESC Guidelines for the diagnosis and treatment of pulmonary hypertension

European Society of Cardiology (ESC) (Nov 2011)

The Guidelines on the diagnosis and treatment of pulmonary hypertension (PH) are intended to provide the medical community with updated theoretical and practical information on the management of patients with PH.

Management of sore throat and indications for tonsillectomy

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline covers diagnosis, pain management, antibiotic use, indications for surgical management and postoperative care for acute and recurrent sore throat in children and adults.

Adalimumab, etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis after the failure of a TNF inhibitor

NICE (Nov 2011)

The appraisal of adalimumab and the review of the appraisals of etanercept, infliximab, rituximab and abatacept for the treatment of rheumatoid arthritis have resulted in changes in the guidance. Rituximab in combination with methotrexate is still recommended as an option for the treatment of adults with severe active rheumatoid arthritis who have had an inadequate response to, or have an intolerance of, other DMARDs, including at least one TNF inhibitor. Additional treatment options are now recommended for these adults if rituximab therapy is contraindicated or withdrawn because of an adverse event, specifically: If rituximab is contraindicated or withdrawn, adalimumab, etanercept, infliximab and abatacept, each in combination with methotrexate, are now recommended as treatment options. If rituximab therapy cannot be given because methotrexate is contraindicated or withdrawn because of an adverse event, adalimumab and etanercept, each as monotherapy, are now recommended as treatment options.

---

BSR guidelines on standards of care for persons with rheumatoid arthritis

Oxford Journals (Feb 2005)

This document is intended to help and support the rheumatology team by providing a statement of the minimum standard of care requirements for persons with rheumatoid arthritis. It can also act as the formal record of standards of care as part of the clinical governance process of any rheumatology unit.

---

Certolizumab pegol for the treatment of rheumatoid arthritis

NICE (Feb 2010)

Certolizumab pegol is recommended as a possible treatment for people with rheumatoid arthritis who:

---

Management of early rheumatoid arthritis

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline addresses the diagnosis of early RA, its pharmacological treatment including symptom relief and disease modification, and the role of the multidisciplinary team in improving the care of patients with RA. The guideline does not address the treatment of comorbidities (eg anaemia, osteoporosis), complications of drug therapy and their management, or treatment of extra-articular disease (eg vasculitis, ocular complications, amyloid).

---

Rheumatoid arthritis: the management of rheumatoid arthritis in adults

NICE (Feb 2009)

This guideline offers best practice advice on the care of adults with RA

BSACI guidelines for the management of allergic and non-allergic rhinitis

Clinical and Experimental Allergy, (Dec 2007)

This guidance for the management of patients with allergic and non-allergic rhinitis has been prepared by the Standards of Care Committee (SOCC) of the British Society for Allergy and Clinical Immunology (BSACI). The guideline is based on evidence as well as on expert opinion and is for use by both adult physicians and paediatricians practicing in allergy. The recommendations are evidence graded.

ESC Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery

European Society of Cardiology (ESC) (Nov 2011)

The present guidelines focus on the cardiological management of patients undergoing non-cardiac surgery, i.e. patients where heart disease is a potential source of complications during surgery. The risk of perioperative complications depends on the condition of the patient prior to surgery, the prevalence of co-morbidities, and the magnitude and duration of the surgical procedure.

Core interventions in the treatment and management of schizophrenia in primary and secondary care (update)

NICE (Mar 2009)

The advice in the NICE guideline covers the care, treatment and support that adults (aged 18 and older) with schizophrenia should be offered. This includes people who develop schizophrenia before they are 60 and continue to require treatment after this age.

Self-harm

NICE (Nov 2004)

The NICE clinical guideline on self-harm covers: - the care people who harm themselves can expect to receive from healthcare professionals in hospital and out of hospital - the information they can expect to receive - what they can expect from treatment - what kinds of services best help people who harm themselves

School-based interventions to prevent the uptake of smoking among children

NICE (Feb 2010)

This guidance is for all those responsible for preventing the uptake of smoking by children and young people aged under 19. This includes those working in the NHS, local authorities, education and the wider public, private, voluntary and community sectors. It may also be of interest to children and young people, their parents or carers and other members of the public. For the purposes of this guidance, ‘schools’ includes ‘extended schools’ (where childcare or informal education is provided outside school hours), pupil referral units, secure training and local authority secure units. It also includes further education colleges.

Guidelines for Prevention of Stroke in Patients With Ischemic Stroke or Transient Ischemic Attack

American Heart association (Nov 2011)

The aim of this new statement is to provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of ischemic stroke or transient ischemic attack.

---

Management of patients with stroke or TIA: assessment, investigation, immediate management and secondary prevention

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline replaces SIGN 13 Management of patients with stroke I: Assessment, investigation, immediate management and secondary prevention and SIGN 14 Management of patients with stroke II: Management of carotid stenosis and carotid endarterectomy, which were published in 1997

---

Management of patients with stroke: identification and management of dysphagia

Scottish Intercollegiate Guidelines Network (Nov 2011)

This guideline provides recommendations based on current evidence for best practice in the identification and management of dysphagia after stroke. The guideline does not apply to people with neurological conditions other than stroke, or to people with subarachnoid haemorrhage.

