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Allergy and Clinical Immunology Drug Data - A-Z (English)
Drug Class Description
Vitamin A analogues.Generic Name
TretinoinDrug Description
Cream.Presentation
Cream, tretinoin 0.05%. Retinova is not prescribable on the NHS.Indications
Mottled hyperpigmentation, roughness and fine wrinkling of photodamaged skin due to chronic sun exposure.Adult Dosage
Apply lightly to affected areas once daily at night until visible improvement, usually within 3 - 4 months. Maintenance, apply one to three times per week.
Child Dosage
Not recommended.Contra Indications
Personal or familial history of cutaneous epithelioma. Pregnancy.Special Precautions
Eczema, cutaneous irritation. Avoid exposure to sunlight. Avoid eyes, mouth and mucous membranes. Lactation.Interactions
Other topical medications or cosmetics likely to cause skin irritation.Adverse Reactions
Erythema, local irritation, peeling, hyper or hypopigmentation.Manufacturer
Johnson & JohnsonDrug Availability
(POM)Updated
21 May 2009Advert for Healthcare Professionals Only
Related News
Study finds benefits of Xolair for Allergic Asthma treatment Allergy and Clinical Immunology Page
New results from the APEX trial of Xolair (omalizumab), from Novartis, show that the drug considerably reduces patients need for steroid use, while at the same time helping disease control and lowering the amount of Asthma exacerbations. Usual treatment for Allergic Astham is oral steroids, but these are associated with weight gain, hypertension, osteoporosis and depression. The data, presented at the 2011 European Respiratory Society congress, shows that in the 12 months after patients started on Xolair (p<0.001), the mean total dose of oral corticosteroids per individual reduced by 34%, with 49% of individuals stopping the oral steroids altogether and 64% considerably reducing their oral corticosteroid dosage. Compared to the previous year, patients experienced a considerable reduction in the amount of asthma exacerbations after 12 months of treatment (53%, 1.7 versus 3.7, 95% CI, p<0.001). Lung function was also found to improve.
