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Allergy and Clinical Immunology Drug Data - A-Z (English)
Drug Class Description
Antihistamines.Generic Name
Doxepin hydrochloride 5%Drug Description
Cream.Presentation
Cream, doxepin hydrochloride 5%.Indications
Eczema-associated pruritis.Adult Dosage
Apply thin film three to four times daily; maximum 3 g per application.Child Dosage
Not recommended.Special Precautions
Glaucoma, urinary retention, severe liver disease, mania. Pregnancy, lactation.Interactions
MAOIs, CNS depressants, cimetidine, drugs metabolised by hepatitic microsomal enzymes.Adverse Reactions
Drowsiness; warn patient. Local irritation, dry mouth.Manufacturer
BioglanDrug Availability
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Related News
Study finds benefits of Xolair for Allergic Asthma treatment Allergy and Clinical Immunology Page
New results from the APEX trial of Xolair (omalizumab), from Novartis, show that the drug considerably reduces patients need for steroid use, while at the same time helping disease control and lowering the amount of Asthma exacerbations. Usual treatment for Allergic Astham is oral steroids, but these are associated with weight gain, hypertension, osteoporosis and depression. The data, presented at the 2011 European Respiratory Society congress, shows that in the 12 months after patients started on Xolair (p<0.001), the mean total dose of oral corticosteroids per individual reduced by 34%, with 49% of individuals stopping the oral steroids altogether and 64% considerably reducing their oral corticosteroid dosage. Compared to the previous year, patients experienced a considerable reduction in the amount of asthma exacerbations after 12 months of treatment (53%, 1.7 versus 3.7, 95% CI, p<0.001). Lung function was also found to improve.