---

Management of patients with stroke: Rehabilitation, prevention and management of complications, and discharge planning

Scottish Intercollegiate Guidelines Network (Nov 2011)

The aim of this national guideline is to assist individual clinicians, primary care teams and hospital departments to optimise their management of stroke patients. The focus is on general management, rehabilitation, the prevention and management of complications and discharge planning, with an emphasis on the first 12 months after stroke.

Therapeutic endoscopic division of epidural adhesions

NICE (Feb 2010)

The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on Therapeutic endoscopic division of epidural adhesions.

Swine flu clinical package

Department of health (Nov 2011)

The swine flu clinical package is a set of tools for use by frontline healthcare professionals, in severe and exceptional circumstances, during a pandemic situation.

ESC Guidelines for the diagnosis and management of syncope

European Society of Cardiology (ESC) (Nov 2011)

Syncope is a T-LOC due to transient global cerebral hypoperfusion characterized by rapid onset, short duration, and spontaneous complete recovery.

EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients

European Federation of Neurological Societies (Nov 2011)

The aim of the present Task Force was to review the strength of evidence to support these interventions and the preparation of recommendations on the therapy of CVST based on the best available evidence for the efficacy and safety of anticoagulant therapy, thrombolysis and symptomatic therapy.

UK Guidelines for the Use of Thyroid Function Tests

British Thyriod Foundation (Jan 2006)

It is hoped that the document will provide guidance for primary care physicians,

Neurological problems in liver transplantation

European Federation of Neurological Societies (Nov 2011)

The recommendation section includes statements classifi ed in levels A – C derived from Classes I – III of evidence according to EFNS guidelines when feasible. For those clinical areas exhibiting Class IV scientifi c evidence, recommendations were based on the agreement obtained and indicated in the text as Good Practice Points (GPP).

---

Organ donation for transplantation: improving donor identification and consent rates for deceased organ donation

NICE (Dec 2011)

This guideline offers best practice advice on improving donor identification and consent rates.

Tuberculosis

NICE (Nov 2011)

The guideline offers evidence-based advice on the diagnosis and treatment of active and latent tuberculosis in adults and children, and on preventing the spread of tuberculosis, for example by offering tests to people at high risk, and by vaccination. The guideline does not explain tuberculosis or its treatments in detail.

Guidelines on Urological Infections

European Association of Urology (Nov 2011)

Due to the increasing threat of resistant pathogens worldwide, it has become imperative to limit the use of antibiotics, and consequently, to monitor established treatment strategies closely. It is the ambition of the present guidelines to provide both the urologist and the physician from other medical specialties with advices in their daily practice. The guidelines cover male and female UTIs, male genital infections, and special fields such as UTIs in paediatric urology, immunosuppression, renal insufficiency and kidney transplant recipients. Much attention is given to antibiotic prophylaxis, with the aim of reducing the misuse of antibiotics in conjunction with surgery. High quality clinical research is strongly encouraged.

---

Urinary tract infection in children

NICE (Aug 2007)

This NICE guideline is about the care and treatment in the NHS in England and Wales of babies, children and young people who are younger than 16 years with a urinary tract infection (UTI).

Guidelines on Urolithiasis

European Association of Urology (Nov 2011)

The European Association of Urology (EAU) Urolithiasis Guideline Panel have prepared these guidelines to help urologists assess the evidence-based management of stones/calculi and to incorporate guideline recommendations into their clinical practice.

Prevention and management of venous thromboembolism

Scottish Intercollegiate Guidelines Network (Nov 2011)

The guideline identifies adult patient groups at risk of VTE and describes the available methods of prophylaxis. Appropriate methods of prophylaxis for specific patient groups are considered in subsequent sections. Important advances in the diagnosis of DVT and PE are described, including the use of diagnostic algorithms incorporating D-dimer assay. Finally, recommendations are made on treatment options for thrombosis in various anatomical regions, including choice of anticoagulant and duration of use, taking account of evidence of risks and benefits of anticoagulant use.

Violence

NICE (Feb 2005)

The NICE clinical guideline on managing disturbed/violent behaviour covers how people in the NHS should try to prevent violent situations from happening, and what they should do if someone becomes violent.

Heavy menstrual bleeding

NICE (Jan 2007)

Heavy menstrual bleeding (HMB) is defined as excessive menstrual blood loss which interferes with a woman's physical, social, emotional and/or material quality of life. It can occur alone or in combination with other symptoms.

---

Long-acting reversible contraception

NICE (Oct 2005)

The NICE clinical guideline on long-acting reversible contraception (LARC) offers the best-practice advice for all women of reproductive age who may wish to regulate their fertility by using LARC methods. It covers specific issues for the use of these methods during the menarche and before the menopause, and by particular groups, including women who have HIV, learning disabilities or physical disabilities, or are younger than 16 years.