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Gastroenterology Drug Data - A-Z (English)

Drug Class Description

Antacids.

Generic Name

Aluminium hydroxide dried gel, magnesium hydroxide [co-magaldrox]

Drug Description

Dried aluminium hydroxide gel BP 220 mg, and Magnesium hydroxide BP 195 mg per 5 ml.

Presentation

Suspension

Indications

Antacid therapy in gastric and duodenal ulcer, gastritis, heartburn and gastric hyperacidity.

Adult Dosage

Adults (including the elderly):

10 – 20 ml taken 20 minutes to one hour after meals and at bedtime or as required. Maalox can be taken with water or milk if required

Child Dosage

Not recommended for children under 14 years.

Oral administration.

Contra Indications

Maalox should not be used in patients who are severely debilitated or suffering from renal insufficiency, or if there is severe abdominal pain and/or the possibility of bowel obstruction.

Special Precautions

In patients with renal impairment, plasma levels of both aluminium and magnesium increase. In these patients, a long-term exposure to high doses of aluminium and magnesium salts may lead to dementia, microcytic anemia.

Aluminum hydroxide may be unsafe in patients with porphyria undergoing hemodialysis.

Interactions

Antacids are known to interfere with the absorption of certain drugs including tetracyclines, vitamins, ciprofloxacin, ketoconazole, hydroxychloroquine, chloroquine, chlorpromazine and rifampicin.

Aluminum hydroxide and citrates may result in increased aluminum levels, especially in patients with renal impairment.

Adverse Reactions

Gastrointestinal side effects are uncommon. However, occasional diarrhoea or constipation may occur if use is excessive.

Manufacturer

Aventis

Drug Availability

GSL

Updated

02 June 2009

Drug Languages: en it fr de es no nl pt se

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Maalox Suspension